Altered Glycosylation in Progression and Management of Bladder Cancer.
Lewis’s antigen
N-glycosylation
O-glycosylation
T antigen
Tn antigen
bladder cancer
extracellular vesicles
glycosaminoglycans
mucins
tumor glycosylation
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
13 Apr 2023
13 Apr 2023
Historique:
received:
24
02
2023
revised:
05
04
2023
accepted:
11
04
2023
medline:
1
5
2023
pubmed:
28
4
2023
entrez:
28
4
2023
Statut:
epublish
Résumé
Bladder cancer (BC) is the 10th most common malignancy worldwide, with an estimated 573,000 new cases and 213,000 deaths in 2020. Available therapeutic approaches are still unable to reduce the incidence of BC metastasis and the high mortality rates of BC patients. Therefore, there is a need to deepen our understanding of the molecular mechanisms underlying BC progression to develop new diagnostic and therapeutic tools. One such mechanism is protein glycosylation. Numerous studies reported changes in glycan biosynthesis during neoplastic transformation, resulting in the appearance of the so-called tumor-associated carbohydrate antigens (TACAs) on the cell surface. TACAs affect a wide range of key biological processes, including tumor cell survival and proliferation, invasion and metastasis, induction of chronic inflammation, angiogenesis, immune evasion, and insensitivity to apoptosis. The purpose of this review is to summarize the current information on how altered glycosylation of bladder cancer cells promotes disease progression and to present the potential use of glycans for diagnostic and therapeutic purposes.
Identifiants
pubmed: 37110670
pii: molecules28083436
doi: 10.3390/molecules28083436
pmc: PMC10146225
pii:
doi:
Substances chimiques
Antigens, Tumor-Associated, Carbohydrate
0
Polysaccharides
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Jagiellonian University
ID : N18/DBS/000007
Références
Glycobiology. 2013 Feb;23(2):178-87
pubmed: 23035012
Adv Cancer Res. 2014;123:191-209
pubmed: 25081530
J Cancer. 2017 Apr 9;8(7):1137-1144
pubmed: 28607587
PLoS One. 2013 Oct 11;8(10):e76190
pubmed: 24146840
Adv Cancer Res. 2015;126:11-51
pubmed: 25727145
Clin Cancer Res. 2016 Mar 1;22(5):1274-83
pubmed: 26490312
J Urol. 2003 Jan;169(1):86-9
pubmed: 12478110
J Proteome Res. 2015 Feb 6;14(2):639-53
pubmed: 25536294
BMC Cancer. 2009 Oct 07;9:357
pubmed: 19811634
Int J Mol Sci. 2021 Jan 05;22(1):
pubmed: 33466384
Pharmacol Ther. 2018 Aug;188:1-11
pubmed: 29476772
Mol Med. 2022 Sep 14;28(1):115
pubmed: 36104770
Mol Oncol. 2014 May;8(3):753-65
pubmed: 24656965
Eur Urol. 2017 Jul;72(1):142-150
pubmed: 28408175
Crit Rev Oncol Hematol. 2018 Feb;122:98-122
pubmed: 29458795
Protein Cell. 2019 Aug;10(8):550-565
pubmed: 30478534
FEBS J. 2008 May;275(9):1939-48
pubmed: 18384383
Acta Biochim Pol. 2000;47(2):427-34
pubmed: 11051207
J Urol. 2006 Jan;175(1):90-3; discussion 93
pubmed: 16406879
Int J Mol Sci. 2020 Aug 20;21(17):
pubmed: 32825245
Cancer Metastasis Rev. 2019 Jun;38(1-2):223-236
pubmed: 30618016
Pharmacol Ther. 1991;50(3):285-90
pubmed: 1754603
ChemMedChem. 2020 Jul 20;15(14):1244-1257
pubmed: 32496638
J Zhejiang Univ Sci B. 2019 May;20(5):437-448
pubmed: 31090269
BMC Cancer. 2018 Feb 17;18(1):198
pubmed: 29454317
J Urol. 1990 Feb;143(2):285-8
pubmed: 2405185
Cancer Biochem Biophys. 1995 Nov;15(2):91-4
pubmed: 8590440
Br J Cancer. 2013 Oct 15;109(8):2106-14
pubmed: 24064971
Int J Mol Sci. 2017 Dec 06;18(12):
pubmed: 29210993
Am J Pathol. 2009 Mar;174(3):1027-36
pubmed: 19218337
Neoplasma. 2017;64(6):901-908
pubmed: 28895415
Oncotarget. 2018 Aug 3;9(60):31590-31605
pubmed: 30167081
Nat Commun. 2018 Aug 23;9(1):3380
pubmed: 30140003
Matrix Biol. 2019 Jan;75-76:220-259
pubmed: 29128506
Cancer Metastasis Rev. 2020 Sep;39(3):647-659
pubmed: 32488403
J Pineal Res. 2021 Oct;71(3):e12765
pubmed: 34487576
Biomolecules. 2016 Jul 30;6(3):
pubmed: 27483328
Biochim Biophys Acta. 2015 Jan;1850(1):236-52
pubmed: 24821013
Cancer Res. 2008 Jan 15;68(2):483-91
pubmed: 18199543
PLoS One. 2018 Jul 24;13(7):e0201208
pubmed: 30040854
J Inflamm Res. 2021 Mar 25;14:1069-1084
pubmed: 33790621
Oncogene. 2022 Jan;41(1):57-71
pubmed: 34675409
Oncol Rep. 2016 Nov;36(5):2852-2860
pubmed: 27599396
J Cell Biochem Suppl. 1992;16I:50-5
pubmed: 1305688
Can Urol Assoc J. 2009 Dec;3(6 Suppl 4):S193-8
pubmed: 20019984
Anal Quant Cytol Histol. 2011 Oct;33(5):277-82
pubmed: 22611755
J Urol. 2004 Sep;172(3):1123-6
pubmed: 15311054
Front Cell Infect Microbiol. 2022 Jun 14;12:856962
pubmed: 35774401
Theranostics. 2020 Aug 8;10(22):10078-10091
pubmed: 32929335
Cancer Sci. 2008 Jul;99(7):1304-10
pubmed: 18492092
Glycobiology. 2012 Jun;22(6):736-56
pubmed: 22183981
Med Sci (Basel). 2020 Mar 13;8(1):
pubmed: 32183076
Acta Biochim Pol. 2016;63(3):533-41
pubmed: 27474400
Int J Mol Sci. 2021 Dec 20;22(24):
pubmed: 34948435
Biochim Biophys Acta Gen Subj. 2017 Jan;1861(1 Pt A):3237-3257
pubmed: 27565356
Mol Oncol. 2013 Jun;7(3):719-31
pubmed: 23567325
CA Cancer J Clin. 2021 May;71(3):209-249
pubmed: 33538338
Eur Urol Focus. 2017 Feb;3(1):130-135
pubmed: 28720358
Medicine (Baltimore). 2022 Jul 1;101(26):e29760
pubmed: 35777025
J Innate Immun. 2017;9(3):281-299
pubmed: 28052300
Cancer Med. 2018 Aug;7(8):3763-3772
pubmed: 30022623
PLoS Negl Trop Dis. 2014 Dec 11;8(12):e3329
pubmed: 25502795
Cancer Metastasis Rev. 2021 Jun;40(2):575-588
pubmed: 33813658
Cancer Sci. 2020 Oct;111(10):3639-3652
pubmed: 32677159
Cancer. 2002 Feb 1;94(3):673-85
pubmed: 11857299
Biochim Biophys Acta. 2014 Aug;1846(1):142-51
pubmed: 24785432
Oncogene. 2010 May 20;29(20):2893-904
pubmed: 20348949
Cell Death Discov. 2020 Jul 27;6:65
pubmed: 32793395
Front Biosci (Elite Ed). 2012 Jan 01;4(1):499-515
pubmed: 22201891
Cancer Lett. 2017 Feb 28;387:32-45
pubmed: 26828132
Urol Res. 1983;11(4):163-6
pubmed: 6649197
Int J Urol. 2004 Jan;11(1):38-43
pubmed: 14678183
BMB Rep. 2012 Oct;45(10):554-9
pubmed: 23101508
Cancer Res. 2016 Mar 1;76(5):1273-83
pubmed: 26676748
Curr Opin Urol. 2010 Sep;20(5):393-7
pubmed: 20657288
Glycoconj J. 2021 Aug;38(4):459-474
pubmed: 33704667
Onco Targets Ther. 2021 Jan 15;14:445-454
pubmed: 33488099
Gastroenterology. 2018 Nov;155(5):1608-1624
pubmed: 30086262
Biochimie. 2005 Feb;87(2):133-42
pubmed: 15760705
Urol Oncol. 2017 Dec;35(12):675.e1-675.e8
pubmed: 28911924
Investig Clin Urol. 2016 Jun;57 Suppl 1:S77-88
pubmed: 27326410
Front Oncol. 2018 Dec 07;8:565
pubmed: 30619732
Cancer Cell. 2019 Jul 8;36(1):6-16
pubmed: 31287993
Mol Cancer Res. 2016 Dec;14(12):1288-1299
pubmed: 27655130
Urology. 2003 Jul;62(1):182-6
pubmed: 12837463
Cancer Cell. 2015 Oct 12;28(4):500-514
pubmed: 26461094
Glycoconj J. 2021 Feb;38(1):119-127
pubmed: 33411077
Anal Biochem. 2019 Nov 1;584:113390
pubmed: 31401005
Oncol Rep. 2012 Feb;27(2):409-15
pubmed: 22052369
Front Oncol. 2018 Feb 23;8:39
pubmed: 29527514
Cell Mol Biol Lett. 2020 Mar 10;25:17
pubmed: 32174982
Drug Des Devel Ther. 2018 Jul 02;12:1959-1975
pubmed: 29997433
J Clin Pathol. 2010 Apr;63(4):322-9
pubmed: 20354203
J Cancer. 2021 Jun 16;12(16):5066-5075
pubmed: 34234875
J Exp Med. 2020 Jan 6;217(1):
pubmed: 31645367
Acta Biochim Pol. 2002;49(3):643-50
pubmed: 12422234
Br J Cancer. 2021 Jan;124(1):76-90
pubmed: 33144696
Biochim Biophys Acta. 2002 Dec 19;1573(3):363-8
pubmed: 12417419
Bioscience. 2015 Aug 1;65(8):783-797
pubmed: 26955082
PLoS One. 2013 Nov 06;8(11):e80084
pubmed: 24223213
Chem Asian J. 2022 Aug 15;17(16):e202200342
pubmed: 35713953
Biomolecules. 2022 Nov 23;12(12):
pubmed: 36551160
Eur Urol. 2013 Jan;63(1):58-66
pubmed: 22917984
Int J Cancer. 2007 Apr 15;120(8):1712-20
pubmed: 17230515
Anticancer Res. 2014 Feb;34(2):735-44
pubmed: 24511007
Biochem J. 2014 May 15;460(1):69-78
pubmed: 24593306
J Cell Biol. 2015 Mar 30;208(7):869-80
pubmed: 25825515
Expert Opin Ther Targets. 2018 Aug;22(8):675-686
pubmed: 29999426
Eur J Cell Biol. 2006 Jan;85(1):47-57
pubmed: 16373174
Urologia. 2016 Jun 25;83 Suppl 1:11-4
pubmed: 27405344
Biochim Biophys Acta Mol Cell Res. 2023 Feb;1870(2):119409
pubmed: 36513218
J Biol Chem. 2005 Mar 25;280(12):11289-94
pubmed: 15653671
Int J Mol Sci. 2022 Nov 19;23(22):
pubmed: 36430846
Am J Clin Pathol. 2004 Jul;122(1):61-9
pubmed: 15272531
Biochim Biophys Acta. 2015 Dec;1856(2):211-25
pubmed: 26318196
Cancer Cell Int. 2002 Jun 18;2:6
pubmed: 12234377
Nat Rev Immunol. 2018 Mar;18(3):204-211
pubmed: 29398707
J Exp Clin Cancer Res. 2020 May 5;39(1):77
pubmed: 32370811
Scand J Urol Nephrol. 1996 Jun;30(3):173-7
pubmed: 8837247
BJU Int. 2015 Jan;115(1):163-5
pubmed: 24467768
Nat Commun. 2022 Dec 7;13(1):7539
pubmed: 36477196
Vojnosanit Pregl. 2012 Feb;69(2):147-50
pubmed: 22500368
Electrophoresis. 2010 Oct;31(19):3314-25
pubmed: 22216449
J Biol Chem. 2013 Mar 8;288(10):6921-9
pubmed: 23329828
N Biotechnol. 2019 Mar 25;49:77-87
pubmed: 30273682
Indian J Pathol Microbiol. 2017 Oct-Dec;60(4):510-514
pubmed: 29323063
BMB Rep. 2021 Jul;54(7):344-355
pubmed: 34154702
Oncotarget. 2016 Sep 27;7(39):63138-63157
pubmed: 27542232
Glycoconj J. 2018 Apr;35(2):217-231
pubmed: 29502191
Cancer. 2011 Mar 15;117(6):1197-209
pubmed: 20960509
Mol Oncol. 2017 Aug;11(8):895-912
pubmed: 28156048
Biochim Biophys Acta Gen Subj. 2020 Dec;1864(12):129726
pubmed: 32890705
Nat Rev Mol Cell Biol. 2017 Jul;18(7):452-465
pubmed: 28488703
Neoplasma. 2020 Jul;67(4):880-888
pubmed: 32305058
J Clin Pathol. 2008 May;61(5):658-64
pubmed: 17908805
Oncotarget. 2017 Apr 17;8(33):54506-54517
pubmed: 28903359
BMC Cancer. 2016 Sep 05;16:713
pubmed: 27595989
Theranostics. 2022 Mar 28;12(7):3150-3177
pubmed: 35547758
J Urol. 2000 Jan;163(1):348-56
pubmed: 10604388
Br J Cancer. 2004 Dec 13;91(12):2034-41
pubmed: 15583696
Pathol Int. 2022 Dec;72(12):606-616
pubmed: 36169278
Nat Rev Cancer. 2015 Sep;15(9):540-55
pubmed: 26289314
Eur Urol. 2004 Aug;46(2):200-8
pubmed: 15245814
Int J Mol Sci. 2019 Apr 22;20(8):
pubmed: 31013618
Cancer Treat Rev. 2019 Jun;76:10-21
pubmed: 31030123
Am J Pathol. 2023 Mar;193(3):350-361
pubmed: 36586479
Methods Mol Biol. 2021;2174:143-170
pubmed: 32813249
Am J Physiol Cell Physiol. 2022 Jun 1;322(6):C1187-C1200
pubmed: 35385322
Ann Surg Oncol. 2018 Nov;25(12):3518-3526
pubmed: 30128900
Eur J Pharm Sci. 2022 Jun 1;173:106167
pubmed: 35304859
Acta Biochim Pol. 2000;47(4):1159-70
pubmed: 11996105
EMBO Mol Med. 2013 Dec;5(12):1835-51
pubmed: 24142880
Proc Natl Acad Sci U S A. 2010 May 18;107(20):9228-33
pubmed: 20439703
Cancer. 2002 Jul 1;95(1):61-72
pubmed: 12115318
Nat Chem Biol. 2018 May;14(5):516-524
pubmed: 29632412
J Exp Clin Cancer Res. 2022 Jul 21;41(1):228
pubmed: 35864552
Clin Cancer Res. 2006 Apr 15;12(8):2506-11
pubmed: 16638859
Int J Clin Exp Pathol. 2014 Jul 15;7(8):4945-58
pubmed: 25197366
Clin Chim Acta. 2019 Apr;491:1-7
pubmed: 30629950
Oncol Lett. 2019 Aug;18(2):983-989
pubmed: 31423157
Glycoconj J. 2012 Dec;29(8-9):567-77
pubmed: 22644327
Front Oncol. 2022 Jul 21;12:883831
pubmed: 35936713
J Cancer Res Clin Oncol. 2001 Aug;127(8):512-9
pubmed: 11501752
J Biol Chem. 2019 Feb 15;294(7):2211-2231
pubmed: 30626734
Int J Mol Sci. 2021 Jun 18;22(12):
pubmed: 34207342
J Natl Cancer Inst. 2014 Apr 03;106(5):
pubmed: 24700805
J Urol. 1999 Apr;161(4):1316-23
pubmed: 10081901
Glycobiology. 2021 Dec 18;31(11):1444-1463
pubmed: 34350945
Hepatology. 1993 Jan;17(1):50-2
pubmed: 7678576
J Urol. 1985 Nov;134(5):978-81
pubmed: 3932680
Front Aging. 2021 Mar 12;1:620382
pubmed: 35822169
Annu Rev Biochem. 2011;80:825-58
pubmed: 21391816
Nat Commun. 2020 Dec 1;11(1):6139
pubmed: 33262351
Pathol Res Pract. 2018 Jan;214(1):1-6
pubmed: 29254798
Biomedicines. 2022 May 18;10(5):
pubmed: 35625898
Nature. 2001 Feb 8;409(6821):733-9
pubmed: 11217864
PLoS One. 2015 Nov 16;10(11):e0141253
pubmed: 26569621
FASEB J. 2020 Oct;34(10):13125-13139
pubmed: 32830349
Front Genet. 2014 May 23;5:145
pubmed: 24904645
Mol Aspects Med. 2021 Jun;79:100891
pubmed: 32861467
Clin Lab. 2012;58(5-6):579-83
pubmed: 22783592
FEBS J. 2013 May;280(10):2138-49
pubmed: 23351020
Appl Microbiol Biotechnol. 2012 May;94(4):887-905
pubmed: 22526796
Biomolecules. 2016 Apr 28;6(2):
pubmed: 27136596
J Urol. 2000 Oct;164(4):1398-404
pubmed: 10992422
Cell Rep. 2020 Oct 20;33(3):108276
pubmed: 33086064
FEBS J. 2022 Dec;289(24):7970-7986
pubmed: 34478583
Thromb Res. 2014 May;133 Suppl 2:S95-101
pubmed: 24862153
Cancers (Basel). 2021 Oct 26;13(21):
pubmed: 34771527
Glycoconj J. 2022 Apr;39(2):167-176
pubmed: 35089466
J Biochem. 2017 Jun 1;161(6):479-492
pubmed: 28011817
Tumori. 2010 May-Jun;96(3):452-9
pubmed: 20845808
Anal Biochem. 2021 Sep 1;628:114283
pubmed: 34102169
Cells. 2020 Feb 14;9(2):
pubmed: 32075174
Eur Urol. 2010 Jan;57(1):86-93
pubmed: 19345473
J Cancer Res Clin Oncol. 2008 Jun;134(6):659-65
pubmed: 18026991
PLoS One. 2014 Mar 26;9(3):e92742
pubmed: 24671186
Int J Cancer. 2007 Jun 15;120(12):2557-67
pubmed: 17315194
Eur J Pharmacol. 2021 Jul 15;903:174147
pubmed: 33961871
BMC Cancer. 2018 Nov 20;18(1):1141
pubmed: 30453909
Molecules. 2014 Dec 01;19(12):20073-90
pubmed: 25470275
J Exp Clin Cancer Res. 2021 Jun 9;40(1):191
pubmed: 34108014
EMBO J. 2011 Jun 28;30(15):3173-85
pubmed: 21712812
Pathol Oncol Res. 2016 Jul;22(3):443-7
pubmed: 26685886
J Biol Chem. 2022 Mar;298(3):101666
pubmed: 35104505
Front Endocrinol (Lausanne). 2013 Aug 12;4:99
pubmed: 23964270
Curr Cancer Drug Targets. 2021;21(2):132-152
pubmed: 33200711
Int J Oncol. 2012 Jun;40(6):1831-8
pubmed: 22446589
Cancer Res. 1992 Sep 1;52(17):4741-6
pubmed: 1511439
Prog Mol Biol Transl Sci. 2019;162:93-119
pubmed: 30905466
J Urol. 2014 May;191(5):1238-43
pubmed: 24333243
Glycobiology. 2017 Jan;27(1):3-49
pubmed: 27558841
Sci Transl Med. 2022 Jan 19;14(628):eabg3072
pubmed: 35044789
Cell. 2021 Jun 10;184(12):3109-3124.e22
pubmed: 34004145
BMC Urol. 2022 Jul 25;22(1):114
pubmed: 35879749
Biochem Biophys Res Commun. 2018 Sep 18;503(4):3142-3148
pubmed: 30143259