Swarna Bhasma Induces Antigen-Presenting Abilities of Macrophages and Helps Antigen Experienced CD4

Immunomodulation Leishmania Macrophages Swarna Bhasma T cells

Journal

Biological trace element research
ISSN: 1559-0720
Titre abrégé: Biol Trace Elem Res
Pays: United States
ID NLM: 7911509

Informations de publication

Date de publication:
24 Apr 2023
Historique:
received: 12 02 2023
accepted: 03 04 2023
medline: 24 4 2023
pubmed: 24 4 2023
entrez: 23 04 2023
Statut: aheadofprint

Résumé

In leishmaniasis, the protective immunity is largely mediated by proinflammatory cytokine producing abilities of T cells and an efficient parasite killing by phagocytic cells. Notwithstanding a substantial progress that has been made during last decades, the mechanisms or factors involved in establishing protective immunity against Leishmania are not identified. In ancient Indian literature, metallic "bhasma," particularly that of "swarna" or gold (fine gold particles), is indicated as one of the most prominent metal-based therapeutic medicine, which is known to impart protective and curative properties in various health issues. In this work, we elucidated the potential of swarna bhasma (SB) on the effector properties of phagocytes and antigen-activated CD4

Identifiants

pubmed: 37088826
doi: 10.1007/s12011-023-03659-3
pii: 10.1007/s12011-023-03659-3
pmc: PMC10123016
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Institution of Eminence
ID : 6031

Informations de copyright

© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Références

J Exp Med. 1994 Feb 1;179(2):447-56
pubmed: 7905017
J Infect Dis. 2021 Feb 13;223(3):517-521
pubmed: 32614452
Nat Commun. 2021 Nov 4;12(1):6371
pubmed: 34737259
Chem Sci. 2017 Mar 1;8(3):1719-1735
pubmed: 28451297
Front Immunol. 2021 Mar 23;12:600659
pubmed: 33833751
PLoS Negl Trop Dis. 2017 Dec 14;11(12):e0006052
pubmed: 29240765
Cytokine. 2000 Aug;12(8):1228-31
pubmed: 10930301
Environ Sci Pollut Res Int. 2021 Oct;28(40):55925-55951
pubmed: 34491498
Molecules. 2017 May 22;22(5):
pubmed: 28531163
PLoS One. 2012;7(5):e35671
pubmed: 22693548
J Ayurveda Integr Med. 2021 Oct-Dec;12(4):640-648
pubmed: 34690042
J Immunol. 1988 Oct 1;141(7):2407-12
pubmed: 3139757
Vaccines (Basel). 2022 Mar 24;10(4):
pubmed: 35455254
Adv Drug Deliv Rev. 2008 Aug 17;60(11):1289-1306
pubmed: 18501989
Curr Med Chem. 2018;25(1):75-84
pubmed: 28359231
Pathogens. 2022 Mar 28;11(4):
pubmed: 35456085
Nat Immunol. 2002 Nov;3(11):1041-7
pubmed: 12407413
J Adv Pharm Technol Res. 2014 Jan;5(1):4-12
pubmed: 24696811
Phytomed Plus. 2022 Feb;2(1):100206
pubmed: 35403088
Front Cell Infect Microbiol. 2019 Mar 01;9:30
pubmed: 30881923
Nat Rev Immunol. 2003 Dec;3(12):984-93
pubmed: 14647480
Drug Discov Today Technol. 2020 Dec;38:57-67
pubmed: 34895641
J Trop Med. 2012;2012:819512
pubmed: 22131998
J Immunol Res. 2017;2017:7529408
pubmed: 29387733
Cells. 2021 Jan 07;10(1):
pubmed: 33430453
Expert Rev Vaccines. 2020 May;19(5):465-477
pubmed: 32306785
Parasite Immunol. 1985 Sep;7(5):545-55
pubmed: 3877902
J Immunol Methods. 1983 Dec 16;65(1-2):55-63
pubmed: 6606682
Parasit Vectors. 2016 Mar 01;9:118
pubmed: 26932389
Front Cell Infect Microbiol. 2012 Jun 12;2:83
pubmed: 22919674
Eur J Immunol. 1998 Feb;28(2):669-80
pubmed: 9521077
Front Immunol. 2019 Apr 05;10:670
pubmed: 31024534
Front Plant Sci. 2015 Aug 25;6:655
pubmed: 26379683
J Ayurveda Integr Med. 2010 Jan;1(1):77-80
pubmed: 21829307
Phytother Res. 2008 Jun;22(6):709-24
pubmed: 18446848
Drug Des Devel Ther. 2017 Dec 22;12:25-40
pubmed: 29317800
Front Immunol. 2012 Aug 14;3:251
pubmed: 22912637
Adv Appl Microbiol. 2013;82:155-84
pubmed: 23415155
Ann N Y Acad Sci. 2010 Dec;1213:46-61
pubmed: 20946578
Ayu. 2014 Oct-Dec;35(4):361-5
pubmed: 26195896
Drug News Perspect. 2002 Sep;15(7):417-431
pubmed: 12677177
Front Microbiol. 2018 May 07;9:883
pubmed: 29867798
Mem Inst Oswaldo Cruz. 2007 Aug;102(5):625-30
pubmed: 17710308
Int J Parasitol. 2003 Feb;33(2):153-62
pubmed: 12633653

Auteurs

Shashi Saini (S)

Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, 221 005, India.

Anshul Anand (A)

Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, 221 005, India.

Abhishek Singh (A)

Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, 221 005, India.

Baishakhi Mahapatra (B)

Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, 221 005, India.

Shruti Sirohi (S)

Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, 221 005, India.

Samer Singh (S)

Centre of Experimental Medicine and Surgery, Institute of Medical Science, Banaras Hindu University, Varanasi, 221 005, India.

Rakesh K Singh (RK)

Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, 221 005, India. rakesh_bc@bhu.ac.in.

Classifications MeSH