Myopia Control Dose Delivered to Treated Eyes by a Dual-focus Myopia-control Contact Lens.
Journal
Optometry and vision science : official publication of the American Academy of Optometry
ISSN: 1538-9235
Titre abrégé: Optom Vis Sci
Pays: United States
ID NLM: 8904931
Informations de publication
Date de publication:
01 06 2023
01 06 2023
Historique:
medline:
29
6
2023
pubmed:
25
4
2023
entrez:
25
4
2023
Statut:
ppublish
Résumé
This study examined the optical impact of a DF contact lens during near viewing in a sample of habitual DF lens wearing children. Seventeen myopic children aged 14 to 18 years who had completed 3 or 6 years of treatment with a DF contact lens (MiSight 1 Day; CooperVision, Inc., San Ramon, CA) were recruited and fit bilaterally with the DF and a single-vision (Proclear 1 Day; CooperVision, Inc.) contact lens. Right eye wavefronts were measured using a pyramidal aberrometer (Osiris; CSO, Florence, Italy) while children accommodated binocularly to high-contrast letter stimuli at five target vergences. Wavefront error data were used to compute pupil maps of refractive state. During near viewing, children wearing single-vision lenses accommodated on average to achieve approximate focus in the pupil center but, because of combined accommodative lag and negative spherical aberration, experienced up to 2.00 D of hyperopic defocus in the pupil margins. With DF lenses, children accommodated similarly achieving approximate focus in the pupil center. When viewing three near distances (0.48, 0.31, and 0.23 m), the added +2.00 D within the DF lens treatment optics shifted the mean defocus from +0.75 to -1.00 D. The DF lens reduced the percentage of hyperopic defocus (≥+0.75 D) in the retinal image from 52 to 25% over these target distances, leading to an increase in myopic defocus (≤-0.50 D) from 17 to 42%. The DF contact lens did not alter the accommodative behavior of children. The treatment optics introduced myopic defocus and decreased the amount of hyperopically defocused light in the retinal image.
Identifiants
pubmed: 37097975
doi: 10.1097/OPX.0000000000002021
pii: 00006324-202306000-00003
pmc: PMC10317304
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
376-387Informations de copyright
Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Optometry.
Déclaration de conflit d'intérêts
Conflict of Interest Disclosure: NSL and PSK received financial support from CooperVision. MR is a consultant to CooperVision. PC, BA, and AB are employees of CooperVision. The sponsor participated in study design, analysis, and interpretation. All authors were responsible for the preparation of this article and the decision to submit this article for publication. The investigators at Aston University (NSL, SJ) had full access to the study data; the Indiana University investigators (VR, DM, MJ, MR, PSK) had partial access to the study data and take full responsibility for their presentation in this article. The lead author affirms that the article is an honest, accurate, and transparent account of the study being reported and that no important aspects of the study have been omitted. All investigators take responsibility for the integrity of the data and have critically reviewed the article for important intellectual content.
Références
Holden BA, Fricke TR, Wilson DA, et al. Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050. Ophthalmology 2016;123:1036–42.
Ding BY, Shih YF, Lin LL, et al. Myopia among Schoolchildren in East Asia and Singapore. Surv Ophthalmol 2017;62:677–97.
Jung SK, Lee JH, Kakizaki H, et al. Prevalence of Myopia and Its Association with Body Stature and Educational Level in 19-year-old Male Conscripts in Seoul, South Korea. Invest Ophthalmol Vis Sci 2012;53:5579–83.
Wildsoet CF, Chia A, Cho P, et al. IMI — Interventions Myopia Institute: Interventions for Controlling Myopia Onset and Progression Report. Invest Ophthalmol Vis Sci 2019;60:M106–31.
Fricke TR, Jong M, Naidoo KS, et al. Global Prevalence of Visual Impairment Associated with Myopic Macular Degeneration and Temporal Trends from 2000 through 2050: Systematic Review, Meta-analysis and Modelling. Br J Ophthalmol 2018;102:855–62.
Klaver CC, Wolfs RC, Vingerling JR, et al. Age-specific Prevalence and Causes of Blindness and Visual Impairment in an Older Population: The Rotterdam Study. Arch Ophthalmol 1998;116:653–8.
Tang Y, Wang X, Wang J, et al. Prevalence and Causes of Visual Impairment in a Chinese Adult Population: The Taizhou Eye Study. Ophthalmology 2015;122:1480–8.
Xiao O, Guo X, Wang D, et al. Distribution and Severity of Myopic Maculopathy among Highly Myopic Eyes. Invest Ophthalmol Vis Sci 2018;59:4880–5.
Walline JJ, Walker MK, Mutti DO, et al. Effect of High Add Power, Medium Add Power, or Single-vision Contact Lenses on Myopia Progression in Children: The Blink Randomized Clinical Trial. JAMA 2020;324:571–80.
Lam CS, Tang WC, Qi H, et al. Effect of Defocus Incorporated Multiple Segments Spectacle Lens Wear on Visual Function in Myopic Chinese Children. Transl Vis Sci Technol 2020;9:11.
Chamberlain P, Peixoto-de-Matos SC, Logan NS, et al. A 3-year Randomized Clinical Trial of MiSight Lenses for Myopia Control. Optom Vis Sci 2019;96:556–67.
Smith EL 3rd. Optical Treatment Strategies to Slow Myopia Progression: Effects of the Visual Extent of the Optical Treatment Zone. Exp Eye Res 2013;114:77–88.
Jaskulski M, Singh NK, Bradley A, et al. Optical and Imaging Properties of a Novel Multi-segment Spectacle Lens Designed to Slow Myopia Progression. Ophthalmic Physiol Opt 2020;40:549–56.
Bao J, Yang A, Huang Y, et al. One-year Myopia Control Efficacy of Spectacle Lenses with Aspherical Lenslets. Br J Ophthalmol 2022;106:1171–6.
Rappon J, Chung C, Young G, et al. Control of Myopia Using Diffusion Optics Spectacle Lenses: 12-Month Results of a Randomised Controlled, Efficacy and Safety Study (CYPRESS). Br J Ophthalmol 2022;bjophthalmol–2021–321005.
Cheng X, Xu J, Chehab K, et al. Soft Contact Lenses with Positive Spherical Aberration for Myopia Control. Optom Vis Sci 2016;93:353–66.
Berntsen DA, Sinnott LT, Mutti DO, et al. A Randomized Trial Using Progressive Addition Lenses to Evaluate Theories of Myopia Progression in Children with a High Lag of Accommodation. Invest Ophthalmol Vis Sci 2012;53:640–9.
U.S. Food and Drug Administration (FDA). MiSight 1 Day (omafilcon A) Soft (Hydrophilic) Contact Lenses for Daily Wear. Available at: https://www.accessdata.fda.gov/Scripts/Cdrh/Cfdocs/Cfpma/Pma.Cfm?Id=P180035 . Accessed September 19, 2022.
Arumugam B, Hung LF, To CH, et al. The Effects of Simultaneous Dual Focus Lenses on Refractive Development in Infant Monkeys. Invest Ophthalmol Vis Sci 2014;55:7423–32.
Arumugam B, Hung LF, To CH, et al. The Effects of the Relative Strength of Simultaneous Competing Defocus Signals on Emmetropization in Infant Rhesus Monkeys. Invest Ophthalmol Vis Sci 2016;57:3949–60.
Singh NK, Meyer D, Jaskulski M, et al. Retinal Defocus in Myopes Wearing Dual-focus Zonal Contact Lenses. Ophthalmic Physiol Opt 2022;42:8–18.
Cheng X, Xu J, Brennan NA. Accommodation and Its Role in Myopia Progression and Control with Soft Contact Lenses. Ophthalmic Physiol Opt 2019;39:162–71.
Mutti DO, Mitchell GL, Hayes JR, et al. Accommodative Lag before and after the Onset of Myopia. Invest Ophthalmol Vis Sci 2006;47:837–46.
Nakatsuka C, Hasebe S, Nonaka F, et al. Accommodative Lag under Habitual Seeing Conditions: Comparison between Myopic and Emmetropic Children. Jpn J Ophthalmol 2005;49:189–94.
Tarrant J, Severson H, Wildsoet CF. Accommodation in Emmetropic and Myopic Young Adults Wearing Bifocal Soft Contact Lenses. Ophthalmic Physiol Opt 2008;28:62–72.
Cheng H, Barnett JK, Vilupuru AS, et al. A Population Study on Changes in Wave Aberrations with Accommodation. J Vis 2004;4:272–80.
Lopez-Gil N, Fernandez-Sanchez V. The Change of Spherical Aberration during Accommodation and Its Effect on the Accommodation Response. J Vis 2010;10:12.
Plainis S, Ginis HS, Pallikaris A. The Effect of Ocular Aberrations on Steady-state Errors of Accommodative Response. J Vis 2005;5:466–77.
Thibos LN, Bradley A, Lopez-Gil N. Modelling the Impact of Spherical Aberration on Accommodation. Ophthalmic Physiol Opt 2013;33:482–96.
Altoaimi BH, Almutairi MS, Kollbaum PS, et al. Accommodative Behavior of Young Eyes Wearing Multifocal Contact Lenses. Optom Vis Sci 2018;95:416–27.
Howlett MH, McFadden SA. Spectacle Lens Compensation in the Pigmented Guinea Pig. Vision Res 2009;49:219–27.
Troilo D, Totonelly K, Harb E. Imposed Anisometropia, Accommodation, and Regulation of Refractive State. Optom Vis Sci 2009;86:E31–9.
Smith EL 3rd, Hung LF. The Role of Optical Defocus in Regulating Refractive Development in Infant Monkeys. Vision Res 1999;39:1415–35.
Winawer J, Wallman J. Temporal Constraints on Lens Compensation in Chicks. Vision Res 2002;42:2651–68.
Tse DY, Lam CS, Guggenheim JA, et al. Simultaneous Defocus Integration during Refractive Development. Invest Ophthalmol Vis Sci 2007;48:5352–9.
McFadden SA, Tse DY, Bowrey HE, et al. Integration of Defocus by Dual Power Fresnel Lenses Inhibits Myopia in the Mammalian Eye. Invest Ophthalmol Vis Sci 2014;55:908–17.
Gifford KL, Schmid KL, Collins JM, et al. Multifocal Contact Lens Design, Not Addition Power, Affects Accommodation Responses in Young Adult Myopes. Ophthalmic Physiol Opt 2021;41:1346–54.
Altoaimi BH, Kollbaum P, Meyer D, et al. Experimental Investigation of Accommodation in Eyes Fit with Multifocal Contact Lenses Using a Clinical Auto-refractor. Ophthalmic Physiol Opt 2018;38:152–63.
Hammond D, Chamberlain P, Arumugam B, et al. Eye Growth of Children Undergoing Myopia Control Treatment Compared with Emmetropic Eye Growth. Ophthalmologe 2022;119:147–8.
Chamberlain P, Bradley A, Arumugam B, et al. Long-term Effect of Dual-focus Contact Lenses on Myopia Progression in Children: A 6-year Multicenter Clinical Trial. Optom Vis Sci 2022;99:204–12.
Kollbaum PS, Bradley A, Thibos LN. Comparing the Optical Properties of Soft Contact Lenses On and Off the Eye. Optom Vis Sci 2013;90:924–36.
Kollbaum PS, Jansen ME, Tan J, et al. Vision Performance with a Contact Lens Designed to Slow Myopia Progression. Optom Vis Sci 2013;90:205–14.
Kollbaum P, Jansen M, Thibos L, et al. Validation of an Off-eye Contact Lens Shack-Hartmann Wavefront Aberrometer. Optom Vis Sci 2008;85:E817–28.
Singh NK, Jaskulski M, Ramasubramanian V, et al. Validation of a Clinical Aberrometer Using Pyramidal Wavefront Sensing. Optom Vis Sci 2019;96:733–44.
Applegate RA, Lakshminarayanan V. Parametric Representation of Stiles-Crawford Functions: Normal Variation of Peak Location and Directionality. J Opt Soc Am (A) 1993;10:1611–23.
Flitcroft DI, He M, Jonas JB, et al. IMI—Defining and Classifying Myopia: A Proposed Set of Standards for Clinical and Epidemiologic Studies. Invest Ophthalmol Vis Sci 2019;60:M20–30.
Leat SJ. To Prescribe or Not to Prescribe? Guidelines for Spectacle Prescribing in Infants and Children. Clin Exp Optom 2011;94:514–27.
Howarth RJ. Sources for a History of the Ternary Diagram. Br J Hist Sci 1996;29:337–56.
Bradley A, Nam J, Xu R, et al. Impact of Contact Lens Zone Geometry and Ocular Optics on Bifocal Retinal Image Quality. Ophthalmic Physiol Opt 2014;34:331–45.
Ruiz-Pomeda A, Perez-Sanchez B, Canadas P, et al. Binocular and Accommodative Function in the Controlled Randomized Clinical Trial MiSight® Assessment Study Spain (MASS). Graefes Arch Clin Exp Ophthalmol 2019;257:207–15.
Thibos LN, Bradley A, Liu T, et al. Spherical Aberration and the Sign of Defocus. Optom Vis Sci 2013;90:1284–91.
Rose KA, Morgan IG, Ip J, et al. Outdoor Activity Reduces the Prevalence of Myopia in Children. Ophthalmology 2008;115:1279–85.
Wu PC, Tsai CL, Hu CH, et al. Effects of Outdoor Activities on Myopia among Rural School Children in Taiwan. Ophthalmic Epidemiol 2010;17:338–42.
Wu PC, Tsai CL, Wu HL, et al. Outdoor Activity during Class Recess Reduces Myopia Onset and Progression in School Children. Ophthalmology 2013;120:1080–5.
Ravikumar S, Bradley A, Thibos LN. Chromatic Aberration and Polychromatic Image Quality with Diffractive Multifocal Intraocular Lenses. J Cataract Refract Surg 2014;40:1192–204.
Wallman J, Winawer J. Homeostasis of Eye Growth and the Question of Myopia. Neuron 2004;43:447–68.
Smith EL 3rd, Hung LF, Huang J. Relative Peripheral Hyperopic Defocus Alters Central Refractive Development in Infant Monkeys. Vision Res 2009;49:2386–92.
Flitcroft DI. The Complex Interactions of Retinal, Optical and Environmental Factors in Myopia Aetiology. Prog Retin Eye Res 2012;31:622–60.