Combined personalized therapy for the treatment of multiple giant keloids: a case report and literature review.
keloid
skin grafting
wound healing
Journal
Annals of medicine and surgery (2012)
ISSN: 2049-0801
Titre abrégé: Ann Med Surg (Lond)
Pays: England
ID NLM: 101616869
Informations de publication
Date de publication:
Apr 2023
Apr 2023
Historique:
received:
11
10
2022
accepted:
12
02
2023
medline:
28
4
2023
pubmed:
28
4
2023
entrez:
28
4
2023
Statut:
epublish
Résumé
Keloids are the result of an abnormal wound-healing process and are associated with various risk factors. The majority of diagnoses are clinical. Successful treatment of keloid is challenging due to its nonregressing and recurring nature. We discuss the case of a 30-year-old mongoloid male who had multiple swellings over his body for the past 10 years. More striking are the giant keloids that are present over his bilateral scapulae. Diagnosis of keloid was made clinically. Smaller sessile lesions over his shoulder and upper limbs were subjected to intralesional 5-fluorouracil and triamcinolone injections, whereas the giant bilateral scapular keloids underwent excision and split skin grafting. Keloids usually present with firm and rubbery masses that extend beyond the site of the previous wound/injury. Keloids are diagnosed and evaluated clinically. Its differentiation from the hypertrophic scar is done based on the presence of multiple lesions beyond the site of the previous wound/injury. Treatment of keloids is difficult due to their nonregressing and recurring nature. Hence, the main goal of treatment is to tailor the therapy to the patient's needs such that the benefits outweigh the risks.
Identifiants
pubmed: 37113873
doi: 10.1097/MS9.0000000000000350
pmc: PMC10129174
doi:
Types de publication
Case Reports
Langues
eng
Pagination
1112-1115Informations de copyright
Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.
Déclaration de conflit d'intérêts
There are no conflicts of interest.
Références
Eur Arch Otorhinolaryngol. 2007 Dec;264(12):1497-508
pubmed: 17628822
BMC Dermatol. 2016 Sep 20;16(1):13
pubmed: 27646558
Niger J Clin Pract. 2019 Aug;22(8):1049-1054
pubmed: 31417046
Eur Surg Res. 2017;58(1-2):81-94
pubmed: 27974711
Int J Dermatol. 2021 Jun;60(6):661-671
pubmed: 32905614
Clin Dermatol. 2007 Jan-Feb;25(1):26-32
pubmed: 17276198
Br J Plast Surg. 2004 Mar;57(2):122-33
pubmed: 15037166
Clin Cosmet Investig Dermatol. 2018 Jul 24;11:387-396
pubmed: 30087573
Int J Surg. 2020 Dec;84:226-230
pubmed: 33181358
Medscape J Med. 2009;11(1):18
pubmed: 19295939
Arch Dermatol Res. 2014 Nov;306(9):803-8
pubmed: 25081927
Acta Derm Venereol. 2015 Sep;95(7):778-82
pubmed: 25805099
Br J Plast Surg. 2005 Jan;58(1):28-37
pubmed: 15629164
J Craniofac Surg. 2008 Jul;19(4):989-1006
pubmed: 18650721