In Vitro-In Vivo Correlation of Posaconazole-Amphotericin B Combination against
Candida albicans
amphotericin B
combination therapy
in vitro–in vivo correlation
posaconazole
Journal
Journal of fungi (Basel, Switzerland)
ISSN: 2309-608X
Titre abrégé: J Fungi (Basel)
Pays: Switzerland
ID NLM: 101671827
Informations de publication
Date de publication:
01 Apr 2023
01 Apr 2023
Historique:
received:
25
02
2023
revised:
27
03
2023
accepted:
29
03
2023
medline:
28
4
2023
pubmed:
28
4
2023
entrez:
28
4
2023
Statut:
epublish
Résumé
The in vitro/in vivo correlation of antifungal combination testing is necessary in order to assess the efficacy of combination regimens. We, therefore, attempted to correlate in vitro chequerboard testing of posaconazole (POS) and amphotericin B (AMB) with the in vivo outcome of combination therapy against experimental candidiasis in a neutropenic murine model. The AMB + POS combination was tested against a
Identifiants
pubmed: 37108889
pii: jof9040434
doi: 10.3390/jof9040434
pmc: PMC10146624
pii:
doi:
Types de publication
Journal Article
Langues
eng
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