Dramatic elevation of LDL cholesterol from ketogenic-dieting: A Case Series.

Genetic Hypercholesterolemia Hyperlipidemia Ketogenic diet

Journal

American journal of preventive cardiology
ISSN: 2666-6677
Titre abrégé: Am J Prev Cardiol
Pays: Netherlands
ID NLM: 101769122

Informations de publication

Date de publication:
Jun 2023
Historique:
received: 21 02 2023
revised: 24 03 2023
accepted: 01 04 2023
medline: 25 4 2023
pubmed: 25 4 2023
entrez: 25 04 2023
Statut: epublish

Résumé

High-fat, low carb dieting, also known as the "ketogenic diet," has increased in popularity as a rapid weight-loss tool. Previous studies describe a modest elevation in cholesterol in the average keto-diet participant without specific cardiovascular impact. We hypothesize that patients with a genetic predisposition to cholesterol metabolism dysregulation may have a disproportionate elevation in cholesterol in response to ketogenic dieting.

Identifiants

pubmed: 37096158
doi: 10.1016/j.ajpc.2023.100495
pii: S2666-6677(23)00036-3
pmc: PMC10121782
doi:

Types de publication

Journal Article

Langues

eng

Pagination

100495

Informations de copyright

©2023PublishedbyElsevierB.V.

Déclaration de conflit d'intérêts

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Références

Br J Nutr. 2013 Oct;110(7):1178-87
pubmed: 23651522
Atherosclerosis. 2020 Jan;292:119-126
pubmed: 31805451
Circulation. 2019 Apr 9;139(15):1828-1845
pubmed: 30958719
Trends Mol Med. 2020 Dec;26(12):1086-1100
pubmed: 32861590
Eur J Paediatr Neurol. 2014 Jul;18(4):489-94
pubmed: 24703903
Consult Pharm. 2017 Jul 1;32(7):388-396
pubmed: 28701250
JAMA. 2018 Jan 16;319(3):215-217
pubmed: 29340675
Circulation. 2019 Sep 10;140(11):e596-e646
pubmed: 30879355
J Clin Lipidol. 2021 Jan-Feb;15(1):61-67
pubmed: 33191194
J Clin Lipidol. 2019 Sep - Oct;13(5):689-711.e1
pubmed: 31611148
BMJ Open Sport Exerc Med. 2018 Oct 04;4(1):e000429
pubmed: 30305928
Nutr Res. 2019 Feb;62:64-77
pubmed: 30803508
Curr Dev Nutr. 2021 Nov 30;6(1):nzab144
pubmed: 35106434

Auteurs

Tyler Schmidt (T)

Department of Cardiovascular Disease, Mayo Clinic, Rochester, MN, United States.

David M Harmon (DM)

Department of Cardiovascular Disease, Mayo Clinic, Rochester, MN, United States.

Erica Kludtke (E)

Department of Cardiovascular Disease, Mayo Clinic, Rochester, MN, United States.

Alicia Mickow (A)

Department of Cardiovascular Disease, Mayo Clinic, Rochester, MN, United States.

Vinaya Simha (V)

Division of Endocrinology, Diabetes, and Metabolism, Mayo Clinic, Rochester, MN, United States.

Stephen Kopecky (S)

Department of Cardiovascular Disease, Mayo Clinic, Rochester, MN, United States.

Classifications MeSH