Association between prehospital end-tidal carbon dioxide levels and mortality in patients with suspected severe traumatic brain injury.
Carbon dioxide
Critical care
Endotracheal intubation
Traumatic brain injury
Ventilation
Journal
Intensive care medicine
ISSN: 1432-1238
Titre abrégé: Intensive Care Med
Pays: United States
ID NLM: 7704851
Informations de publication
Date de publication:
05 2023
05 2023
Historique:
received:
26
10
2022
accepted:
19
02
2023
medline:
25
5
2023
pubmed:
19
4
2023
entrez:
19
04
2023
Statut:
ppublish
Résumé
Severe traumatic brain injury is a leading cause of mortality and morbidity, and these patients are frequently intubated in the prehospital setting. Cerebral perfusion and intracranial pressure are influenced by the arterial partial pressure of CO The BRAIN-PROTECT study is an observational multicenter study. Patients with severe traumatic brain injury, treated by Dutch Helicopter Emergency Medical Services between February 2012 and December 2017, were included. Follow-up continued for 1 year after inclusion. End-tidal CO A total of 1776 patients were eligible for analysis. An L-shaped association between end-tidal CO A safe zone of 35-45 mmHg for end-tidal CO
Identifiants
pubmed: 37074395
doi: 10.1007/s00134-023-07012-z
pii: 10.1007/s00134-023-07012-z
pmc: PMC10205841
doi:
Substances chimiques
Carbon Dioxide
142M471B3J
Types de publication
Multicenter Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
491-504Subventions
Organisme : Achmea
ID : Grant Z644
Organisme : Hersenstichting
ID : Grant F2010(1)-14
Investigateurs
Anne de Boer
(A)
Johannes C Goslings
(JC)
Sven H van Helden
(SH)
Danique Hesselink
(D)
Gijs van Aken
(G)
Albertus Beishuizen
(A)
Rolf E Egberink
(RE)
Nancy Ter Bogt
(N)
Mariska A C de Jongh
(MAC)
Koen Lansink
(K)
Koen Lansink
(K)
Gerwin Roks
(G)
Pieter Joosse
(P)
Kees J Ponsen
(KJ)
Lukas L van Spengler
(LL)
Stasja Asper
(S)
Saskia M Peerdeman
(SM)
Robert J Houmes
(RJ)
Jan van Ditshuizen
(J)
Tea van Voorden
(T)
Michael J R Edwards
(MJR)
Bert Dercksen
(B)
Rob Spanjersberg
(R)
Lieneke Venema
(L)
Ellen Weelink
(E)
Inge H F Reininga
(IHF)
Gerard Innemee
(G)
Matthijs de Visser
(M)
Marcel A de Leeuw
(MA)
Fabian O Kooij
(FO)
Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2023. The Author(s).
Références
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