Spontaneous ciliary body detachment in a Marfan patient: A case of personalized management.
Ciliary body detachment
Marfan syndrome
Ocular hypotony
Personalized medicine
Journal
American journal of ophthalmology case reports
ISSN: 2451-9936
Titre abrégé: Am J Ophthalmol Case Rep
Pays: United States
ID NLM: 101679941
Informations de publication
Date de publication:
Jun 2023
Jun 2023
Historique:
received:
10
11
2022
revised:
20
02
2023
accepted:
29
03
2023
medline:
20
4
2023
pubmed:
20
4
2023
entrez:
20
04
2023
Statut:
epublish
Résumé
We present a case of a patient with Marfan Syndrome who underwent a personalized approach to manage a spontaneous ciliary body detachment and degeneration of the ciliary processes, causing refractive ocular hypotony. A 20-year-old MFS man, with a history of bilateral juvenile cataract surgery with failed IOL positioning due to subluxation and consequent explantation, was referred to our clinic after the discovery of persistent ocular hypotonia in his left eye for the past two months, non-responder to corticosteroids. Slit-lamp examination showed shallow anterior chamber and aphakia, with chorioretinal folds, optic disc swelling and mild peripheral retinal lifting. Intraocular pressure (IOP) was 4 mmHg. Ultrasound biomicroscopy (UBM) revealed the presence of a flat, annular ciliochoroidal detachment, posterior pole congestion and total ciliary body separation. One-month systemic therapy with corticosteroids revealed ineffective, and a newly performed UBM showed a significant reduction in the number and thickness of the ciliary processes. At this point, he underwent 23-gauge pars plana vitrectomy with silicone oil endotamponade, combined with a focal A rare case of spontaneous ciliary body detachment in a long standing aphakic MFS patient was successfully managed with focal
Identifiants
pubmed: 37077295
doi: 10.1016/j.ajoc.2023.101840
pii: S2451-9936(23)00048-8
pmc: PMC10106476
doi:
Types de publication
Case Reports
Langues
eng
Pagination
101840Informations de copyright
© 2023 The Authors.
Déclaration de conflit d'intérêts
The authors declare no conflict of interests.
Références
BMJ Case Rep. 2016 May 19;2016:
pubmed: 27199441
Ophthalmology. 1996 May;103(5):827-32
pubmed: 8637695
Am J Ophthalmol. 1998 May;125(5):666-72
pubmed: 9625550
Arch Ophthalmol. 1995 Jan;113(1):103-9
pubmed: 7826283
J Med Genet. 2010 Jul;47(7):476-85
pubmed: 20591885
Surv Ophthalmol. 1995 Jan-Feb;39(4):265-92
pubmed: 7725227
Eur J Ophthalmol. 2012 Sep-Oct;22(5):830-3
pubmed: 22344469
J Med Case Rep. 2017 Jan 23;11(1):22
pubmed: 28110637
Acta Ophthalmol Scand. 2000 Dec;78(6):718-9
pubmed: 11191857
Eur J Ophthalmol. 2005 Mar-Apr;15(2):277-83
pubmed: 15812774
Ann Ocul (Paris). 1970 Dec;203(12):1067-76
pubmed: 5515395
Curr Opin Cardiol. 2005 May;20(3):194-200
pubmed: 15861007
Retina. 1995;15(4):312-8
pubmed: 8545577
Am J Ophthalmol. 2001 Sep;132(3):429-31
pubmed: 11530070
Am J Ophthalmol. 1992 Sep 15;114(3):257-79
pubmed: 1524114
Ophthalmology. 2011 Feb;118(2):260-4
pubmed: 20801513
Ophthalmic Surg Lasers Imaging Retina. 2015 Oct;46(9):936-41
pubmed: 26469233
J Med Case Rep. 2020 Aug 6;14(1):121
pubmed: 32758276
Retina. 2021 Jun 1;41(6):1174-1181
pubmed: 33079790
J Clin Med. 2022 Aug 09;11(16):
pubmed: 36012882