Normal Values of Three-Dimensional Right Ventricular Size and Function Measurements: Results of the World Alliance Societies of Echocardiography Study.


Journal

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
ISSN: 1097-6795
Titre abrégé: J Am Soc Echocardiogr
Pays: United States
ID NLM: 8801388

Informations de publication

Date de publication:
08 2023
Historique:
received: 19 09 2022
revised: 10 04 2023
accepted: 11 04 2023
medline: 7 8 2023
pubmed: 22 4 2023
entrez: 21 04 2023
Statut: ppublish

Résumé

Normal values for three-dimensional (3D) right ventricular (RV) size and function are not well established, as they originate from small studies that involved predominantly white North American and European populations, did not use RV-focused views, and relied on older 3D RV analysis software. The World Alliance Societies of Echocardiography study was designed to generate reference ranges for normal subjects around the world. The aim of this study was to assess the worldwide capability of 3D imaging of the right ventricle and report size and function measurements, including their dependency on age, sex, and ethnicity. Healthy subjects free of cardiac, pulmonary, and renal disease were prospectively enrolled at 19 centers in 15 countries, representing six continents. Three-dimensional wide-angle RV data sets were obtained and analyzed using dedicated RV software (TomTec) to measure end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume, and ejection fraction (EF). Results were categorized by sex, age (18-40, 41-65, and >65 years) and ethnicity. Of the 2,007 subjects with attempted 3D RV acquisitions, 1,051 had adequate image quality for confident measurements. Upper and lower limits for body surface area-indexed EDV, ESV, and EF were 48 and 95 mL/m Reliability of 3D RV acquisition is low worldwide, underscoring the importance of future improvements in imaging techniques. Sex and race must be taken into consideration in the assessment of both RV volumes and EF.

Sections du résumé

BACKGROUND
Normal values for three-dimensional (3D) right ventricular (RV) size and function are not well established, as they originate from small studies that involved predominantly white North American and European populations, did not use RV-focused views, and relied on older 3D RV analysis software. The World Alliance Societies of Echocardiography study was designed to generate reference ranges for normal subjects around the world. The aim of this study was to assess the worldwide capability of 3D imaging of the right ventricle and report size and function measurements, including their dependency on age, sex, and ethnicity.
METHODS
Healthy subjects free of cardiac, pulmonary, and renal disease were prospectively enrolled at 19 centers in 15 countries, representing six continents. Three-dimensional wide-angle RV data sets were obtained and analyzed using dedicated RV software (TomTec) to measure end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume, and ejection fraction (EF). Results were categorized by sex, age (18-40, 41-65, and >65 years) and ethnicity.
RESULTS
Of the 2,007 subjects with attempted 3D RV acquisitions, 1,051 had adequate image quality for confident measurements. Upper and lower limits for body surface area-indexed EDV, ESV, and EF were 48 and 95 mL/m
CONCLUSIONS
Reliability of 3D RV acquisition is low worldwide, underscoring the importance of future improvements in imaging techniques. Sex and race must be taken into consideration in the assessment of both RV volumes and EF.

Identifiants

pubmed: 37085129
pii: S0894-7317(23)00203-1
doi: 10.1016/j.echo.2023.04.011
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

858-866.e1

Investigateurs

Aldo D Prado (AD)
Eduardo Filipini (E)
Agatha Kwon (A)
Samantha Hoschke-Edwards (S)
Tania Regina Afonso (TR)
Babitha Thampinathan (B)
Maala Sooriyakanthan (M)
Tiangang Zhu (T)
Zhilong Wang (Z)
Yingbin Wang (Y)
Lixue Yin (L)
Shuang Li (S)
R Alagesan (R)
S Balasubramanian (S)
R V A Ananth (RVA)
Manish Bansal (M)
Luigi Badano (L)
Eduardo Bossone (E)
Davide Di Vece (D)
Michele Bellino (M)
Tomoko Nakao (T)
Takayuki Kawata (T)
Megumi Hirokawa (M)
Naoko Sawada (N)
Yousuke Nabeshima (Y)
Hye Rim Yun (HR)
Ji-Won Hwang (JW)

Informations de copyright

Copyright © 2023 American Society of Echocardiography. Published by Elsevier Inc. All rights reserved.

Auteurs

Karima Addetia (K)

University of Chicago, Chicago, Illinois.

Tatsuya Miyoshi (T)

MedStar Health Research Institute, Washington, District of Columbia.

Vivekanandan Amuthan (V)

Jeyalakshmi Heart Center, Madurai, India.

Rodolfo Citro (R)

University Hospital "San Giovanni di Dio e Ruggi d'Aragona", Salerno, Italy; RCCS Neuromed, Pozzilli, Italy.

Masao Daimon (M)

University of Tokyo, Tokyo, Japan.

Pedro Gutierrez Fajardo (P)

Hospital Bernardette, Guadalajara, Mexico.

Ravi R Kasliwal (RR)

Medanta Medicity, Gurgaon, India.

James N Kirkpatrick (JN)

University of Washington, Seattle, Washington.

Mark J Monaghan (MJ)

King's College Hospital, London, United Kingdom.

Denisa Muraru (D)

University of Milano-Bicocca and Istituto Auxologico Italiano, IRCCS, Milan, Italy.

Kofo O Ogunyankin (KO)

First Cardiology Consultants, Hospital Ikoyi, Lagos, Nigeria.

Seung Woo Park (SW)

Samsung Medical Center/Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Ricardo E Ronderos (RE)

Instituto Cardiovascular de Buenos Aires, Buenos Aires, Argentina.

Anita Sadeghpour (A)

Rajaie Cardiovascular Medical Center, Iran University of Medical Sciences, Tehran, Iran.

Gregory M Scalia (GM)

GenesisCare, Brisbane, Australia.

Masaaki Takeuchi (M)

University of Occupational and Environmental Health, Kitakyushu, Japan.

Wendy Tsang (W)

Toronto General Hospital/University of Toronto, Toronto, Ontario, Canada.

Edwin S Tucay (ES)

Philippine Heart Center, Quezon City, Philippines.

Ana Clara Tude Rodrigues (AC)

Hospital Israelita Albert Einstein, São Paulo, Brazil.

Yun Zhang (Y)

Qilu Hospital of Shandong University, Jinan, China.

Cristiane C Singulane (CC)

University of Chicago, Chicago, Illinois.

Niklas Hitschrich (N)

TomTec Imaging Systems, Unterschleissheim, Germany.

Michael Blankenhagen (M)

TomTec Imaging Systems, Unterschleissheim, Germany.

Markus Degel (M)

TomTec Imaging Systems, Unterschleissheim, Germany.

Marcus Schreckenberg (M)

TomTec Imaging Systems, Unterschleissheim, Germany.

Victor Mor-Avi (V)

University of Chicago, Chicago, Illinois.

Federico M Asch (FM)

MedStar Health Research Institute, Washington, District of Columbia.

Roberto M Lang (RM)

University of Chicago, Chicago, Illinois. Electronic address: rlang@medicine.bsd.uchicago.edu.

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