An Updated Review on the Role of Nanoformulated Phytochemicals in Colorectal Cancer.
chemotherapy
colorectal cancer
nanotechnology
phytochemicals
stress
Journal
Medicina (Kaunas, Lithuania)
ISSN: 1648-9144
Titre abrégé: Medicina (Kaunas)
Pays: Switzerland
ID NLM: 9425208
Informations de publication
Date de publication:
30 Mar 2023
30 Mar 2023
Historique:
received:
25
01
2023
revised:
24
03
2023
accepted:
27
03
2023
medline:
1
5
2023
pubmed:
28
4
2023
entrez:
28
4
2023
Statut:
epublish
Résumé
The most common cancer-related cause of death worldwide is colorectal cancer. It is initiated with the formation of polyps, which further cause the development of colorectal cancer in multistep phases. Colorectal cancer mortality is high despite recent treatment breakthroughs and a greater understanding of its pathophysiology. Stress is one of the major causes of triggering different cellular signalling cascades inside the body and which might turn toward the development of cancer. Naturally occurring plant compounds or phytochemicals are being studied for medical purposes. Phytochemicals' benefits are being analyzed for inflammatory illnesses, liver failure, metabolic disorders, neurodegenerative disorders, and nephropathies. Cancer treatment with fewer side effects and better outcomes has been achieved by combining phytochemicals with chemotherapy. Resveratrol, curcumin, and epigallocatechin-3-gallate have been studied for their chemotherapeutic and chemopreventive potentiality, but hydrophobicity, solubility, poor bioavailability, and target selectivity limit the clinical uses of these compounds. The therapeutic potential is maximized by utilizing nanocarriers such as liposomes, micelles, nanoemulsions, and nanoparticles to increase phytochemical bioavailability and target specificity. This updated literature review discusses the clinical limitations, increased sensitivity, chemopreventive and chemotherapeutic effects, and the clinical limitations of the phytochemicals.
Identifiants
pubmed: 37109643
pii: medicina59040685
doi: 10.3390/medicina59040685
pmc: PMC10143464
pii:
doi:
Substances chimiques
Liposomes
0
Curcumin
IT942ZTH98
Phytochemicals
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Références
Front Bioeng Biotechnol. 2020 Feb 11;8:50
pubmed: 32117930
Molecules. 2020 Dec 15;25(24):
pubmed: 33333788
Biomed Pharmacother. 2019 Sep;117:109142
pubmed: 31238258
Drug Discov Today. 2020 Aug;25(8):1307-1321
pubmed: 32554061
Expert Opin Drug Metab Toxicol. 2008 Aug;4(8):1035-52
pubmed: 18680439
Pharm Biol. 2017 Dec;55(1):620-635
pubmed: 27951737
Nutrients. 2017 Jun 03;9(6):
pubmed: 28587207
Carcinogenesis. 2018 May 3;39(5):669-680
pubmed: 29547900
J Nanosci Nanotechnol. 2011 Feb;11(2):1259-66
pubmed: 21456169
Biology (Basel). 2021 Mar 23;10(3):
pubmed: 33806918
Gut. 2023 Feb;72(2):338-344
pubmed: 36604116
Nutr Cancer. 2009;61(4):544-53
pubmed: 19838927
Mater Today (Kidlington). 2019 Dec;31:86-99
pubmed: 32831620
Artif Cells Nanomed Biotechnol. 2018;46(sup2):295-305
pubmed: 30043651
Drug Resist Updat. 2015 May;20:39-70
pubmed: 26027741
Nanoscale Res Lett. 2021 Dec 5;16(1):173
pubmed: 34866166
Photodiagnosis Photodyn Ther. 2022 Mar;37:102697
pubmed: 34936918
Trends Pharmacol Sci. 2009 Feb;30(2):85-94
pubmed: 19110321
Toxicol In Vitro. 2011 Dec;25(8):1557-67
pubmed: 21640813
Mutat Res. 2009 Mar 31;674(1-2):36-44
pubmed: 18977455
Int Immunopharmacol. 2020 Apr;81:106288
pubmed: 32062075
Biomaterials. 2014 Mar;35(10):3365-83
pubmed: 24439402
Cell Oncol (Dordr). 2019 Aug;42(4):405-421
pubmed: 30980365
Mol Pharm. 2008 Jul-Aug;5(4):505-15
pubmed: 18672949
Antioxidants (Basel). 2021 Sep 14;10(9):
pubmed: 34573087
Int J Nanomedicine. 2015 Mar 16;10:2051-63
pubmed: 25844036
Nutrients. 2019 Oct 05;11(10):
pubmed: 31590362
Molecules. 2017 Aug 23;22(9):
pubmed: 28832535
JAMA. 2021 Feb 16;325(7):669-685
pubmed: 33591350
Med Oncol. 2021 Nov 15;39(1):12
pubmed: 34779924
Carcinogenesis. 2014 Feb;35(2):415-23
pubmed: 24072771
Basic Clin Pharmacol Toxicol. 2007 Oct;101(4):277-85
pubmed: 17845510
Anticancer Res. 2016 Apr;36(4):1631-9
pubmed: 27069140
Biotechnol Rep (Amst). 2021 May 18;30:e00633
pubmed: 34094892
Pharmaceutics. 2022 Jun 07;14(6):
pubmed: 35745786
Apoptosis. 2011 Feb;16(2):184-97
pubmed: 21107704
Adv Drug Deliv Rev. 2002 Sep 13;54(5):631-51
pubmed: 12204596
Environ Health Perspect. 1994 Dec;102 Suppl 10:123-9
pubmed: 7705286
Expert Opin Drug Deliv. 2012 Apr;9(4):367-81
pubmed: 22400808
Nutr Cancer. 2017 May-Jun;69(4):623-631
pubmed: 28323438
Int J Mol Sci. 2015 Feb 03;16(2):3350-76
pubmed: 25654230
PLoS One. 2011 Apr 29;6(4):e18695
pubmed: 21559086
Biochem Pharmacol. 2020 Apr;174:113776
pubmed: 31874145
Cancer Chemother Pharmacol. 2013 Mar;71(3):555-64
pubmed: 23212117
J Control Release. 2015 Feb 28;200:138-57
pubmed: 25545217
Tumori. 2003 May-Jun;89(3):237-49
pubmed: 12908776
J Nanobiotechnology. 2021 Nov 27;19(1):392
pubmed: 34838036
Nanomedicine (Lond). 2016 Sep;11(18):2443-56
pubmed: 27529192
Carcinogenesis. 2015 Mar;36(3):355-67
pubmed: 25653233
Medicine (Baltimore). 2017 Feb;96(5):e5521
pubmed: 28151847
Plant Cell. 2011 Jul;23(7):2483-97
pubmed: 21803940
World J Gastroenterol. 2022 Jul 7;28(25):2867-2880
pubmed: 35978871
Mol Nutr Food Res. 2008 Jun;52 Suppl 1:S52-61
pubmed: 18504708
Nat Prod Rep. 2020 Jun 24;37(6):827-860
pubmed: 32519686
Int J Oncol. 2012 Apr;40(4):1020-8
pubmed: 22218562
Semin Cancer Biol. 2021 Aug;73:321-330
pubmed: 32942023
Nature. 2000 Oct 12;407(6805):770-6
pubmed: 11048727
Cancers (Basel). 2020 Jan 15;12(1):
pubmed: 31952210
Crit Rev Food Sci Nutr. 2020;60(20):3522-3546
pubmed: 31822111
J Anim Sci. 2009 Apr;87(14 Suppl):E101-8
pubmed: 18791134
Anticancer Res. 2018 Nov;38(11):6247-6252
pubmed: 30396944
Urol Oncol. 2008 Jan-Feb;26(1):57-64
pubmed: 18190833
Gastroenterology. 2020 Jan;158(2):418-432
pubmed: 31394083
FEMS Immunol Med Microbiol. 2005 Mar 1;43(3):407-12
pubmed: 15708315
Mol Cancer Ther. 2013 Dec;12(12):2640-50
pubmed: 24126433
Proc Nutr Soc. 2011 Feb;70(1):47-56
pubmed: 21067630
Biochim Biophys Acta Gen Subj. 2017 Feb;1861(2):431-440
pubmed: 27760368
Phytother Res. 2021 Aug;35(8):4194-4214
pubmed: 33749909
Biofouling. 2016 Oct;32(9):1007-16
pubmed: 27552663
Carcinogenesis. 2010 Nov;31(11):1991-8
pubmed: 20724373
Neuro Oncol. 2019 Mar 18;21(4):517-526
pubmed: 30277536
FEMS Immunol Med Microbiol. 2005 Feb 1;43(2):295-300
pubmed: 15681161
Molecules. 2020 Mar 20;25(6):
pubmed: 32244860
Colloids Surf B Biointerfaces. 2016 Aug 1;144:1-7
pubmed: 27060664
Anim Nutr. 2020 Jun;6(2):115-123
pubmed: 32542190
Angew Chem Int Ed Engl. 2014 Apr 7;53(15):3796-827
pubmed: 24677743
Int J Nanomedicine. 2006;1(3):297-315
pubmed: 17717971
Small. 2015 Jan 27;11(4):392-413
pubmed: 25367307
Life Sci. 2020 Sep 15;257:118122
pubmed: 32702446
Int J Oncol. 2014 Nov;45(5):1913-20
pubmed: 25109615
Jpn J Clin Oncol. 2020 May 5;50(5):535-542
pubmed: 32083298
Drug Des Devel Ther. 2017 May 25;11:1605-1621
pubmed: 28579758
Int J Cancer. 2016 Dec 1;139(11):2436-46
pubmed: 27522007
Nat Rev Gastroenterol Hepatol. 2019 Dec;16(12):713-732
pubmed: 31455888
Int J Mol Sci. 2018 Sep 18;19(9):
pubmed: 30231546
Gut. 2017 Apr;66(4):683-691
pubmed: 26818619
Nanoscale Res Lett. 2019 Jun 4;14(1):193
pubmed: 31165329
J Clin Oncol. 2007 May 1;25(13):1658-64
pubmed: 17470858
Nanomedicine. 2018 Apr;14(3):1059-1071
pubmed: 29391211
World J Gastroenterol. 2015 Aug 21;21(31):9262-72
pubmed: 26309353
Anticancer Agents Med Chem. 2020;20(11):1288-1299
pubmed: 31429694
Clin Breast Cancer. 2003 Nov;4 Suppl 2:S76-83
pubmed: 14667278
Tumour Biol. 2014 Nov;35(11):11483-8
pubmed: 25128065
J Mol Model. 2021 Jul 26;27(8):231
pubmed: 34312718
Gastroenterology. 2020 Jan;158(1):46-48
pubmed: 31770524
Mol Pharm. 2017 Dec 4;14(12):4431-4441
pubmed: 29094948
Mol Carcinog. 2015 Oct;54(10):1096-109
pubmed: 24838344
Curr Med Chem. 2018;25(34):4224-4268
pubmed: 28875844
J Pharmacol Exp Ther. 2006 Aug;318(2):484-94
pubmed: 16632641
Indian J Exp Biol. 1998 Sep;36(9):891-5
pubmed: 9854429
Asian Pac J Cancer Prev. 2014;15(16):6463-75
pubmed: 25169472
Acta Biomater. 2021 Jun;127:24-40
pubmed: 33812076
Membranes (Basel). 2020 May 03;10(5):
pubmed: 32375292
Biotechnol Adv. 2016 Jul-Aug;34(4):343-353
pubmed: 27071534
World J Gastroenterol. 2020 Feb 14;26(6):562-597
pubmed: 32103869
Mater Sci Eng C Mater Biol Appl. 2020 Apr;109:110550
pubmed: 32228916
Clin Nutr. 2018 Apr;37(2):452-458
pubmed: 28209333
Oncol Rep. 2015 Nov;34(5):2782-9
pubmed: 26351877
Adv Drug Deliv Rev. 2013 Nov;65(13-14):1686-98
pubmed: 24055719
J Mater Chem B. 2020 Aug 5;8(30):6333-6351
pubmed: 32633311
Arch Toxicol. 2007 Oct;81(10):719-28
pubmed: 17673978
J Mater Chem B. 2020 Feb 14;8(6):1128-1138
pubmed: 31971528
Pharm Res. 2008 Jul;25(7):1552-62
pubmed: 18196205
Nutr Clin Pract. 2012 Oct;27(5):599-612
pubmed: 22878362
Int J Mol Sci. 2020 Mar 29;21(7):
pubmed: 32235371
J Pharm Pharmacol. 2022 Jun 9;74(6):812-842
pubmed: 35199159
Colloids Surf B Biointerfaces. 2021 Jan;197:111389
pubmed: 33075659
Molecules. 2022 May 18;27(10):
pubmed: 35630713
Nat Rev Mol Cell Biol. 2007 Oct;8(10):813-24
pubmed: 17848967
Mol Cells. 2013 Jun;35(6):526-32
pubmed: 23686430
Recent Pat Inflamm Allergy Drug Discov. 2011 Sep;5(3):200-20
pubmed: 21827399
Front Immunol. 2020 Jul 10;11:1407
pubmed: 32754151
Biomed Res Int. 2013;2013:725710
pubmed: 23762854
Oncotarget. 2017 Nov 3;9(1):1380-1402
pubmed: 29416702
Cancers (Basel). 2021 Apr 22;13(9):
pubmed: 33922197
Clin Colorectal Cancer. 2016 Sep;15(3):195-203
pubmed: 26964802
Int J Nanomedicine. 2020 Feb 21;15:1239-1252
pubmed: 32110020
Biomed Pharmacother. 2019 May;113:108703
pubmed: 30870719
Biomed Res Int. 2014;2014:761264
pubmed: 24587990
Toxicol Lett. 2014 Nov 18;231(1):82-91
pubmed: 25256401
J Colloid Interface Sci. 2016 Jan 15;462:368-74
pubmed: 26479200
Small. 2013 May 27;9(9-10):1521-32
pubmed: 23019091
J Nat Prod. 2014 May 23;77(5):1130-4
pubmed: 24828199
Med Oncol. 2020 Apr 17;37(6):49
pubmed: 32303850
Biomedicines. 2020 Sep 12;8(9):
pubmed: 32932737
Nano Converg. 2019 Jul 15;6(1):23
pubmed: 31304563
Molecules. 2019 Nov 21;24(23):
pubmed: 31766544
Curr Opin Clin Nutr Metab Care. 2002 Nov;5(6):685-94
pubmed: 12394645
Gastrointest Endosc Clin N Am. 2022 Apr;32(2):177-194
pubmed: 35361330
Oncol Lett. 2019 Jul;18(1):487-498
pubmed: 31289520
J Cancer. 2020 May 18;11(15):4521-4533
pubmed: 32489469
Curr Pharm Des. 2013;19(11):1994-2010
pubmed: 23116309
Semin Cancer Biol. 2022 May;80:306-339
pubmed: 32610149
Adv Drug Deliv Rev. 2013 Jan;65(1):71-9
pubmed: 23088862
Biochimie. 2010 Sep;92(9):1242-51
pubmed: 20211678
Nano Today. 2010 Dec 1;5(6):524-539
pubmed: 22473061
Transl Oncol. 2021 Oct;14(10):101174
pubmed: 34243011
J Pharmacol Sci. 2015 May;128(1):27-34
pubmed: 26003085
Adv Drug Deliv Rev. 2014 Feb;66:2-25
pubmed: 24270007
Nanomedicine. 2014 Nov;10(8):1619-26
pubmed: 24965756
J Biomed Nanotechnol. 2016 May;12(5):973-85
pubmed: 27305819
Mol Nutr Food Res. 2011 Apr;55(4):606-12
pubmed: 21462328