Incidence of Underlying Abnormal Findings on Routine Magnetic Resonance Imaging for Bell Palsy.


Journal

JAMA network open
ISSN: 2574-3805
Titre abrégé: JAMA Netw Open
Pays: United States
ID NLM: 101729235

Informations de publication

Date de publication:
03 04 2023
Historique:
medline: 24 4 2023
pubmed: 20 4 2023
entrez: 20 04 2023
Statut: epublish

Résumé

There is no consensus on the benefits of routine magnetic resonance imaging (MRI) of the facial nerve in patients with suspected idiopathic peripheral facial palsy (PFP) (ie, Bell palsy [BP]). To estimate the proportion of adult patients in whom MRI led to correction of an initial clinical diagnosis of BP; to determine the proportion of patients with confirmed BP who had MRI evidence of facial nerve neuritis without secondary lesions; and to identify factors associated with secondary (nonidiopathic) PFP at initial presentation and 1 month later. This retrospective multicenter cohort study analyzed the clinical and radiological data of 120 patients initially diagnosed with suspected BP from January 1, 2018, to April 30, 2022, at the emergency department of 3 tertiary referral centers in France. All patients screened for clinically suspected BP underwent an MRI of the entire facial nerve with a double-blind reading of all images. The proportion of patients in whom MRI led to a correction of the initial diagnosis of BP (any condition other than BP, including potentially life-threating conditions) and results of contrast enhancement of the facial nerve were described. Among the 120 patients initially diagnosed with suspected BP, 64 (53.3%) were men, and the mean (SD) age was 51 (18) years. Magnetic resonance imaging of the facial nerve led to a correction of the diagnosis in 8 patients (6.7%); among them, potentially life-threatening conditions that required changes in treatment were identified in 3 (37.5%). The MRI confirmed the diagnosis of BP in 112 patients (93.3%), among whom 106 (94.6%) showed evidence of facial nerve neuritis on the affected side (hypersignal on gadolinium-enhanced T1-weighted images). This was the only objective sign confirming the idiopathic nature of PFP. These preliminary results suggest the added value of the routine use of facial nerve MRI in suspected cases of BP. Multicentered international prospective studies should be organized to confirm these results.

Identifiants

pubmed: 37079301
pii: 2803956
doi: 10.1001/jamanetworkopen.2023.9158
pmc: PMC10119737
doi:

Types de publication

Multicenter Study Randomized Controlled Trial Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e239158

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Auteurs

Thibault Savary (T)

Service d'ORL, d'Otoneurochirurgie et de Chirurgie Cervico-Faciale, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Pierre Bénite, France.

Maxime Fieux (M)

Service d'ORL, d'Otoneurochirurgie et de Chirurgie Cervico-Faciale, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Pierre Bénite, France.
Université de Lyon, Université Lyon 1, Lyon, France.
Université Paris Est Créteil, Institut National de la Santé et de la Recherche Médicale (INSERM), Mondor Institute for Biomedical Research (IMRB), Créteil, France.
Centre National de la Recherche Scientifique (CNRS) Equipe Mixte de Recherche 7000, Créteil, France.

Marion Douplat (M)

Université de Lyon, Université Lyon 1, Lyon, France.
Service des Urgences, Hospices Civils of Lyon, Centre Hospitalier Lyon Sud, Pierre Bénite, France.
Research on Healthcare Performance, Université Claude Bernard Lyon 1, INSERM U1290, Lyon, France.
Unité Mixte de Recherche (UMR) Adés 7268, Aix-Marseille University, Etablissement Français du Sang-CNRS, Espace Éthique Méditerranéen, Marseille, France.

Romain Tournegros (R)

Service d'ORL, d'Otoneurochirurgie et de Chirurgie Cervico-Faciale, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Pierre Bénite, France.

Sophie Daubie (S)

Service d'Imagerie Médicale, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Pierre Bénite, France.

Dylan Pavie (D)

Service d'Imagerie Médicale, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Pierre Bénite, France.

Luna Denoix (L)

Service d'ORL, d'Otoneurochirurgie et de Chirurgie Cervico-Faciale, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Pierre Bénite, France.

Jean-Baptiste Pialat (JB)

Université de Lyon, Université Lyon 1, Lyon, France.
Service d'Imagerie Médicale, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Pierre Bénite, France.
Creatis CNRS UMR 5220, INSERM U1294, Université Lyon 1, Villeurbanne, France.

Stephane Tringali (S)

Service d'ORL, d'Otoneurochirurgie et de Chirurgie Cervico-Faciale, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Pierre Bénite, France.
Université de Lyon, Université Lyon 1, Lyon, France.
UMR 5305, Laboratoire de Biologie Tissulaire et d'Ingénierie Thérapeutique, Institut de Biologie et Chimie des Protéines, CNRS Université Claude Bernard Lyon 1, Lyon, France.

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Classifications MeSH