Successful use of extracorporeal life support and hemadsorption in the context of venlafaxine intoxication requiring cardiopulmonary resuscitation: a case report.

Cardiopulmonary resuscitation CytoSorb® ECLS Takotsubo Venlafaxine intoxication

Journal

Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs
ISSN: 1619-0904
Titre abrégé: J Artif Organs
Pays: Japan
ID NLM: 9815648

Informations de publication

Date de publication:
28 Apr 2023
Historique:
received: 21 11 2022
accepted: 08 04 2023
medline: 28 4 2023
pubmed: 28 4 2023
entrez: 28 4 2023
Statut: aheadofprint

Résumé

Venlafaxine is a serotonin and noradrenalin reuptake inhibitor prescribed as an antidepressant. Overdose clinically manifests with neurological, cardiovascular and gastrointestinal abnormalities based on, amongst others, serotonin syndrome and can be life-threatening due to cardiovascular collapse. Besides immediate decontamination via gastric lavage and inhibition of enteral absorption through active charcoal, successful hemadsorption with CytoSorb

Identifiants

pubmed: 37115336
doi: 10.1007/s10047-023-01399-8
pii: 10.1007/s10047-023-01399-8
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2023. The Author(s).

Références

Cipriani A, et al. Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis. Lancet. 2018;391(10128):1357–66.
doi: 10.1016/S0140-6736(17)32802-7 pubmed: 29477251 pmcid: 5889788
Batista M, et al. The spectrum of acute heart failure after venlafaxine overdose. Clin Toxicol (Phila). 2013;51(2):92–5.
doi: 10.3109/15563650.2012.763133 pubmed: 23301719
Shelton RC. Serotonin and norepinephrine reuptake inhibitors. Handb Exp Pharmacol. 2019;250:145–80.
doi: 10.1007/164_2018_164 pubmed: 30838456
Höjer J, Hulting J, Salmonson H. Fatal cardiotoxicity induced by venlafaxine overdosage. Clin Toxicol (Phila). 2008;46(4):336–7.
doi: 10.1080/15563650701358755 pubmed: 18363134
Neil CJ, et al. Occurrence of Tako-Tsubo cardiomyopathy in association with ingestion of serotonin/noradrenaline reuptake inhibitors. Heart Lung Circ. 2012;21(4):203–5.
doi: 10.1016/j.hlc.2011.12.004 pubmed: 22285074
Christoph M, et al. Broken heart syndrome: Tako Tsubo cardiomyopathy associated with an overdose of the serotonin-norepinephrine reuptake inhibitor venlafaxine. Eur Neuropsychopharmacol. 2010;20(8):594–7.
doi: 10.1016/j.euroneuro.2010.03.009 pubmed: 20451358
Pancrazio JJ, et al. Inhibition of neuronal Na+ channels by antidepressant drugs. J Pharmacol Exp Ther. 1998;284(1):208–14.
pubmed: 9435180
Khalifa M, Daleau P, Turgeon J. Mechanism of sodium channel block by venlafaxine in guinea pig ventricular myocytes. J Pharmacol Exp Ther. 1999;291(1):280–4.
pubmed: 10490914
Forsberg S, Abazi L, Forsman P. Successful use of extended cardiopulmonary resuscitation followed by extracorporeal oxygenation after venlafaxine-induced takotsubo cardiomyopathy and cardiac arrest: a case report. J Med Case Rep. 2021;15(1):485.
doi: 10.1186/s13256-021-03031-w pubmed: 34579764 pmcid: 8477521
Schroeder I, et al. Venlafaxine intoxication with development of takotsubo cardiomyopathy: successful use of extracorporeal life support, intravenous lipid emulsion and CytoSorb®. Int J Artif Organs. 2017;40(7):358–60.
doi: 10.5301/ijao.5000595 pubmed: 28574114
Marquetand C, et al. The use of extracorporeal life support in a patient suffering from venlafaxine intoxication. A case report. J Crit Care Med (Targu Mures). 2020;6(2):120–3.
doi: 10.2478/jccm-2020-0014 pubmed: 32426519
Thomas A, et al. Intravenous lipid emulsion therapy and VA-ECMO rescue therapy for massive venlafaxine and clonazepam overdose. J Clin Toxicol. 2017;7:1–2.
doi: 10.4172/2161-0495.1000368
Masson R, et al. A comparison of survival with and without extracorporeal life support treatment for severe poisoning due to drug intoxication. Resuscitation. 2012;83(11):1413–7.
doi: 10.1016/j.resuscitation.2012.03.028 pubmed: 22469751
Reiter K, et al. In vitro removal of therapeutic drugs with a novel adsorbent system. Blood Purif. 2002;20(4):380–8.
doi: 10.1159/000063108 pubmed: 12169849
Kellum JA, Song M, Venkataraman R. Hemoadsorption removes tumor necrosis factor, interleukin-6, and interleukin-10, reduces nuclear factor-kappaB DNA binding, and improves short-term survival in lethal endotoxemia. Crit Care Med. 2004;32(3):801–5.
doi: 10.1097/01.CCM.0000114997.39857.69 pubmed: 15090965
Lang CN, et al. Use of the CytoSorb adsorption device in MDMA intoxication: a first-in-man application and in vitro study. Intensive Care Med Exp. 2020;8(1):21.
doi: 10.1186/s40635-020-00313-3 pubmed: 32542550 pmcid: 7295925
Mitrovic D, et al. Extracorporeal hemoadsorption with the CytoSorb device as a potential therapeutic option in severe intoxications: Review of the rationale and current clinical experiences. J Clin Pharm Ther. 2022;47(9):1444–51.
doi: 10.1111/jcpt.13724 pubmed: 35924306
Langford NJ, et al. Alternative venlafaxine kinetics in overdose. J Clin Pharm Ther. 2002;27(6):465–7.
doi: 10.1046/j.1365-2710.2002.00438.x pubmed: 12472987
Lee HM, et al. What are the adverse effects associated with the combined use of intravenous lipid emulsion and extracorporeal membrane oxygenation in the poisoned patient? Clin Toxicol (Phila). 2015;53(3):145–50.
doi: 10.3109/15563650.2015.1004582 pubmed: 25634667

Auteurs

Matthias Hoffmann (M)

Institute of Anesthesiology, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland. matthias.hoffmann@usz.ch.

Samira Akbas (S)

Institute of Anesthesiology, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland.

Rahel Kindler (R)

Institute of Intensive Care Medicine, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland.

Dominique Bettex (D)

Institute of Anesthesiology, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland.

Classifications MeSH