Selected Approaches to Disrupting Protein-Protein Interactions within the MAPK/RAS Pathway.
KRAS
MAPK
RAS
X-ray crystallography
protein–protein interactions
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
17 Apr 2023
17 Apr 2023
Historique:
received:
24
03
2023
revised:
11
04
2023
accepted:
12
04
2023
medline:
1
5
2023
pubmed:
28
4
2023
entrez:
28
4
2023
Statut:
epublish
Résumé
Within the MAPK/RAS pathway, there exists a plethora of protein-protein interactions (PPIs). For many years, scientists have focused efforts on drugging KRAS and its effectors in hopes to provide much needed therapies for patients with
Identifiants
pubmed: 37108538
pii: ijms24087373
doi: 10.3390/ijms24087373
pmc: PMC10139024
pii:
doi:
Substances chimiques
Proto-Oncogene Proteins p21(ras)
EC 3.6.5.2
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
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