A druggable copper-signalling pathway that drives inflammation.

Animals Mice Copper / metabolism Inflammation / drug therapy Macrophages / drug effects NAD / metabolism Signal Transduction / drug effects Mitochondria / drug effects Hydrogen Peroxide / metabolism Epigenesis, Genetic / drug effects Metformin / analogs & derivatives Oxidation-Reduction Cell Plasticity / drug effects Macrophage Activation / drug effects

Journal

Nature

ISSN: 1476-4687

Titre abrégé: Nature

Pays: England

ID NLM: 0410462

Informations de publication

Date de publication:
May 2023

Historique:

received: 21 03 2022

accepted: 27 03 2023

medline: 12 5 2023

pubmed: 27 4 2023

entrez: 26 4 2023

Statut: ppublish

Résumé

Inflammation is a complex physiological process triggered in response to harmful stimuli

Identifiants

DOI: 10.1038/s41586-023-06017-4 PMID: 37100912 PMC: PMC10131557

pubmed: 37100912

doi: 10.1038/s41586-023-06017-4

pii: 10.1038/s41586-023-06017-4

pmc: PMC10131557

doi:

Substances chimiques

Copper 789U1901C5

NAD 0U46U6E8UK

Cd44 protein, mouse 0

Hydrogen Peroxide BBX060AN9V

Metformin 9100L32L2N

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

Pagination

386-394

Commentaires et corrections

Type : CommentIn

Informations de copyright

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