Estimated preventable COVID-19-associated deaths due to non-vaccination in the United States.


Journal

European journal of epidemiology
ISSN: 1573-7284
Titre abrégé: Eur J Epidemiol
Pays: Netherlands
ID NLM: 8508062

Informations de publication

Date de publication:
Nov 2023
Historique:
received: 17 11 2022
accepted: 07 04 2023
medline: 23 11 2023
pubmed: 24 4 2023
entrez: 24 04 2023
Statut: ppublish

Résumé

While some studies have previously estimated lives saved by COVID-19 vaccination, we estimate how many deaths could have been averted by vaccination in the US but were not because of a failure to vaccinate. We used a simple method based on a nationally representative dataset to estimate the preventable deaths among unvaccinated individuals in the US from May 30, 2021 to September 3, 2022 adjusted for the effects of age and time. We estimated that at least 232,000 deaths could have been prevented among unvaccinated adults during the 15 months had they been vaccinated with at least a primary series. While uncertainties exist regarding the exact number of preventable deaths and more granular data are needed on other factors causing differences in death rates between the vaccinated and unvaccinated groups to inform these estimates, this method is a rapid assessment on vaccine-preventable deaths due to SARS-CoV-2 that has crucial public health implications. The same rapid method can be used for future public health emergencies.

Identifiants

pubmed: 37093505
doi: 10.1007/s10654-023-01006-3
pii: 10.1007/s10654-023-01006-3
pmc: PMC10123459
doi:

Substances chimiques

COVID-19 Vaccines 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1125-1128

Subventions

Organisme : NCI NIH HHS
ID : U01 CA261277
Pays : United States

Informations de copyright

© 2023. The Author(s).

Références

Schneider EC, Shah A, Sah P, Vilches T, Pandey A, Moghadas SM, et al. Impact of U.S. COVID-19 vaccination efforts: an update on averted deaths, hospitalizations, and health care costs through March 2022. 2022. Available at: https://www.commonwealthfund.org/blog/2022/impact-us-covid-19-vaccination-efforts-march-update . Accessed 16 August 2022.
Vilches TN, Moghadas SM, Sah P, Fitzpatrick MC, Shoukat A, Pandey A, et al. Estimating COVID-19 infections, hospitalizations, and deaths following the US vaccination campaigns during the pandemic. JAMA Netw Open. 2022;5(1):e2142725-e. https://doi.org/10.1001/jamanetworkopen.2021.42725 .
doi: 10.1001/jamanetworkopen.2021.42725
Shoukat A, Vilches TN, Moghadas SM, Sah P, Schneider EC, Shaff J, et al. Lives saved and hospitalizations averted by COVID-19 vaccination in New York City: a modeling study. Lancet Reg Health Am. 2022;5:100085. https://doi.org/10.1016/j.lana.2021.100085 .
doi: 10.1016/j.lana.2021.100085 pubmed: 34746912
Centers for Disease Control and Prevention. Rates of COVID-19 cases or deaths by age group and vaccination status. Available at: https://data.cdc.gov/Public-Health-Surveillance/Rates-of-COVID-19-Cases-or-Deaths-by-Age-Group-and/3rge-nu2a . Accessed 24 Mar 2023.
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Zhong M, Glazer T, Kshirsagar M, Johnston R, Dodhia R, Kim A, et al. Estimating vaccine-preventable COVID-19 deaths under counterfactual vaccination scenarios in the United States. 2022. Available at: https://www.researchsquare.com/article/rs-2618112/latest.pdf . Accessed 24 Mar 2023.
Council of State and Territorial Epidemiologists (CSTE). Interim guidance for public health surveillance programs for classification of COVID-19-associated deaths among COVID-19 cases. Available at: https://cdn.ymaws.com/www.cste.org/resource/resmgr/pdfs/pdfs2/20211222_interim-guidance.pdf . Accessed 22 Mar 2023.
Bonvini M, Kennedy EH, Ventura V, Wasserman L. Causal inference for the effect of mobility on COVID-19 deaths. Ann Appl Stat. 2021;16(4):2458–80. https://doi.org/10.1214/22-AOAS1599 .
doi: 10.1214/22-AOAS1599

Auteurs

Katherine M Jia (KM)

Center for Communicable Disease Dynamics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. kjia@g.harvard.edu.

William P Hanage (WP)

Center for Communicable Disease Dynamics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Marc Lipsitch (M)

Center for Communicable Disease Dynamics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Amelia G Johnson (AG)

COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Avnika B Amin (AB)

COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA, USA.

Akilah R Ali (AR)

COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Heather M Scobie (HM)

COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, GA, USA.

David L Swerdlow (DL)

Center for Communicable Disease Dynamics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

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