Incidence of asymptomatic SARS-CoV-2 infection in children undergoing elective otolaryngologic surgery throughout the COVID-19 pandemic.
asymptomatic COVID‐19
asymptomatic testing
asymptomatic transmission
pediatric COVID‐19
Journal
Laryngoscope investigative otolaryngology
ISSN: 2378-8038
Titre abrégé: Laryngoscope Investig Otolaryngol
Pays: United States
ID NLM: 101684963
Informations de publication
Date de publication:
Apr 2023
Apr 2023
Historique:
received:
10
02
2023
revised:
04
03
2023
accepted:
12
03
2023
medline:
24
4
2023
pubmed:
24
4
2023
entrez:
24
04
2023
Statut:
epublish
Résumé
Children infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are less clinically affected than adults, with most cases presenting as asymptomatic or mildly symptomatic. However, true rates of asymptomatic SARS-CoV-2 infection in children remain unclear. We sought to examine rates of SARS-CoV-2 in asymptomatic children and the role of children in transmission. We performed a retrospective review of patients between 6 months and 17 years of age who underwent elective or semi-elective otolaryngologic surgery with physicians affiliated with Weill Cornell Medicine between May 15, 2020 and March 31, 2022. Patients were included if they received molecular assay testing for SARS-CoV-2 without SARS-CoV-2 symptoms within 5 days of scheduled surgery. SARS-CoV-2 infection status, exposure, clinical symptoms, demographic data, and insurance status were recorded. 1047 patients met inclusion criteria. Thirteen positive cases (1.24%) were identified in the study population. Six cases occurred between December 2021 and February 2022 following the classification of the omicron variant as a variant of concern in November 2021. Five of the 13 cases occurred in children under 2 years of age. Seven patients were male, and five were female. Residences spanned all five boroughs of New York City and the surrounding metropolitan area. Throughout the pandemic, children have had a low rate of asymptomatic disease and likely pose a low risk of transmission of SARS-CoV-2 to the general population. Our results suggest that testing of asymptomatic children is a low-yield practice that is unlikely to influence rates of SARS-CoV-2 in the general population. 3.
Identifiants
pubmed: 37090872
doi: 10.1002/lio2.1046
pii: LIO21046
pmc: PMC10116989
doi:
Types de publication
Journal Article
Langues
eng
Pagination
599-603Informations de copyright
© 2023 The Authors. Laryngoscope Investigative Otolaryngology published by Wiley Periodicals LLC on behalf of The Triological Society.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
J Med Virol. 2021 Mar;93(3):1414-1420
pubmed: 32767703
Arthrosc Sports Med Rehabil. 2021 Aug;3(4):e1141-e1146
pubmed: 34002168
Pediatrics. 2020 Aug;146(2):
pubmed: 32457213
JAMA Surg. 2020 Aug 1;155(8):775-777
pubmed: 32496527
Front Pediatr. 2021 May 28;9:668484
pubmed: 34123972
J Pediatr. 2020 Dec;227:45-52.e5
pubmed: 32827525
Lancet Child Adolesc Health. 2020 May;4(5):397-404
pubmed: 32272089
Clin Infect Dis. 2020 Dec 3;71(9):2469-2479
pubmed: 32392337
Lancet Infect Dis. 2020 Aug;20(8):911-919
pubmed: 32353347
Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):17513-17515
pubmed: 32632012
Biomolecules. 2021 Jul 06;11(7):
pubmed: 34356617
JAMA Pediatr. 2021 Jan 1;175(1):16-18
pubmed: 32857158