Responses of hepatic sinusoidal cells to liver ischemia-reperfusion injury.
endothelial cells
ischemia-reperfusion
liver repair
macrophage
stellate cell
Journal
Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250
Informations de publication
Date de publication:
2023
2023
Historique:
received:
22
02
2023
accepted:
27
03
2023
medline:
21
4
2023
pubmed:
21
4
2023
entrez:
21
04
2023
Statut:
epublish
Résumé
The liver displays a remarkable regenerative capacity in response to acute liver injury. In addition to the proliferation of hepatocytes during liver regeneration, non-parenchymal cells, including liver macrophages, liver sinusoidal endothelial cells (LSECs), and hepatic stellate cells (HSCs) play critical roles in liver repair and regeneration. Liver ischemia-reperfusion injury (IRI) is a major cause of increased liver damage during liver resection, transplantation, and trauma. Impaired liver repair increases postoperative morbidity and mortality of patients who underwent liver surgery. Successful liver repair and regeneration after liver IRI requires coordinated interplay and synergic actions between hepatic resident cells and recruited cell components. However, the underlying mechanisms of liver repair after liver IRI are not well understood. Recent technological advances have revealed the heterogeneity of each liver cell component in the steady state and diseased livers. In this review, we describe the progress in the biology of liver non-parenchymal cells obtained from novel technological advances. We address the functional role of each cell component in response to liver IRI and the interactions between diverse immune repertoires and non-hematopoietic cell populations during the course of liver repair after liver IRI. We also discuss how these findings can help in the design of novel therapeutic approaches. Growing insights into the cellular interactions during liver IRI would enhance the pathology of liver IRI understanding comprehensively and further develop the strategies for improvement of liver repair.
Identifiants
pubmed: 37082623
doi: 10.3389/fcell.2023.1171317
pii: 1171317
pmc: PMC10112669
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
1171317Informations de copyright
Copyright © 2023 Ito, Hosono and Amano.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
J Hepatol. 2022 Apr;76(4):896-909
pubmed: 34871625
Cell Rep. 2015 Dec 1;13(9):1757-64
pubmed: 26655896
Immunity. 2019 Oct 15;51(4):638-654.e9
pubmed: 31561945
HPB (Oxford). 2019 Sep;21(9):1139-1149
pubmed: 30718185
Front Immunol. 2018 Dec 14;9:2948
pubmed: 30619308
Cell Death Dis. 2020 Apr 17;11(4):244
pubmed: 32303674
Hepatology. 2021 Aug;74(2):667-685
pubmed: 33550587
Am J Physiol Gastrointest Liver Physiol. 2020 Mar 1;318(3):G390-G400
pubmed: 31961717
Nat Rev Gastroenterol Hepatol. 2018 Sep;15(9):555-567
pubmed: 29844586
Nat Rev Immunol. 2020 Apr;20(4):254-267
pubmed: 31822793
Nat Rev Immunol. 2010 Jun;10(6):427-39
pubmed: 20498669
Hepatology. 2023 Feb 1;77(2):443-455
pubmed: 35603471
Front Physiol. 2021 Oct 11;12:757469
pubmed: 34707514
Angiogenesis. 2020 Aug;23(3):395-410
pubmed: 32162023
Hepatology. 2016 Nov;64(5):1667-1682
pubmed: 27302828
PLoS One. 2017 Sep 28;12(9):e0184752
pubmed: 28957350
Front Immunol. 2021 Feb 08;11:616044
pubmed: 33628208
Immunity. 2013 Apr 18;38(4):792-804
pubmed: 23601688
J Clin Invest. 2019 Jul 11;129(10):4091-4109
pubmed: 31295147
Hepatology. 1996 Nov;24(5):1193-8
pubmed: 8903397
Immunity. 2020 Jun 16;52(6):1057-1074.e7
pubmed: 32362324
Gastroenterology. 2016 Dec;151(6):1176-1191
pubmed: 27569723
J Hepatol. 2022 Oct;77(4):1136-1160
pubmed: 35750137
Am J Transplant. 2018 May;18(5):1110-1121
pubmed: 29136322
Front Immunol. 2019 Dec 03;10:2852
pubmed: 31849997
Hepatology. 2014 Oct;60(4):1356-66
pubmed: 24623351
Cell Rep. 2021 Jan 12;34(2):108626
pubmed: 33440159
Nat Commun. 2016 Jan 27;7:10321
pubmed: 26813785
Front Immunol. 2017 Jun 01;8:626
pubmed: 28620383
Immunity. 2013 Jan 24;38(1):79-91
pubmed: 23273845
Am J Physiol Gastrointest Liver Physiol. 2016 Aug 1;311(2):G246-51
pubmed: 27288423
PLoS Biol. 2005 Apr;3(4):e113
pubmed: 15799695
Immunity. 2021 Sep 14;54(9):2101-2116.e6
pubmed: 34469775
Front Cell Dev Biol. 2022 Aug 16;10:949896
pubmed: 36051444
Immunity. 2019 Oct 15;51(4):655-670.e8
pubmed: 31587991
Cell Stem Cell. 2022 Jun 2;29(6):973-989.e10
pubmed: 35659879
J Hepatol. 2014 Feb;60(2):298-305
pubmed: 24060854
Semin Liver Dis. 2019 Nov;39(4):442-451
pubmed: 31242527
Science. 2017 Oct 6;358(6359):111-116
pubmed: 28983053
Immunity. 2018 Oct 16;49(4):666-677.e6
pubmed: 30291029
Gastroenterology. 2003 Oct;125(4):1246-57
pubmed: 14517806
J Exp Med. 2007 Nov 26;204(12):3037-47
pubmed: 18025128
J Hepatol. 2018 Jul;69(1):110-120
pubmed: 29458169
Front Immunol. 2021 Jun 09;12:690813
pubmed: 34177948
Hepatology. 2021 Oct;74(4):2118-2132
pubmed: 33999437
J Clin Invest. 2022 May 2;132(9):
pubmed: 35271504
Front Immunol. 2021 Jun 21;12:697362
pubmed: 34234785
Am J Physiol Gastrointest Liver Physiol. 2003 Jan;284(1):G15-26
pubmed: 12488232
Science. 2012 Apr 6;336(6077):86-90
pubmed: 22442384
Front Immunol. 2018 Sep 07;9:1930
pubmed: 30245686
Front Immunol. 2020 Jun 26;11:1193
pubmed: 32676077
Trends Immunol. 2011 Aug;32(8):350-7
pubmed: 21782511
Annu Rev Cell Dev Biol. 2011;27:563-84
pubmed: 21756109
Metallomics. 2014 Aug;6(8):1336-45
pubmed: 24905850
Toxicol Appl Pharmacol. 2016 Oct 1;308:1-10
pubmed: 27521978
Gut. 2020 Mar;69(3):551-563
pubmed: 31076404
Cell Mol Gastroenterol Hepatol. 2021;11(2):573-595
pubmed: 32961356
Hepatology. 2012 Mar;55(3):921-30
pubmed: 22031447
Immunity. 2017 Oct 17;47(4):752-765.e5
pubmed: 29045904
Mol Med. 2015 Mar 13;20:639-48
pubmed: 25375408
Nature. 2019 Nov;575(7783):512-518
pubmed: 31597160
Am J Transplant. 2017 Jan;17(1):69-80
pubmed: 27467205
Gastroenterology. 2015 Dec;149(7):1896-1909.e14
pubmed: 26344055
Elife. 2021 Jun 10;10:
pubmed: 34110284
Blood. 2015 Apr 23;125(17):2605-13
pubmed: 25762175
Cell Mol Gastroenterol Hepatol. 2022;13(6):1741-1756
pubmed: 35114417
Cell Rep. 2019 Nov 12;29(7):1832-1847.e8
pubmed: 31722201
Cytokine Growth Factor Rev. 2012 Jun;23(3):69-84
pubmed: 22609105
Nat Rev Gastroenterol Hepatol. 2017 Jul;14(7):397-411
pubmed: 28487545
Cell. 2016 Apr 21;165(3):668-78
pubmed: 27062926
J Exp Med. 2015 Apr 6;212(4):447-56
pubmed: 25800956
Immunity. 2018 Jan 16;48(1):35-44.e6
pubmed: 29195811
Immunity. 2020 Mar 17;52(3):434-451
pubmed: 32187515
Trends Biochem Sci. 2017 Apr;42(4):245-254
pubmed: 27932073
J Immunol. 2014 Jul 1;193(1):344-53
pubmed: 24890723
J Hepatol. 2022 Jul;77(1):206-218
pubmed: 35157960
J Clin Invest. 2021 Oct 15;131(20):
pubmed: 34403369
Gastroenterology. 2007 Aug;133(2):632-46
pubmed: 17681182
Toxicol Lett. 2020 Dec 15;335:71-81
pubmed: 33122006
J Hepatol. 2016 Oct;65(4):758-768
pubmed: 27262757
Nat Biotechnol. 2018 Nov;36(10):962-970
pubmed: 30222169
Front Immunol. 2019 Nov 19;10:2694
pubmed: 31803196
Immunity. 2015 Jan 20;42(1):145-58
pubmed: 25577440
Cell. 2006 Mar 10;124(5):915-27
pubmed: 16530040
FASEB J. 1990 Dec;4(15):3355-9
pubmed: 2253850
Nature. 2017 Feb 16;542(7641):352-356
pubmed: 28166538
Toxicol Sci. 2011 Mar;120(1):218-29
pubmed: 21135413
Nat Med. 2016 Aug;22(8):945-51
pubmed: 27428900
Cell. 2022 Jan 20;185(2):379-396.e38
pubmed: 35021063
J Hepatol. 2015 Oct;63(4):917-25
pubmed: 26022689
J Clin Invest. 2017 Aug 1;127(8):2904-2915
pubmed: 28650342
J Hepatol. 2020 Oct;73(4):757-770
pubmed: 32360434
Nat Rev Immunol. 2018 Sep;18(9):559-574
pubmed: 29967365
N Engl J Med. 2014 Jan 30;370(5):455-65
pubmed: 24476434
Dev Cell. 2021 Jun 7;56(11):1677-1693.e10
pubmed: 34038707
J Hepatol. 2019 Sep;71(3):553-562
pubmed: 31077791
Hepatology. 2018 Aug;68(2):707-722
pubmed: 29059455
Am J Pathol. 2019 Jul;189(7):1363-1374
pubmed: 31026418
Transplant Proc. 2010 Dec;42(10):4282-5
pubmed: 21168683
Scientifica (Cairo). 2012;2012:513192
pubmed: 24278708
Am J Physiol Gastrointest Liver Physiol. 2019 Mar 1;316(3):G323-G331
pubmed: 30543462
Hepatology. 2014 Apr;59(4):1564-76
pubmed: 24282114
J Leukoc Biol. 2008 Dec;84(6):1410-21
pubmed: 18713872
World J Gastroenterol. 2022 Mar 7;28(9):897-908
pubmed: 35317052
Hepatology. 2016 May;63(5):1689-705
pubmed: 26573873
Gastroenterology. 2009 Aug;137(2):704-12
pubmed: 19447108
Front Immunol. 2021 Dec 03;12:786680
pubmed: 34925367
Immunity. 2022 Sep 13;55(9):1515-1529
pubmed: 36103850
Cell Rep Med. 2022 Oct 18;3(10):100754
pubmed: 36220068
Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):E3186-95
pubmed: 23100531
Front Immunol. 2020 Apr 17;11:322
pubmed: 32362892
Cell Mol Immunol. 2021 Jan;18(1):45-56
pubmed: 33041338
Hepatol Int. 2019 Nov;13(6):777-787
pubmed: 31515741
Science. 2017 Jun 9;356(6342):1072-1076
pubmed: 28495875
Nat Rev Gastroenterol Hepatol. 2022 Apr;19(4):239-256
pubmed: 34837066
Curr Transplant Rep. 2019;6(1):78-89
pubmed: 31602356
Nat Commun. 2019 Mar 6;10(1):1076
pubmed: 30842418
J Immunol. 2017 May 1;198(9):3588-3595
pubmed: 28289160
J Clin Invest. 2021 Feb 15;131(4):
pubmed: 33320839
Nat Commun. 2018 Oct 22;9(1):4383
pubmed: 30348985
Hepatology. 2010 Feb;51(2):621-32
pubmed: 19902481
Front Immunol. 2022 Oct 27;13:1037645
pubmed: 36389830
Liver Transpl. 2014 Nov;20(11):1372-82
pubmed: 25046819
Front Immunol. 2021 Oct 06;12:754106
pubmed: 34691073
Nat Rev Gastroenterol Hepatol. 2013 Feb;10(2):79-89
pubmed: 23229329
Mol Ther. 2009 Jan;17(1):65-72
pubmed: 19002167
Cell Stem Cell. 2018 Mar 1;22(3):384-397.e6
pubmed: 29429943
Eur J Immunol. 2019 Jun;49(6):831-841
pubmed: 31001813
Front Immunol. 2022 Sep 30;13:994480
pubmed: 36248843
Eur Heart J. 2017 Jan 14;38(3):187-197
pubmed: 28158426
Hepatology. 2015 Jul;62(1):253-64
pubmed: 25783863
Toxicol Appl Pharmacol. 2014 Mar 1;275(2):122-33
pubmed: 24440789
Nature. 2015 Feb 26;518(7540):547-51
pubmed: 25470051
Immunity. 2020 Sep 15;53(3):641-657.e14
pubmed: 32888418
J Immunol. 2014 Apr 15;192(8):3847-3857
pubmed: 24639359
Dev Cell. 2021 Nov 22;56(22):3042-3051
pubmed: 34813766
Curr Opin Immunol. 2007 Jun;19(3):354-64
pubmed: 17428648
Nat Med. 2019 Oct;25(10):1560-1565
pubmed: 31591593
Circulation. 2016 Apr 12;133(15):1484-97; discussion 1497
pubmed: 26933083
Hepatology. 2020 Nov;72(5):1771-1785
pubmed: 32060938
Anat Rec (Hoboken). 2008 Jun;291(6):661-71
pubmed: 18484612
JCI Insight. 2018 Oct 4;3(19):
pubmed: 30282830
J Hepatol. 2020 Aug;73(2):349-360
pubmed: 32169610
Immunity. 2017 Aug 15;47(2):374-388.e6
pubmed: 28813662
Circ Res. 2012 Sep 28;111(8):1037-47
pubmed: 22887770
J Hepatol. 2018 Apr;68(4):682-690
pubmed: 29274730
Am J Transplant. 2020 Jun;20(6):1606-1618
pubmed: 31909544
Nature. 2019 Aug;572(7768):199-204
pubmed: 31292543
J Immunol. 2010 May 15;184(10):5849-58
pubmed: 20400698
J Hepatol. 2015 Nov;63(5):1263-71
pubmed: 26169159
Front Immunol. 2022 Jul 29;13:869365
pubmed: 35967407
Am J Physiol Gastrointest Liver Physiol. 2016 May 1;310(9):G739-46
pubmed: 26939868
J Hepatol. 2013 Dec;59(6):1200-7
pubmed: 23867319
Hepatol Commun. 2018 Jun 21;2(7):845-860
pubmed: 30027142
Nature. 2021 Jan;589(7840):131-136
pubmed: 33239787
Am J Pathol. 1997 Jul;151(1):169-75
pubmed: 9212743
Gut. 2018 Feb;67(2):333-347
pubmed: 28450389
Immunity. 2020 Sep 15;53(3):627-640.e5
pubmed: 32562600
J Exp Med. 2005 Apr 4;201(7):1135-43
pubmed: 15795240
Hepatology. 2022 Oct;76(4):1219-1230
pubmed: 35175659
FASEB J. 2013 Aug;27(8):3132-43
pubmed: 23629862
Gastroenterology. 2016 Dec;151(6):1087-1095
pubmed: 27725145
Immunity. 2015 Apr 21;42(4):665-78
pubmed: 25902481
JCI Insight. 2023 Jan 10;8(1):
pubmed: 36422999
Nature. 2022 Oct;610(7931):356-365
pubmed: 36198802
Cell. 2012 May 25;149(5):1060-72
pubmed: 22632970
Nat Rev Immunol. 2017 May;17(5):306-321
pubmed: 28317925
J Clin Invest. 2012 Apr;122(4):1567-73
pubmed: 22406533
Semin Liver Dis. 2018 Nov;38(4):340-350
pubmed: 30357771
PLoS One. 2014 Aug 27;9(8):e105533
pubmed: 25162491