Evaluation of the susceptibility of Tritrichomonas foetus to extracts of Lantana camara (Verbenaceae) by flow cytometry.
Bovine trichomoniasis
Flow cytometry
Lantana camara
Natural therapeutic agents
Tritrichomonas foetus
Journal
Veterinary research communications
ISSN: 1573-7446
Titre abrégé: Vet Res Commun
Pays: Switzerland
ID NLM: 8100520
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
received:
26
01
2023
accepted:
13
04
2023
medline:
8
9
2023
pubmed:
27
4
2023
entrez:
26
4
2023
Statut:
ppublish
Résumé
Bovine Trichomonosis (BT), a sexually transmitted disease endemic in countries with extensive cattle farming and natural service, is one of the most common causes of reproductive failure. 5-nitroimidazoles and their derivatives are used for its treatment, mainly metronidazole. The emergence of drug resistance mechanisms and treatment failures raise the need to investigate the effectiveness of new active compounds that contribute to parasite control. In this regard, extracts of Lantana camara (Verbenacea) have shown high biocidal potential against isolates of Trypanosoma cruzi and Leishmania braziliensis in vitro assays, although their effect on Tritrichomonas foetus has not been demonstrated yet. The available information on in vitro susceptibility of trichomonicidal drugs comes from the use of a diversity of methodologies and criteria, especially the observation of parasite motility under the optical microscope to assess their viability. Recently, in our laboratory, the use of flow cytometry has been described for the first time as a rapid and efficient method to evaluate the viability of T. foetus against metronidazole. The present study aimed to evaluate the cytostatic effect of L. camara extracts against T. foetus isolates by flow cytometry. Under aerobic conditions, IC
Identifiants
pubmed: 37100969
doi: 10.1007/s11259-023-10124-y
pii: 10.1007/s11259-023-10124-y
doi:
Substances chimiques
Metronidazole
140QMO216E
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1687-1695Informations de copyright
© 2023. The Author(s), under exclusive licence to Springer Nature B.V.
Références
Alonso J, Desmarchelier C (2014) Plantas medicinales autoctonas de la Argentina. Bases científicas para su aplicacion en atencion primaria de la salud. Corpus, Buenos Aires
Amaral RG, Baldissera MD, Grando TH, Couto JCM, Posser CP, Ramos AP, Monteiro SG (2016) Combination of the essential oil constituents α-pinene and β-caryophyllene as a potentiator of trypanocidal action on Trypanosoma evansi. J Appl Biomed 14(4):265–272. https://doi.org/10.1016/J.JAB.2016.04.004
doi: 10.1016/J.JAB.2016.04.004
Bader C, Chelladurai JJ, Thompson K, Hall C, Carlson SA, Brewer MT (2016) Evaluation of high-throughput assays for in vitro drug susceptibility testing of Tritrichomonas foetus trophozoites. Vet Parasitol 223:34–37. https://doi.org/10.1016/j.vetpar.2016.04.006
doi: 10.1016/j.vetpar.2016.04.006
pubmed: 27198774
Barros LM, Duarte AE, Morais-Braga MFB, Waczuk EP, Vega C, Leite NF, Menezes IRA, Coutinho HDM, Rocha JBT, Kamdem JP (2016) Chemical characterization and trypanocidal, leishmanicidal and cytotoxicity potential of Lantana camara L. (Verbenaceae) essential oil. Mol 21(2):209. https://doi.org/10.3390/molecules21020209
doi: 10.3390/molecules21020209
Begum S, Wahab A, Siddiqui BS (2003) Pentacyclic triterpenoids from the aerial parts of Lantana camara. Chem Pharm Bull 51(2):134–137. https://doi.org/10.1248/cpb.51.134
doi: 10.1248/cpb.51.134
Campero CM, Cobo ER (2006) Tritrichomonas foetus: patogénesis de la mortalidad embrionaria/fetal, caracterización de antígenos vacunales y respuesta inmune inducida. Rev Med Vet 87(2):47
Carvalho KP, Gadelha APR (2007) Effects of three benzimidazoles on growth, general morphology and ultrastructure of Tritrichomonas foetus. FEMS Microbiol Lett 275(2):292–300. https://doi.org/10.1111/j.1574-6968.2007.00897.x
doi: 10.1111/j.1574-6968.2007.00897.x
pubmed: 17825070
Deena MJ, Thoppil JE (2000) Antimicrobial activity of the essential oil of Lantana camara. Fitoter 71(4):453–455. https://doi.org/10.1016/S0367-326X(00)00140-4
doi: 10.1016/S0367-326X(00)00140-4
Diamond LS (1957) The establishment of various trichomonads of animals and man in axenic cultures. J Parasitol 43(4):488. https://doi.org/10.2307/3274682
doi: 10.2307/3274682
pubmed: 13463700
Dougnon G, Ito M (2019) Sedative effects of the essential oil from the leaves of Lantana camara occurring in the Republic of Benin via inhalation in mice. J Nat Med 74(1):159–169. https://doi.org/10.1007/S11418-019-01358-9
doi: 10.1007/S11418-019-01358-9
pubmed: 31446559
El Baroty GS, Goda HM, Khalifa EA, Abd El Baky HH (2014) Antimicrobial and antioxidant activities of leaves and flowers essential oils of egyptian Lantana camara L. Der Pharma Chem 6:246–255
Felleisen RSJ (1999) Host-parasite interaction in bovine infection with Tritrichomonas foetus. Microbes Infect 1(10):807–816. https://doi.org/10.1016/S1286-4579(99)80083-5
doi: 10.1016/S1286-4579(99)80083-5
pubmed: 10816086
Felleisen RSJ, Lambelet N, Bachmann P, Nicolet J, Müller N, Gottstein B (1998) Detection of Tritrichomonas foetus by PCR and DNA enzyme immunoassay based on rRNA gene unit sequences. J Clin Microbiol 36(2):513–519. https://doi.org/10.1128/jcm.36.2.513-519.1998
doi: 10.1128/jcm.36.2.513-519.1998
pubmed: 9466768
pmcid: 104569
Filho RBO, Malta KC, Borges JM, Oliveira PRF, Filho GJS, Nascimento GG, Mota RA, Júnior JWP (2018) Prevalence and risk factors associated with Tritrichomonas foetus infection in cattle in the state of Paraíba, Brazil. Acta Parasitol 63(2):346–353. https://doi.org/10.1515/ap-2018-0039
doi: 10.1515/ap-2018-0039
pubmed: 29654678
Hairgrove TB, Thompson JA, Rocha JN, Vinacur M, Roberts C, Pier GB, Cywes-Bentley C (2020) Failure of a novel surface polysaccharide targeting vaccine to prevent Tritrichomonas foetus infection in beef cattle. American Association of Bovine Practitioners Proceedings of the Annual Conference 53(2):368–368. https://doi.org/10.21423/AABPPRO20208112
Hashemi N, Ommi D, Kheyri P, Khamesipour F, Setzer WN, Benchimol M (2021) A review study on the anti-trichomonas activities of medicinal plants. Int J Parasitol: Drugs and Drug Resist 15:92–104. https://doi.org/10.1016/J.IJPDDR.2021.01.002
doi: 10.1016/J.IJPDDR.2021.01.002
Honigberg BM, Mattern CFT, Daniel WA (1971) Fine structure of the mastigont system in Tritrichomonas foetus (Riedmüller). J Protozool 18(2):183–198. https://doi.org/10.1111/j.1550-7408.1971.tb03306.x
doi: 10.1111/j.1550-7408.1971.tb03306.x
pubmed: 5091276
Kather EJ, Marks SL, Kass PH (2007) Determination of the in vitro susceptibility of feline Tritrichomonas foetus to 5 antimicrobial agents. J Vet Intern Med 21(5):966–970. https://doi.org/10.1111/j.1939-1676.2007.tb03050.x
doi: 10.1111/j.1939-1676.2007.tb03050.x
pubmed: 17939550
Kulda J (1999) Trichomonads, hydrogenosomes and drug resistance. Int J Parasitol 29(2):199–212. https://doi.org/10.1016/S0020-7519(98)00155-6
doi: 10.1016/S0020-7519(98)00155-6
pubmed: 10221623
Kulda J, Čerkasov J, Demeš P, Čerkasovová A (1984) Tritrichomonas foetus: stable anaerobic resistance to metronidazole in vitro. Exp Parasitol 57(1):93–103. https://doi.org/10.1016/0014-4894(84)90068-7
doi: 10.1016/0014-4894(84)90068-7
pubmed: 6692888
Kumar VP, Chauhan NS, Padh H, Rajani M (2006) Search for antibacterial and antifungal agents from selected indian medicinal plants. J Ethnopharmacol 107(2):182–188. https://doi.org/10.1016/j.jep.2006.03.013
doi: 10.1016/j.jep.2006.03.013
pubmed: 16678369
Laxminarayan R et al (2013) Antibiotic resistance- the need for global solutions. Lancet Infect Dis 13(12):1057–1098. https://doi.org/10.1016/S1473-3099(13)70318-9
doi: 10.1016/S1473-3099(13)70318-9
pubmed: 24252483
Liu J, Kanetake S, Wu YH, Tam C, Cheng LW, Land KM, Friedman M (2016) Antiprotozoal effects of the tomato tetrasaccharide glycoalkaloid tomatine and the aglycone tomatidine on mucosal trichomonads. J Agric Food Chem 64(46):8806–8810. https://doi.org/10.1021/acs.jafc.6b04030
doi: 10.1021/acs.jafc.6b04030
pubmed: 27934291
Love D, Fajt VR, Hairgrove T, Jones M, Thompson JA (2017) Metronidazole for the treatment of Tritrichomonas foetus in bulls. BMC Vet Res 13:1–6
doi: 10.1186/s12917-017-0999-2
Madigan MT, Martinko JM, Bender KS, Buckley DH, Stahl DA (2015) Brock. Biología de los microorganismos. Pearson, Madrid
Mardones FO, Perez AM, Martínez A, Carpenter TE (2008) Risk factors associated with Tritrichomonas foetus infection in beef herds in the Province of Buenos Aires. Argentina Vet Parasitol 153(3–4):231–237. https://doi.org/10.1016/j.vetpar.2008.01.038
doi: 10.1016/j.vetpar.2008.01.038
pubmed: 18337015
Medeiros LBP et al (2012) Chemical constituents and evaluation of cytotoxic and antifungal activity of Lantana camara essential oils. Rev Bras Farmacogn 22(6):1259–1267. https://doi.org/10.1590/S0102-695X2012005000098
doi: 10.1590/S0102-695X2012005000098
Meingassner JG, Mieth H, Czok R, Lindmark DG, Müller M (1978) Assay conditions and the demonstration of nitroimidazole resistance in Tritrichomonas foetus. Antimicrob Agents Chemother 13(1):1–3. https://doi.org/10.1128/AAC.13.1.1
doi: 10.1128/AAC.13.1.1
pubmed: 626482
pmcid: 352174
Misra L, Saikia AK (2011) Chemotypic variation in indian Lantana camara essential oil. J Essent Oil Res 23(3):1–5. https://doi.org/10.1080/10412905.2011.9700449
doi: 10.1080/10412905.2011.9700449
Nea F et al (2020) Composition, seasonal variation, and biological activities of Lantana camara essential oils from Côte d’Ivoire. Mol 25(10). https://doi.org/10.3390/molecules25102400
Nisha, Kumar K, Bhargava G, Land KM, Chang KH, Arora R, Sen S, Kumar V (2014) N-Propargylated isatin-mannich mono- and bis-adducts: synthesis and preliminary analysis of in vitro activity against Tritrichomonas foetus. Eur J Med Chem 74:657–663. https://doi.org/10.1016/j.ejmech.2014.01.015
doi: 10.1016/j.ejmech.2014.01.015
Rae DO, Crews JE, Greiner EC, Donovan GA (2004) Epidemiology of Tritrichomonas foetus in beef bull populations in Florida. Theriogenology 61(4):605–618. https://doi.org/10.1016/S0093-691X(03)00236-X
doi: 10.1016/S0093-691X(03)00236-X
pubmed: 14698052
Rivero MB, Luque ME, Abdala ME, Luna BE, Di Lullo D, Carranza PG, Rivero FD (2019) Flow cytometry evaluation of in vitro susceptibility of bovine isolates of Tritrichomonas foetus to metronidazole. Vet Parasitol 267:84–89. https://doi.org/10.1016/j.vetpar.2019.02.004
doi: 10.1016/j.vetpar.2019.02.004
pubmed: 30878091
Seth R, Mohan M, Singh P, Haider SZ, Gupta S, Bajpai I, Singh D, Dobhal R (2012) Chemical composition and antibacterial properties of the essential oil and extracts of Lantana camara Linn. From Uttarakhand (India). Asian Pac J Trop Biomed 2(3 suppl):S1407–S1411. https://doi.org/10.1016/S2221-1691(12)60426-2
doi: 10.1016/S2221-1691(12)60426-2
Shah M, Alharby HF, Hakeem KR (2020) Lantana camara: a comprehensive review on phytochemistry, ethnopharmacology and essential oil composition. Lett Appl Nano Biomed Sci 9(3):1199–1207. https://doi.org/10.33263/LIANBS93.11991207
doi: 10.33263/LIANBS93.11991207
Vázquez F, García MJ, Pérez F, Palacio V (2001) Trichomonas vaginalis: Tratamiento y resistencia a nitroimidazoles. Enferm Infecc Microbiol Clin 19:114–124. https://doi.org/10.1016/S0213-005X(01)72580-3
doi: 10.1016/S0213-005X(01)72580-3
pubmed: 11333589
Villalobos AP, Barrero LI, Rivera SM, Ovalle MV, Valera D (2014) Vigilancia de infecciones asociadas a la atención en salud, resistencia bacteriana y consumo de antibióticos en hospitales de alta complejidad, Colombia, 2011. Biomedica 34:67–80. https://doi.org/10.7705/biomedica.v34i0.1698
doi: 10.7705/biomedica.v34i0.1698
pubmed: 24968038