Single probe light reflectance spectroscopy and parameter spectrum feature extraction in experimental skin cancer detection and classification.
cancer
detection and classification
extracted features
reflectance spectroscopy
single optical probe
Journal
Journal of biophotonics
ISSN: 1864-0648
Titre abrégé: J Biophotonics
Pays: Germany
ID NLM: 101318567
Informations de publication
Date de publication:
08 2023
08 2023
Historique:
revised:
16
04
2023
received:
02
01
2023
accepted:
16
04
2023
medline:
7
8
2023
pubmed:
20
4
2023
entrez:
20
04
2023
Statut:
ppublish
Résumé
Skin cancer, an anomalous development of skin cells in the epidermis, is among the most common types of cancer worldwide. Because of its clinical importance and to improve early diagnosis and patient management, there is an urgent need to develop noninvasive, accurate medical diagnostic tools. To this aim, light reflectance spectroscopy over the visible and near-infrared spectral range (400-1000 nm) based on a single-fiber six-around-one optical probe was applied to extract nine features used for diagnostics. These features include skewness, entropy, energy, kurtosis, scattering amplitude, and others, and are spread over each of four different spectral signatures, namely, light reflectance, absorbance, scattering profile approximation, and absorption/scattering ratio. Our preliminary studies focused on 11 adult patients with diagnoses of malignant melanoma (n = 4), basal cell carcinoma (n = 5), and squamous cell carcinoma (n = 2) in a variety of locations on the body. Measurements were taken first in vivo before surgery, at the site of the lesion and from healthy skin of the same patient, and ex vivo after surgical excision, where the lesion was rinsed in saline solution and measurements of the reflected light from the "inside" facing plane of the tissue were taken in the same manner. Overall, experimental results demonstrate that by examining a variety of wavebands, features, and statistical metrics, we can detect and distinguish cancer from normal tissue and different cancer subtypes. Nevertheless, discrepancies in results between in vivo and ex vivo tissue were observed and explanations for these discrepancies are discussed.
Identifiants
pubmed: 37078262
doi: 10.1002/jbio.202300001
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e202300001Informations de copyright
© 2023 Wiley-VCH GmbH.
Références
A. Marusyk, K. Polyak, Biochim. Biophys. Acta 2010, 1805, 105.
S. J. Diaz-Cano, Int. J. Mol. Sci. 2012, 3, 1951.
C. Wittekind, M. Neid, Oncology 2005, 69, 14.
W. G. Jiang, A. J. Sanders, M. Katoh, H. Ungefroren, F. Gieseler, M. Prince, S. K. Thompson, M. Zollo, D. Spano, P. Dhawan, D. Sliva, P. R. Subbarayan, M. Sarkar, K. Honoki, H. Fujii, A. G. Georgakilas, A. Amedei, E. Niccolai, A. Amin, S. S. Ashraf, L. Ye, W. G. Helferich, X. Yang, C. S. Boosani, G. Guha, M. R. Ciriolo, K. Aquilano, S. Chen, A. S. Azmi, W. N. Keith, A. Bilsland, D. Bhakta, D. Halicka, S. Nowsheen, F. Pantano, D. Santini, Semin. Cancer Biol. 2015, 35(Suppl), S244.
W. Zhang, W. Zeng, A. Jiang, Z. He, X. Shen, X. Dong, J. Feng, H. Lu, Cancer. Med. 2021, 10, 4905.
M. Fijałkowska, M. Koziej, B. Antoszewski, Sci. Rep. 2021, 11, 12391.
T. R. Humphreys, Clin. Cornerstone. 2001, 4, 23.
L. L. Griffin, F. R. Ali, J. T. Lear, Clin. Med. 2016, 16, 62.
A. Sandru, S. Voinea, E. Panaitescu, A. Blidaru, J. Med. Life 2014, 7, 572.
W. E. Damsky Jr., L. E. Rosenbaum, M. Bosenberg, Cancers 2011, 3, 126.
K. Li, J. Korean. Med. Assoc. 2018, 61, 649.
O. Yélamos, R. P. Braun, K. Liopyris, Z. J. Wolner, K. Kerl, P. Gerami, A. A. Marghoob, J. Am. Acad. Dermatol. 2019, 80, 365.
M. Karpuz, M. Silindir-Gunay, A. Y. Ozer, Cancer Biother. Radiopharm. 2018, 33, 39.
M. Solomon, Y. Liu, M. Y. Berezin, S. Achilefu, Med. Princ. Pract. 2011, 20, 397.
Y. Zhang, X. Wu, L. He, C. Meng, S. Du, J. Bao, Y. Zheng, Transl. Cancer Res. 2020, 9, 1265.
D. J. Carpenter, M. B. Sajisevi, N. Chapurin, C. S. Brown, T. Cheng, G. M. Palmer, D. S. Stevenson, C. L. Rao, R. P. Hall, C. R. Woodard, Lasers Surg. Med. 2018, 50, 246.
Q. Liu, World. J. Clin. Oncol. 2011, 2, 50.
E. Salomatina, B. Jiang, J. Novak, A. N. Yaroslavsky, J. Biomed. Opt. 2006, 11, 064026.
I. Zeković, T. Dramićanin, L. Lenhardt, J. Bandić, M. D. Dramićanin, Appl. Spectrosc. 2014, 68, 823.
N. Lue, J. W. Kang, C.-C. Yu, I. Barman, N. C. Dingari, M. S. Feld, R. R. Dasari, M. Fitzmaurice, PLoS One 2012, 7, e30887.
K. Sokolov, L. T. Nieman, A. Myakov, A. Gillenwater, Technol. Cancer Res. Treat. 2004, 3, 1.
S. Akter, G. Hossain, I. Nishidate, H. Hazama, K. Awazu, J. Near Infrared Spect. 2018, 26, 337.
J. S. Soares, I. Barman, N. C. Dingari, Z. Volynskaya, W. Liu, N. Klein, D. Plecha, R. R. Dasari, M. Fitzmaurice, Proc. Natl. Acad. Sci. U S A 2013, 110, 471.
A. Keller, P. Bialecki, T. J. Wilhelm, M. K. Vetter, Biomed. Opt. Express. 2018, 9, 1069.
P. Rejmstad, P. Zsigmond, K. Wårdell, Opt. Exp. 2017, 25, 8192.
B. Chen, Y. Zhang, S. Gao, D. Li, Sensors 2021, 21, 3745.
E. J. M. Baltussen, P. Snaebjornsson, S. G. Brouwer de Koning, H. J. C. M. Sterenborg, A. G. J. Aalbers, N. Kok, G. L. Beets, B. H. W. Hendriks, K. F. D. Kuhlmann, T. J. M. Ruers, J. Biomed. Opt. 2017, 22, 1.
S. G. Brouwer de Koning, E. J. M. Baltussen, M. B. Karakullukcu, B. Dashtbozorg, L. A. Smit, R. Dirven, B. H. W. Hendriks, H. J. C. M. Sterenborg, T. J. M. Ruers, J. Biomed. Opt. 2018, 23, 121611.
E. J. A. Romeu, G. Escobedo, A. Campos-Espinosa, I. I. Romero-Bello, J. Moreno-González, D. A. Fabila-Bustos, A. V. Reed, S. S. Isakina, J. M. R. Vázquez, C. Guzmán, J. Biomed. Opt. 2018, 23, 115005.
G. Zonios, I. Bassukas, A. Dimou, Appl. Opt. 2008, 47, 4965.
G. Zonios, A. Dimou, Biomed. Opt. Exp. 2011, 2, 3284.
Y. Zhang, S. Yu, X. Zhu, X. Ning, W. Liu, C. Wang, X. Liu, D. Zhao, Y. Zheng, J. Bao, Biomed. Opt. Exp. 2021, 12, 4510.
M. S. Safi, S. M. M. Safi, Biomed. Sig. Proc. Control 2021, 65, 102338.
Z. Deng, B. W. He, C. S. Zou, J. Wu, Z. J. Zhu, Biomed. Sig. Proc. Control 2022, 71(Part-B), 103235.
D. J. Mitra, M. Shahjalal, M. A. Kiber, Int. J. Eng. Comp. Sci. 2014, 3, 7605.
M. AlMahamdy, H. B. Riley, Proc. Comp. Sci. 2014, 37, 325.
X. U. Zhang, D. J. Faber, A. L. Post, T. G. van Leeuwen, H. J. C. M. Sterenborg, J. Biophotonics 2019, 12, e201900019.
A. N. Bashkatov, E. A. Genina1, V. I. Kochubey, V. V. Tuchin, J. Phys. D: Appl. Phys. 2005, 38, 2543.
G. Zonios, A. Dimou, Opt. Exp. 2009, 17, 1256.
X. Wang, B. W. Pogue, S. Jiang, X. Song, K. D. Paulsen, C. Kogel, S. P. Poplack, W. A. Wells, J. Biomed. Opt. 2005, 10, 051704.
J. D. Rogers, A. J. Radosevich, J. Yi, V. Backman, IEEE. J. Sel. Top. Quantum. Electron. 2013, 20, 7000514.
X. Wang, B. W. Pogue, S. Jiang, H. Dehghani, X. Song, S. Srinivasan, B. A. Brooksby, K. D. Paulsen, C. Kogel, S. P. Poplack, W. A. Wells, J. Biomed. Opt. 2006, 11, 041106.
V. Tuchin, Tissue Optics: Light Scattering Methods and Instruments for Medical Diagnosis, 2nd ed., SPIE Press, Bellingham, Washington USA. 2007.
L. A. Courtenay, et. al. "," Biomed. Opt. Exp. 12(8), 5107-5127 (2021).
B. Fei, G. Lu, X. Wang, H. Zhang, J. V. Little, M. R. Patel, C. C. Griffith, M. W. El-Diery, A. Y. Chen, J. Biomed. Opt. 2017, 22, 086009.
M. A. Calin, S. V. Parasca, J. Biophotonics 2022, 15, e202100231.
D. Eggert, M. Bengs, S. Westermann, N. Gessert, A. O. H. Gerstner, N. A. Mueller, J. Bewarder, A. Schlaefer, C. Betz, W. Laffers, J. Biophotonics 2022, 15, e202100167.
T.-N. Luu, Q.-H. Phan, T.-H. Le, T.-T.-H. Pham, Optik 2022, 249, 168239.
B. S. A. Gazioğlu, M. E. Kamaşak, Biomed. Sig. Proc. Cont. 2021, 67, 102530.
S. C. Kanick, D. J. Robinson, H. J. C. M. Sterenborg, A. Amelink, Opt. Lett. 2011, 36, 2791.
F. Bevilacqua, A. J. Berger, A. E. Cerussi, D. Jakubowski, B. J. Tromberg, Appl. Opt. 2000, 39, 6498.