Magnetic Solid-Phase Microextraction Protocol Based on Didodecyldimethylammonium Bromide-Functionalized Nanoparticles for the Quantification of Epirubicin in Biological Matrices.
drug monitoring
epirubicin
magnetic solid-phase microextraction
nanoparticles
validation
Journal
Pharmaceutics
ISSN: 1999-4923
Titre abrégé: Pharmaceutics
Pays: Switzerland
ID NLM: 101534003
Informations de publication
Date de publication:
12 Apr 2023
12 Apr 2023
Historique:
received:
15
03
2023
revised:
30
03
2023
accepted:
11
04
2023
medline:
28
4
2023
pubmed:
28
4
2023
entrez:
28
4
2023
Statut:
epublish
Résumé
Due to epirubicin's (EPI) narrow therapeutic index and risk of cardiotoxicity, it is critical to monitor concentrations of this drug when being used to treat cancer patients. In this study, a simple and fast magnetic solid-phase microextraction (MSPME) protocol for the determination of EPI in plasma and urine samples is developed and tested. Experiments were performed using prepared Fe
Identifiants
pubmed: 37111712
pii: pharmaceutics15041227
doi: 10.3390/pharmaceutics15041227
pmc: PMC10145736
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : the European Union through the Eu-ropean Social Fund under the Operational Programme Knowledge Education Development 2014-2020.
ID : POWR.03.02.0 0-0 0- I014/17-00
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