How Can We Best Measure Frailty in Cardiosurgical Patients?

cardiosurgery frailty outcome risk score

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
20 Apr 2023
Historique:
received: 20 02 2023
revised: 14 03 2023
accepted: 29 03 2023
medline: 28 4 2023
pubmed: 28 4 2023
entrez: 28 4 2023
Statut: epublish

Résumé

Frailty is gaining importance in cardiothoracic surgery and is a risk factor for adverse outcomes and mortality. Various frailty scores have since been developed, but there is no consensus which to use for cardiac surgery. In an all-comer prospective study of patients presenting for cardiac surgery, we assessed frailty and analyzed complication rates in hospital and 1-year mortality, as well as laboratory markers before and after surgery. 246 included patients were analyzed. A total of 16 patients (6.5%) were frail, and 130 patients (52.85%) were pre-frail, summarized in the frail group (FRAIL) and compared to the non-frail patients (NON-FRAIL). The mean age was 66.5 ± 9.05 years, 21.14% female. The in-hospital mortality rate was 4.88% and the 1-year mortality rate was 6.1%. FRAIL patients stayed longer in hospital (FRAIL 15.53 ± 8.5 days vs. NON-FRAIL 13.71 ± 8.94 days, frailty parameters with the highest predictive value as well as ease of use could be added to the EuroSCORE.

Sections du résumé

BACKGROUND BACKGROUND
Frailty is gaining importance in cardiothoracic surgery and is a risk factor for adverse outcomes and mortality. Various frailty scores have since been developed, but there is no consensus which to use for cardiac surgery.
METHODS METHODS
In an all-comer prospective study of patients presenting for cardiac surgery, we assessed frailty and analyzed complication rates in hospital and 1-year mortality, as well as laboratory markers before and after surgery.
RESULTS RESULTS
246 included patients were analyzed. A total of 16 patients (6.5%) were frail, and 130 patients (52.85%) were pre-frail, summarized in the frail group (FRAIL) and compared to the non-frail patients (NON-FRAIL). The mean age was 66.5 ± 9.05 years, 21.14% female. The in-hospital mortality rate was 4.88% and the 1-year mortality rate was 6.1%. FRAIL patients stayed longer in hospital (FRAIL 15.53 ± 8.5 days vs. NON-FRAIL 13.71 ± 8.94 days,
CONCLUSIONS CONCLUSIONS
frailty parameters with the highest predictive value as well as ease of use could be added to the EuroSCORE.

Identifiants

pubmed: 37109346
pii: jcm12083010
doi: 10.3390/jcm12083010
pmc: PMC10140958
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Interne Forschungsförderung Brandenburg Medical School
ID : Projekt PREDARF
Organisme : Land Brandenburg
ID : cluster cardiovascular health of the non-metropol region Brandenburg

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Auteurs

Magdalena L Laux (ML)

Department of Cardiovascular Surgery, Heart Center Brandenburg, University Hospital Brandenburg Medical School, Faculty of Health Sciences Brandenburg, 16321 Bernau, Germany.

Christian Braun (C)

Department of Cardiovascular Surgery, Heart Center Brandenburg, University Hospital Brandenburg Medical School, Faculty of Health Sciences Brandenburg, 16321 Bernau, Germany.

Filip Schröter (F)

Department of Cardiovascular Surgery, Heart Center Brandenburg, University Hospital Brandenburg Medical School, Faculty of Health Sciences Brandenburg, 16321 Bernau, Germany.

Daniela Weber (D)

Department of Molecular Toxicology, German Institute of Human Nutrition (DIfE), 14558 Nuthetal, Germany.

Aiman Moldasheva (A)

Department of Molecular Toxicology, German Institute of Human Nutrition (DIfE), 14558 Nuthetal, Germany.
Department of Biomedical Sciences, Nazarbayev University, Astana 010000, Kazakhstan.

Tilman Grune (T)

Department of Molecular Toxicology, German Institute of Human Nutrition (DIfE), 14558 Nuthetal, Germany.

Roya Ostovar (R)

Department of Cardiovascular Surgery, Heart Center Brandenburg, University Hospital Brandenburg Medical School, Faculty of Health Sciences Brandenburg, 16321 Bernau, Germany.

Martin Hartrumpf (M)

Department of Cardiovascular Surgery, Heart Center Brandenburg, University Hospital Brandenburg Medical School, Faculty of Health Sciences Brandenburg, 16321 Bernau, Germany.

Johannes Maximilian Albes (JM)

Department of Cardiovascular Surgery, Heart Center Brandenburg, University Hospital Brandenburg Medical School, Faculty of Health Sciences Brandenburg, 16321 Bernau, Germany.

Classifications MeSH