Novel Benzothiazole Derivatives as Potential Anti-Quorum Sensing Agents for Managing Plant Bacterial Diseases: Synthesis, Antibacterial Activity Assessment, and SAR Study.

Benzothiazoles Bacterial Infections Quorum Sensing Biofilms Anti-Bacterial Agents / pharmacology Plant Diseases Xanthomonas Oryza Microbial Sensitivity Tests
DSF benzothiazole plant bacterial disease quorum sensing virulence factors

Journal

Journal of agricultural and food chemistry
ISSN: 1520-5118
Titre abrégé: J Agric Food Chem
Pays: United States
ID NLM: 0374755

Informations de publication

Date de publication:
03 May 2023
Historique:
medline: 4 5 2023
pubmed: 19 4 2023
entrez: 19 04 2023
Statut: ppublish

Résumé

As quorum sensing (QS) regulates bacterial pathogenicity, antiquorum sensing agents have powerful application potential for controlling bacterial infections and overcoming pesticide/drug resistance. Identifying anti-QS agents thus represents a promising approach in agrochemical development. In this study, the anti-QS potency of 53 newly prepared benzothiazole derivatives containing an isopropanolamine moiety was analyzed, and structure-activity relationships were examined. Compound

Identifiants

DOI: 10.1021/acs.jafc.2c07810 PMID: 37073686
pubmed: 37073686
doi: 10.1021/acs.jafc.2c07810
doi:

Substances chimiques

Benzothiazoles 0
Anti-Bacterial Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

6525-6540

Auteurs

Pan-Long Chu (PL)

National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.

Yu-Mei Feng (YM)

National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.

Zhou-Qing Long (ZQ)

National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.

Wan-Lin Xiao (WL)

National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.

Jin Ji (J)

National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.

Xiang Zhou (X)

National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.

Pu-Ying Qi (PY)

National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.

Tai-Hong Zhang (TH)

National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.

Heng Zhang (H)

National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.

Li-Wei Liu (LW)

National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.

Song Yang (S)

National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang 550025, China.
ORCID: 0000-0003-1301-3030

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Classifications MeSH

questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzothiazoles › Novel Benzothiazole Derivatives as Potential...
questionsmedicales.fr › Infection › Infections bactériennes et mycoses › Infections bactériennes › Novel Benzothiazole Derivatives as Potential...
questionsmedicales.fr › Phénomènes microbiologiques › Interactions microbiennes › Détection du quorum › Novel Benzothiazole Derivatives as Potential...
questionsmedicales.fr › Phénomènes microbiologiques › Biofilms › Novel Benzothiazole Derivatives as Potential...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Novel Benzothiazole Derivatives as Potential...
questionsmedicales.fr › Phénomènes physiologiques des plantes › Maladies des plantes › Novel Benzothiazole Derivatives as Potential...
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Xanthomonadaceae › Xanthomonas › Novel Benzothiazole Derivatives as Potential...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Poaceae › Oryza › Novel Benzothiazole Derivatives as Potential...
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Novel Benzothiazole Derivatives as Potential...