Flexor Tendon Adhesion Formation: Current Concepts.

Animals Humans Tendon Injuries / surgery Tendons / surgery Wound Healing Tissue Adhesions / prevention & control Cytokines
Biomaterials Hydrogel Lubricin PXL01 TGF-Beta Tendon adhesion Tendon injury Tendon repair

Journal

Hand clinics
ISSN: 1558-1969
Titre abrégé: Hand Clin
Pays: United States
ID NLM: 8510415

Informations de publication

Date de publication:
05 2023
Historique:
medline: 24 4 2023
pubmed: 21 4 2023
entrez: 20 04 2023
Statut: ppublish

Résumé

Over the years, various physical and chemical/biological methods of inhibiting adhesion formation have been developed, focusing on how to suppress healing around the tendon and not inhibit healing within the tendon. Unfortunately, however, these methods are accompanied by drawbacks, both large and small, and no absolute antiadhesion method capable of maintaining tendon repair strength has yet been developed. Recent innovations in biomaterials science and tissue engineering have produced new antiadhesion technologies, such as barriers combined with cytokines and cells, which have improved outcomes in animal models, and which may find clinical relevance in the future.

Identifiants

DOI: 10.1016/j.hcl.2022.08.018 PMID: 37080649
pubmed: 37080649
pii: S0749-0712(22)00076-2
doi: 10.1016/j.hcl.2022.08.018
pii:
doi:

Substances chimiques

Cytokines 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

171-180

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Auteurs

Tomoyuki Kuroiwa (T)

Department of Orthopedic Surgery, Mayo Clinic, 200 First St. SW, Rochester, MN, USA.

Peter C Amadio (PC)

Department of Orthopedic Surgery, Mayo Clinic, 200 First St. SW, Rochester, MN, USA. Electronic address: pamadio@mayo.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Flexor Tendon Adhesion Formation: Current Concepts.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Flexor Tendon Adhesion Formation: Current Concepts.
questionsmedicales.fr › Plaies et blessures › Traumatismes des tendons › Flexor Tendon Adhesion Formation: Current Concepts.
questionsmedicales.fr › Appareil locomoteur › Tendons › Flexor Tendon Adhesion Formation: Current Concepts.
questionsmedicales.fr › Phénomènes biologiques › Régénération › Cicatrisation de plaie › Flexor Tendon Adhesion Formation: Current Concepts.
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Fibrose › Adhérences tissulaires › Flexor Tendon Adhesion Formation: Current Concepts.
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Flexor Tendon Adhesion Formation: Current Concepts.