Molecular Assembly and Gelating Behavior of (l)-Alanine Derivatives.

(l)-amino acid chiral recognition low molecular weight organogelator self-assembly supermolecular gel

Journal

Chemistry (Weinheim an der Bergstrasse, Germany)
ISSN: 1521-3765
Titre abrégé: Chemistry
Pays: Germany
ID NLM: 9513783

Informations de publication

Date de publication:
11 Jul 2023
Historique:
received: 12 02 2023
medline: 22 4 2023
pubmed: 22 4 2023
entrez: 22 04 2023
Statut: ppublish

Résumé

In this study, a low-molecular-weight organogelator derived from (l)-amino acids was designed and synthesized. Gelation assays using (l)-amino acid derivatives were performed to confirm the gelation ability, which was found to be high in several compounds. The (l)-alanine derivatives were determined to be excellent gelators, forming good gels even when smaller amounts were added. These results led to a library of amino acid-derived organogelators. In addition, the thermal properties of the (l)-alanine derivatives with high gelation performance were measured. Differential scanning calorimetry measurements revealed that the thermal stability of the gels could be controlled by changing the gelator concentration. The surface states of the obtained gels were observed by field-emission scanning electron microscopy and atomic force microscopy measurements, which confirmed the structure of the self-molecular aggregates. Self-molecular aggregates were observed to be helical or sheet-like, and the gels were constructed by forming aggregates by self-molecular recognition.

Identifiants

pubmed: 37085981
doi: 10.1002/chem.202300455
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e202300455

Subventions

Organisme : The Mitani Foundation for Research and Development
Organisme : Shibuya Science Culture and Sports Foundation

Informations de copyright

© 2023 Wiley-VCH GmbH.

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Auteurs

Takahiro Soeta (T)

Division of Material Chemistry, Graduate School of Natural Science and Technology, Kanazawa University Kakuma, Kanazawa, Ishikawa, 920-1192, Japan.

Shota Kurobe (S)

Division of Material Chemistry, Graduate School of Natural Science and Technology, Kanazawa University Kakuma, Kanazawa, Ishikawa, 920-1192, Japan.

Yutaro Nirei (Y)

Division of Material Chemistry, Graduate School of Natural Science and Technology, Kanazawa University Kakuma, Kanazawa, Ishikawa, 920-1192, Japan.

Naoto Kurokawa (N)

Division of Material Chemistry, Graduate School of Natural Science and Technology, Kanazawa University Kakuma, Kanazawa, Ishikawa, 920-1192, Japan.

Weilin Wei (W)

Nano Life Science Institute (WPI-NanoLSI), Kanazawa University Kakuma, Kanazawa, Ishikawa, 920-1192, Japan.

Ayhan Yurtsever (A)

Nano Life Science Institute (WPI-NanoLSI), Kanazawa University Kakuma, Kanazawa, Ishikawa, 920-1192, Japan.

Takeshi Fukuma (T)

Nano Life Science Institute (WPI-NanoLSI), Kanazawa University Kakuma, Kanazawa, Ishikawa, 920-1192, Japan.

Yutaka Ukaji (Y)

Division of Material Chemistry, Graduate School of Natural Science and Technology, Kanazawa University Kakuma, Kanazawa, Ishikawa, 920-1192, Japan.

Classifications MeSH