Coinfection of COVID-19 and Tuberculosis in Uganda.


Journal

The American journal of tropical medicine and hygiene
ISSN: 1476-1645
Titre abrégé: Am J Trop Med Hyg
Pays: United States
ID NLM: 0370507

Informations de publication

Date de publication:
07 06 2023
Historique:
received: 29 11 2022
accepted: 18 02 2023
medline: 9 6 2023
pubmed: 25 4 2023
entrez: 24 04 2023
Statut: epublish

Résumé

The clinical features and outcomes of tuberculosis (TB) and COVID-19 coinfection are not well established. This short report describes 11 people with TB/COVID-19 coinfection in Uganda. The mean age was 46.9 ± 14.5 years; eight (72.7%) were male and two (18.2%) were coinfected with HIV. All patients presented with cough whose median duration was 71.1 (interquartile range, 33.1, 109) days. Eight (72.7%) had mild COVID-19 whereas two (18.2%) died, including one with advanced HIV disease. All patients were treated with first-line anti-TB drugs and adjunct therapy for COVID-19 using national treatment guidelines. This report presents the possibility of the coexistence of the two diseases and calls for more vigilance, screening, and collective prevention measures for both COVID-19 and TB.

Identifiants

pubmed: 37094784
doi: 10.4269/ajtmh.22-0738
pii: ajtmh.22-0738
pmc: PMC10540107
doi:

Substances chimiques

Antitubercular Agents 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

1240-1243

Subventions

Organisme : FIC NIH HHS
ID : D43 TW011632
Pays : United States

Commentaires et corrections

Type : CommentIn

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Auteurs

Edwin Nuwagira (E)

Department of Internal Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
Tuberculosis Treatment Unit, Mbarara Regional Referral Hospital, Mbarara, Uganda.

Stellah G Mpagama (SG)

Infectious Diseases Unit, Kibong'oto Infectious Disease Hospital, Kilimanjaro, Tanzania.

Asumpta Katusiime (A)

Tuberculosis Treatment Unit, Mbarara Regional Referral Hospital, Mbarara, Uganda.

Bobson Natamba (B)

Tuberculosis Treatment Unit, Mbarara Regional Referral Hospital, Mbarara, Uganda.

Joseph Baruch Baluku (JB)

Division of Pulmonology, Kiruddu National Referral Hospital, Kampala, Uganda.

Peggy S Lai (PS)

Division of Pulmonology, Massachusetts General Hospital, Boston, Massachusetts.

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Classifications MeSH