Impact of sex and role of coronary artery disease in out-of-hospital cardiac arrest presenting with refractory ventricular arrhythmias.
OHCA
coronary artery disease
refractory ventricular arrhythmias
sex
shockable rhythm
Journal
Frontiers in cardiovascular medicine
ISSN: 2297-055X
Titre abrégé: Front Cardiovasc Med
Pays: Switzerland
ID NLM: 101653388
Informations de publication
Date de publication:
2023
2023
Historique:
received:
19
10
2022
accepted:
24
03
2023
medline:
28
4
2023
pubmed:
28
4
2023
entrez:
28
4
2023
Statut:
epublish
Résumé
There are limited data on sex-related differences in out-of hospital cardiac arrests (OHCAs) with refractory ventricular arrhythmias (VA) and, in particular, about their relationship with cardiovascular risk profile and severity of coronary artery disease (CAD). Aim of this study was to characterize sex-related differences in clinical presentation, cardiovascular risk profile, CAD prevalence, and outcome in OHCA victims presenting with refractory VA. All OHCAs with shockable rhythm that occurred between 2015 and 2019 in the province of Pavia (Italy) and in the Canton Ticino (Switzerland) were included. Out of 680 OHCAs with first shockable rhythm, 216 (33%) had a refractory VA. OHCA patients with refractory VA were younger and more often male. Males with refractory VA had more often a history of CAD (37% vs. 21%, In OHCA patients presenting with refractory VA the prognosis was significantly poorer for male patients. The refractoriness of arrhythmic events in the male population was probably due to a more complex cardiovascular profile and in particular due to a pre-existing CAD. In females, OHCA with refractory VA were less frequent and no correlation with a specific cardiovascular risk profile was observed.
Identifiants
pubmed: 37113702
doi: 10.3389/fcvm.2023.1074432
pmc: PMC10126276
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1074432Informations de copyright
© 2023 Caputo, Baldi, Krüll, Pongan, Cresta, Benvenuti, Cianella, Primi, Currao, Bendotti, Compagnoni, Gentile, Anselmi, Savastano, Klersy and Auricchio.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Eur Heart J. 2018 May 14;39(19):1664
pubmed: 29762703
Clin Exp Emerg Med. 2021 Mar;8(1):21-29
pubmed: 33845519
JACC Cardiovasc Imaging. 2009 Oct;2(10):1175-83
pubmed: 19833306
Circulation. 2019 Mar 19;139(12):e530-e552
pubmed: 30760026
Resuscitation. 2021 May;162:35-42
pubmed: 33581226
Transl Stroke Res. 2013 Aug;4(4):413-9
pubmed: 23930140
Lancet. 2020 Dec 5;396(10265):1807-1816
pubmed: 33197396
Circulation. 2015 Sep 29;132(13):1286-300
pubmed: 25391522
Circulation. 2004 Nov 23;110(21):3385-97
pubmed: 15557386
Resuscitation. 2017 Apr;113:33-38
pubmed: 28109996
JAMA. 2011 Jul 6;306(1):62-9
pubmed: 21730242
Eur Heart J Acute Cardiovasc Care. 2015 Aug;4(4):378-85
pubmed: 25326470
Resuscitation. 2020 Mar 1;148:218-226
pubmed: 32027980
Heart Rhythm. 2018 Jul;15(7):1031-1041
pubmed: 29550522
J Am Heart Assoc. 2016 Jun 13;5(6):
pubmed: 27412906
Resuscitation. 2018 Dec;133:1-4
pubmed: 30244190
Circ Cardiovasc Qual Outcomes. 2010 Jan;3(1):63-81
pubmed: 20123673
J Am Coll Cardiol. 2017 Aug 29;70(9):1109-1117
pubmed: 28838358
Int J Cardiol. 2015 Apr 15;185:93-4
pubmed: 25791100
J Transl Med. 2008 Jun 23;6:33
pubmed: 18573200
Resuscitation. 2017 May;114:73-78
pubmed: 28268186
Intern Emerg Med. 2021 Apr;16(3):765-775
pubmed: 33174152
Int J Cardiol. 2020 Jun 1;308:84-89
pubmed: 31980268
Atherosclerosis. 2015 Jul;241(1):208-10
pubmed: 25980844
Europace. 2016 Mar;18(3):398-404
pubmed: 26346920
Curr Cardiol Rev. 2018;14(2):109-114
pubmed: 29737259
J Am Heart Assoc. 2021 Nov 16;10(22):e021861
pubmed: 34779249
Resuscitation. 2019 Oct;143:189-195
pubmed: 31330199
Scand J Trauma Resusc Emerg Med. 2015 Apr 17;23:34
pubmed: 25928051
Resuscitation. 2020 Jul;152:39-49
pubmed: 32272235
Eur Heart J Cardiovasc Imaging. 2021 Sep 20;22(10):1149-1156
pubmed: 33247898