Associations between cardiovascular risk factors, disease activity and cardiorespiratory fitness in patients with inflammatory joint disease: a cross-sectional analysis.

(MESH terms) Cardiorespiratory fitness Cardiovascular diseases Rheumatoid arthritis Spondyloarthritis

Journal

BMC sports science, medicine & rehabilitation
ISSN: 2052-1847
Titre abrégé: BMC Sports Sci Med Rehabil
Pays: England
ID NLM: 101605016

Informations de publication

Date de publication:
21 Apr 2023
Historique:
received: 10 02 2023
accepted: 19 04 2023
medline: 22 4 2023
pubmed: 22 4 2023
entrez: 21 04 2023
Statut: epublish

Résumé

Inflammatory joint diseases (IJD) are accompanied by an increased risk of cardiovascular disease (CVD). Cardiorespiratory fitness (CRF) is a modifiable CVD risk factor and low levels of CRF associate with an elevated CVD risk. This study aimed to investigate the associations between CVD risk factors, disease activity and CRF in patients with IJD and to explore differences between patients with normal versus low levels of CRF. CRF was measured as peak oxygen uptake (VO In 60 Norwegian patients with IJD [34 females, age 59 years (IQR: 52-63)], mean VO In this sample of IJD-patients, age, fatmass and physical activity level were associated with CRF. CRF was lower than reference values and patients with normal CRF presented with a more favorable health profile. There is a continued need for exercise interventions to improve CRF in patients with IJD. NCT04922840.

Sections du résumé

BACKGROUND BACKGROUND
Inflammatory joint diseases (IJD) are accompanied by an increased risk of cardiovascular disease (CVD). Cardiorespiratory fitness (CRF) is a modifiable CVD risk factor and low levels of CRF associate with an elevated CVD risk. This study aimed to investigate the associations between CVD risk factors, disease activity and CRF in patients with IJD and to explore differences between patients with normal versus low levels of CRF.
METHODS METHODS
CRF was measured as peak oxygen uptake (VO
RESULTS RESULTS
In 60 Norwegian patients with IJD [34 females, age 59 years (IQR: 52-63)], mean VO
CONCLUSIONS CONCLUSIONS
In this sample of IJD-patients, age, fatmass and physical activity level were associated with CRF. CRF was lower than reference values and patients with normal CRF presented with a more favorable health profile. There is a continued need for exercise interventions to improve CRF in patients with IJD.
TRIAL REGISTRATION BACKGROUND
NCT04922840.

Identifiants

pubmed: 37085935
doi: 10.1186/s13102-023-00678-4
pii: 10.1186/s13102-023-00678-4
pmc: PMC10120183
doi:

Banques de données

ClinicalTrials.gov
['NCT04922840']

Types de publication

Journal Article

Langues

eng

Pagination

63

Subventions

Organisme : EkstraStiftelsen Helse og Rehabilitering (Stiftelsen Dam)
ID : 2021/FO347439
Organisme : REMEDY - Center for treatment of Rheumatic and Musculoskeletal Diseases
ID : 328657
Organisme : REMEDY - Center for treatment of Rheumatic and Musculoskeletal Diseases
ID : 328657
Organisme : REMEDY - Center for treatment of Rheumatic and Musculoskeletal Diseases
ID : 328657
Organisme : REMEDY - Center for treatment of Rheumatic and Musculoskeletal Diseases
ID : 328657
Organisme : REMEDY - Center for treatment of Rheumatic and Musculoskeletal Diseases
ID : 328657
Organisme : REMEDY - Center for treatment of Rheumatic and Musculoskeletal Diseases
ID : 328657
Organisme : REMEDY - Center for treatment of Rheumatic and Musculoskeletal Diseases
ID : 328657
Organisme : REMEDY - Center for treatment of Rheumatic and Musculoskeletal Diseases
ID : 328657
Organisme : Norsk Revmatikerforbund
ID : November 2021, no grant number
Organisme : Norsk Revmatikerforbund
ID : November 2021, no grant number

Informations de copyright

© 2023. The Author(s).

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Auteurs

Kristine Røren Nordén (KR)

Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Postboks 23, 0319, Vinderen, Oslo, Norway. kristineroren.norden@diakonsyk.no.
Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway. kristineroren.norden@diakonsyk.no.
Norwegian National Advisory Unit on Rehabilitation in Rheumatology, Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway. kristineroren.norden@diakonsyk.no.

Anne Grete Semb (AG)

The Preventive Cardio-Rheuma Clinic, Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.

Hanne Dagfinrud (H)

Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Postboks 23, 0319, Vinderen, Oslo, Norway.
Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway.
Norwegian National Advisory Unit on Rehabilitation in Rheumatology, Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway.

Jonny Hisdal (J)

Department of Vascular Surgery, Oslo University Hospital-Aker, Oslo, Norway.
Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.

Sigrid Ødegård (S)

Norwegian National Unit for Rehabilitation for Rheumatic Patients with Special Needs, Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway.

Joseph Sexton (J)

Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Postboks 23, 0319, Vinderen, Oslo, Norway.

Camilla Fongen (C)

Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Postboks 23, 0319, Vinderen, Oslo, Norway.
Norwegian National Advisory Unit on Rehabilitation in Rheumatology, Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway.

Jon Skandsen (J)

Patient Advisory Board, Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.

Thalita Blanck (T)

Patient Advisory Board, Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway.

George S Metsios (GS)

Department of Nutrition and Dietetics, University of Thessaly, Trikala, Thessaly, Greece.

Anne Therese Tveter (AT)

Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Postboks 23, 0319, Vinderen, Oslo, Norway.
Norwegian National Advisory Unit on Rehabilitation in Rheumatology, Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway.

Classifications MeSH