Evaluation of the guideline-adherence of coronary angiography in patients with suspected chronic coronary syndrome - Results from the German prospective multicentre ENLIGHT-KHK project.

Angina pectoris Chronic coronary syndrome Coronary angiography Coronary artery disease Guideline adherence

Journal

International journal of cardiology. Heart & vasculature
ISSN: 2352-9067
Titre abrégé: Int J Cardiol Heart Vasc
Pays: Ireland
ID NLM: 101649525

Informations de publication

Date de publication:
Jun 2023
Historique:
received: 24 03 2023
accepted: 29 03 2023
medline: 24 4 2023
pubmed: 24 4 2023
entrez: 24 04 2023
Statut: epublish

Résumé

With 900'000 coronary angiographies (CA) per year, Germany has the highest annual per capita volume in Europe. Until now there are no prospective clinical data on the degree of guideline-adherence in the use of CA in patients with suspected chronic coronary syndrome (CCS) in Germany. Between January 2019 and August 2021, 458 patients with suspected CCS were recruited in nine German centres. Guideline-adherence was evaluated according to the current European Society of Cardiology and German guidelines. Pre-test probability (PTP) for CAD was determined using age, gender, and a standardized patient questionnaire to identify symptoms. Data on the diagnostic work-up were obtained from health records. Patients were in mean 66.6 years old, male in 57.3 %, had known CAD in 48.4 % and presented with typical, atypical, non-anginal chest pain or dyspnoea in 35.7 %, 41.3 %, 23.0 % and 25.4 %, respectively. PTP according to the European guidelines was in mean 24.2 % (11.9 %-36.5 % 95 % CI). 20.9 % of the patients received guideline-recommended preceding non-invasive image guided testing. The use of CA was adherent to the European and German guideline recommendations in 20.4 % and 25.4 %, respectively. In multivariate-analysis, arterial hypertension and prior revascularization were predictors of guideline non-adherence. These are the first prospective clinical data which demonstrated an overall low degree of guideline-adherence in the use of CA in patients with suspected CCS in the German health care setting. To improve adherence rates, the availability of and access to non-invasive image guided testing needs to be strengthened. (German Clinical Trials Registry DRKS00015638 - Registration Date: 19.02.2019).

Sections du résumé

Background UNASSIGNED
With 900'000 coronary angiographies (CA) per year, Germany has the highest annual per capita volume in Europe. Until now there are no prospective clinical data on the degree of guideline-adherence in the use of CA in patients with suspected chronic coronary syndrome (CCS) in Germany.
Methods UNASSIGNED
Between January 2019 and August 2021, 458 patients with suspected CCS were recruited in nine German centres. Guideline-adherence was evaluated according to the current European Society of Cardiology and German guidelines. Pre-test probability (PTP) for CAD was determined using age, gender, and a standardized patient questionnaire to identify symptoms. Data on the diagnostic work-up were obtained from health records.
Results UNASSIGNED
Patients were in mean 66.6 years old, male in 57.3 %, had known CAD in 48.4 % and presented with typical, atypical, non-anginal chest pain or dyspnoea in 35.7 %, 41.3 %, 23.0 % and 25.4 %, respectively. PTP according to the European guidelines was in mean 24.2 % (11.9 %-36.5 % 95 % CI). 20.9 % of the patients received guideline-recommended preceding non-invasive image guided testing. The use of CA was adherent to the European and German guideline recommendations in 20.4 % and 25.4 %, respectively. In multivariate-analysis, arterial hypertension and prior revascularization were predictors of guideline non-adherence.
Conclusion UNASSIGNED
These are the first prospective clinical data which demonstrated an overall low degree of guideline-adherence in the use of CA in patients with suspected CCS in the German health care setting. To improve adherence rates, the availability of and access to non-invasive image guided testing needs to be strengthened. (German Clinical Trials Registry DRKS00015638 - Registration Date: 19.02.2019).

Identifiants

pubmed: 37091914
doi: 10.1016/j.ijcha.2023.101203
pii: S2352-9067(23)00034-9
pmc: PMC10120367
doi:

Types de publication

Journal Article

Langues

eng

Pagination

101203

Informations de copyright

© 2023 The Author(s).

Déclaration de conflit d'intérêts

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Références

BMJ Open. 2018 Nov 25;8(11):e020388
pubmed: 30478102
JAMA Intern Med. 2014 Oct;174(10):1630-9
pubmed: 25156821
Circ Cardiovasc Interv. 2019 Jul;12(7):e007791
pubmed: 31284736
Z Evid Fortbild Qual Gesundhwes. 2017 Nov;127-128:62-71
pubmed: 28711420
Eur J Prev Cardiol. 2013 Oct;20(5):872-9
pubmed: 22508692
Dtsch Arztebl Int. 2020 Feb 28;117(9):137-144
pubmed: 32234189
BMC Cardiovasc Disord. 2022 Feb 26;22(1):72
pubmed: 35219312
Eur Heart J. 2020 Jan 14;41(3):407-477
pubmed: 31504439
Eur Heart J. 2013 Oct;34(38):2949-3003
pubmed: 23996286
Wien Klin Wochenschr. 2013 Dec;125(23-24):736-49
pubmed: 24356726
N Engl J Med. 2022 Apr 28;386(17):1591-1602
pubmed: 35240010
Int J Equity Health. 2018 Nov 1;17(1):160
pubmed: 30382861
PLoS One. 2015 Feb 26;10(2):e0117172
pubmed: 25719869
Cardiovasc Revasc Med. 2021 Oct;31:19-25
pubmed: 33288463

Auteurs

Bastian Wein (B)

Elisabeth-Hospital, Contilia Heart and Vascular Centre, Essen, Germany.
Cardiology, Faculty of Medicine, University of Augsburg, Germany.

Yana Seleznova (Y)

Institute for Health Economics and Clinical Epidemiology, University of Cologne, Germany.

Dirk Mueller (D)

Institute for Health Economics and Clinical Epidemiology, University of Cologne, Germany.

Marie Naumann (M)

Institute for Health Economics and Clinical Epidemiology, University of Cologne, Germany.

Simon Loeser (S)

AOK Rheinland-Hamburg, Dusseldorf, Germany.

Joerg Artmann (J)

Institute for Health Economics and Clinical Epidemiology, University of Cologne, Germany.

Thomas Fritz (T)

AOK NORDWEST, Dortmund, Germany.

Melanie Steffen (M)

Elisabeth-Hospital, Contilia Heart and Vascular Centre, Essen, Germany.

Ute Windhoevel (U)

CERC Deutschland GmbH, Essen, Germany.

Michael Haude (M)

Rheinlandklinikum Neuss, Germany.

Juergen Vom Dahl (J)

Mariahilf Hospital, Moenchengladbach, Germany.

Ulrich Schaefer (U)

Heart and Vascular Centre, Bad Bevensen, Germany.

Moritz Montenbruck (M)

Marien-Hospital, Hamburg, Germany.

Markus Zarse (M)

Medical Department III, Maerkische Kliniken, Luedenscheid, Germany.

Ruediger Jegodka (R)

Elisabeth Hospital, Recklinghausen, Germany.

Thorsten Dill (T)

Sana Hospital Benrath, Medical Department, Dusseldorf, Germany.

Jan-Erik Guelker (JE)

Petrus Hospital, Department of Cardiology and Rhythmology, Wuppertal, Germany.
University Witten/Herdecke, Faculty of Health, Witten, Germany.

Dirk Boese (D)

Hochsauerland Hospital, Department of Cardiology, Arnsberg, Germany.

Oliver Bruder (O)

Elisabeth-Hospital, Contilia Heart and Vascular Centre, Essen, Germany.
Ruhr University Bochum, Germany.

Classifications MeSH