Relevance of cortical arousals for risk stratification in sleep apnea: a 3 cohort analysis.

Male Middle Aged Humans Aged Cardiovascular Diseases / epidemiology Osteoporotic Fractures / complications Sleep Apnea Syndromes / complications Sleep Apnea, Obstructive / complications Arousal Cohort Studies Hypertension / complications Risk Assessment Diabetes Mellitus Atherosclerosis
arousal cardiovascular disease desaturation hypoxemia prediction sleep apnea

Journal

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
ISSN: 1550-9397
Titre abrégé: J Clin Sleep Med
Pays: United States
ID NLM: 101231977

Informations de publication

Date de publication:
01 08 2023
Historique:
pmc-release: 01 08 2024
medline: 5 10 2023
pubmed: 22 4 2023
entrez: 22 04 2023
Statut: ppublish

Résumé

There is uncertainty on best approaches for defining apnea-hypopnea events. To clarify the contributions of desaturation vs arousal to defining hypopneas, we examined the associations of events with desaturation (≥ 3%) but not arousal (apnea-hypopnea index [AHI] In the Sleep Heart Health Study (n = 5,473), the Multi-Ethnic Study of Atherosclerosis (n = 1,904), and the Osteoporotic Fractures in Men Study (n = 2,685), we examined the independent associations of AHI After adjusting for covariates and AHI based on events with electroencephalogram arousal (regardless of desaturation), AHI In middle-aged and older individuals, addition of events with arousals does not improve the strength of associations with comorbidities or incident cardiovascular disease. Research is needed to understand generalizability to younger individuals and the mechanistic role of arousals in obstructive sleep apnea. Azarbarzin A, Sands SA, Han S, et al. Relevance of cortical arousals for risk stratification in sleep apnea: a 3 cohort analysis.

Identifiants

DOI: 10.5664/jcsm.10598 PMID: 37086050 PMC: PMC10394366
pubmed: 37086050
pii: jcsm.10598
doi: 10.5664/jcsm.10598
pmc: PMC10394366
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

1475-1484

Subventions

Organisme : NHLBI NIH HHS
ID : R01 HL070839
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL070838
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL070837
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL070841
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL070842
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL070847
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL070848
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL071194
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR000128
Pays : United States
Organisme : NIAMS NIH HHS
ID : U01 AR066160
Pays : United States
Organisme : NIA NIH HHS
ID : U01 AG042168
Pays : United States
Organisme : NIA NIH HHS
ID : U01 AG042145
Pays : United States
Organisme : NIA NIH HHS
ID : U01 AG042143
Pays : United States
Organisme : NIA NIH HHS
ID : U01 AG042140
Pays : United States
Organisme : NIA NIH HHS
ID : U01 AG042139
Pays : United States
Organisme : NIA NIH HHS
ID : U01 AG042124
Pays : United States
Organisme : NIA NIH HHS
ID : U01 AG027810
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG070867
Pays : United States
Organisme : NHLBI NIH HHS
ID : P50 HL056984
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001420
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001079
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR000040
Pays : United States
Organisme : NHLBI NIH HHS
ID : N01HC95169
Pays : United States
Organisme : NHLBI NIH HHS
ID : N01HC95168
Pays : United States
Organisme : NHLBI NIH HHS
ID : N01HC95167
Pays : United States
Organisme : NHLBI NIH HHS
ID : N01HC95166
Pays : United States
Organisme : NHLBI NIH HHS
ID : N01HC95165
Pays : United States
Organisme : NHLBI NIH HHS
ID : N01HC95164
Pays : United States
Organisme : NHLBI NIH HHS
ID : N01HC95163
Pays : United States
Organisme : NHLBI NIH HHS
ID : N01HC95162
Pays : United States
Organisme : NHLBI NIH HHS
ID : N01HC95161
Pays : United States
Organisme : NHLBI NIH HHS
ID : N01HC95160
Pays : United States
Organisme : NHLBI NIH HHS
ID : N01HC95159
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201500003I
Pays : United States
Organisme : NHLBI NIH HHS
ID : U01 HL053931
Pays : United States
Organisme : NHLBI NIH HHS
ID : U01 HL063429
Pays : United States
Organisme : NHLBI NIH HHS
ID : U01 HL053934
Pays : United States
Organisme : NHLBI NIH HHS
ID : U01 HL053916
Pays : United States
Organisme : NHLBI NIH HHS
ID : U01 HL053938
Pays : United States
Organisme : NHLBI NIH HHS
ID : U01 HL053937
Pays : United States
Organisme : NHLBI NIH HHS
ID : U01 HL063463
Pays : United States
Organisme : NHLBI NIH HHS
ID : U01 HL053941
Pays : United States
Organisme : NHLBI NIH HHS
ID : R35 HL135818
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL153874
Pays : United States

Informations de copyright

© 2023 American Academy of Sleep Medicine.

Auteurs

Ali Azarbarzin (A)

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

Scott A Sands (SA)

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

Shaoling Han (S)

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

Tamar Sofer (T)

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

Gonzalo Labarca (G)

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

Katie L Stone (KL)

Research Institute, California Pacific Medical Center, San Francisco, California.

Daniel J Gottlieb (DJ)

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

Shahrokh Javaheri (S)

University of Cincinnati College of Medicine and the Bethesda North Hospital, Cincinnati, Ohio.

Andrew Wellman (A)

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

David P White (DP)

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

Susan Redline (S)

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Relevance of cortical arousals for risk...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Relevance of cortical arousals for risk...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Relevance of cortical arousals for risk...
questionsmedicales.fr › Maladies cardiovasculaires › Relevance of cortical arousals for risk...
questionsmedicales.fr › Plaies et blessures › Fractures osseuses › Fractures ostéoporotiques › Relevance of cortical arousals for risk...
questionsmedicales.fr › Maladies du système nerveux › Syndromes d'apnées du sommeil › Relevance of cortical arousals for risk...
questionsmedicales.fr › Maladies du système nerveux › Syndromes d'apnées du sommeil › Syndrome d'apnées obstructives du sommeil › Relevance of cortical arousals for risk...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Éveil › Relevance of cortical arousals for risk...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Relevance of cortical arousals for risk...
questionsmedicales.fr › Maladies cardiovasculaires › Maladies vasculaires › Hypertension artérielle › Relevance of cortical arousals for risk...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Appréciation des risques › Relevance of cortical arousals for risk...
questionsmedicales.fr › Maladies endocriniennes › Diabète › Relevance of cortical arousals for risk...
questionsmedicales.fr › Maladies cardiovasculaires › Maladies vasculaires › Artériopathies oblitérantes › Artériosclérose › Athérosclérose › Relevance of cortical arousals for risk...