The Expressions of NF-κB, COX-2, Sp1, and c-Jun in Pancreatic Ductal Adenocarcinoma and Their Associations with Patient Survival.

Sp1 cyclooxygenase−2 c−Jun nuclear factor kappa−B pancreatic neoplasms

Journal

Pathophysiology : the official journal of the International Society for Pathophysiology
ISSN: 1873-149X
Titre abrégé: Pathophysiology
Pays: Switzerland
ID NLM: 9433813

Informations de publication

Date de publication:
25 Mar 2023
Historique:
received: 15 12 2022
revised: 22 03 2023
accepted: 23 03 2023
medline: 24 4 2023
pubmed: 24 4 2023
entrez: 24 04 2023
Statut: epublish

Résumé

Chronic inflammation is a crucial driver of carcinogenesis in pancreatic ductal adenocarcinoma (PDAC). Several studies have investigated the prognostic significance of cyclooxygenase-2 (COX-2) expression in PDAC patients, obtaining conflicting results. Nuclear factor kappa-B (NF-κB), specificity protein 1 (Sp1), and c-Jun are known as the transcription factors of the

Identifiants

pubmed: 37092523
pii: pathophysiology30020009
doi: 10.3390/pathophysiology30020009
pmc: PMC10123625
doi:

Types de publication

Journal Article

Langues

eng

Pagination

92-109

Subventions

Organisme : University of Indonesia
ID : NKB-1589/UN2.RST/HKP.05.00/2020

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Auteurs

Kaka Renaldi (K)

Doctoral Program in Medical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta 10430, Indonesia.
Division of Gastroenterology, Pancreatobiliary and Gastrointestinal Endoscopy, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia.
Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia.

Marcellus Simadibrata (M)

Division of Gastroenterology, Pancreatobiliary and Gastrointestinal Endoscopy, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia.
Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia.

Nur Rahadiani (N)

Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia.

Diah Rini Handjari (DR)

Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia.

Alida Roswita Harahap (AR)

Doctoral Program in Medical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta 10430, Indonesia.

Kuntjoro Harimurti (K)

Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia.

Nasrul Zubir (N)

Division of Gastroenterology, Department of Internal Medicine, Dr. M. Djamil Hospital, Padang 25171, Indonesia.

Lianda Siregar (L)

Division of Gastroenterohepatology, Dharmais National Cancer Hospital, Jakarta 11420, Indonesia.

Imelda Maria Loho (IM)

Division of Gastroenterohepatology, Dharmais National Cancer Hospital, Jakarta 11420, Indonesia.

Evlina Suzanna (E)

Department of Anatomical Pathology, Dharmais National Cancer Hospital, Jakarta 11420, Indonesia.

Bonita Prawirodihardjo (B)

Department of Anatomical Pathology, Fatmawati Central General Hospital, Jakarta 12430, Indonesia.

Heriawaty Hidajat (H)

Department of Anatomical Pathology, Persahabatan Central General Hospital, Jakarta 13230, Indonesia.

Budi Widodo (B)

Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo General Academic Hospital, Surabaya 60286, Indonesia.

Alphania Rahniayu (A)

Department of Anatomical Pathology, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo General Academic Hospital, Surabaya 60286, Indonesia.

Renaningtyas Tambun (R)

Department of Anatomical Pathology, St. Carolus Hospital, Jakarta 10440, Indonesia.

Andy William (A)

Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia.

Dadang Makmun (D)

Division of Gastroenterology, Pancreatobiliary and Gastrointestinal Endoscopy, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia.
Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta 10430, Indonesia.

Classifications MeSH