Acute Viral Bronchiolitis: A Narrative Review.

HFNC hypertonic saline nebulization respiratory syncytial virus wheezing

Journal

Journal of pediatric intensive care
ISSN: 2146-4618
Titre abrégé: J Pediatr Intensive Care
Pays: Germany
ID NLM: 101592756

Informations de publication

Date de publication:
Jun 2023
Historique:
received: 06 06 2020
accepted: 09 07 2020
medline: 2 9 2020
pubmed: 2 9 2020
entrez: 21 04 2023
Statut: epublish

Résumé

Acute viral bronchiolitis (AVB) is the leading cause of hospital admissions among infants in developed and developing countries and associated with increased morbidity and cost of treatment. This review was performed to guide the clinicians managing AVB in light of evidence accumulated in the last decade. We searched published English literature in last decade regarding etiology, diagnosis, treatment, and prevention of AVB using PubMed and Cochrane Database of Systematic Reviews. Respiratory syncytial virus is the most common causative agent. The diagnosis is mainly clinical with limited role of diagnostic investigations and chest radiographs are not routinely indicated. The management of AVB remains a challenge, as the role of various interventions is not clear. Supportive care in form of provision of heated and humidified oxygen and maintaining hydration are main interventions. The use of pulse oximetry helps to guide the administration of oxygen. Trials and systematic reviews evaluated various interventions like nebulized adrenaline, bronchodilators and hypertonic saline, corticosteroids, different modes of noninvasive ventilation (high-flow nasal cannula [HFNC], continuous positive airway pressure [CPAP], and noninvasive positive pressure ventilation [NPPV]), surfactant, heliox, chest physiotherapy, and antiviral drugs. The interventions which showed some benefits in infants and children with AVB are adrenaline and hypertonic saline nebulization, HFNC, CPAP, NIV, and surfactant. The routine administration of antibiotics, bronchodilators, corticosteroids, steam inhalation, chest physiotherapy, heliox, and antiviral drugs are not recommended.

Identifiants

DOI: 10.1055/s-0040-1715852 PMID: 37082471 PMC: PMC10113010
pubmed: 37082471
doi: 10.1055/s-0040-1715852
pii: 2000088
pmc: PMC10113010
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

79-86

Informations de copyright

Thieme. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of Interest None declared.

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Auteurs

Suresh K Angurana (SK)

Division of Pediatric Critical Care, Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Vijai Williams (V)

Pediatric Intensive Care Unit, Gleneagles Global Hospitals, Perumbakkam, Chennai, India.

Lalit Takia (L)

Division of Pediatric Critical Care, Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Classifications MeSH