Associations between birth parameters and skin autofluorescence advanced glycation end products and ankle-brachial index in young adulthood: the Malmö Offspring Study.
Journal
Journal of hypertension
ISSN: 1473-5598
Titre abrégé: J Hypertens
Pays: Netherlands
ID NLM: 8306882
Informations de publication
Date de publication:
01 07 2023
01 07 2023
Historique:
medline:
2
6
2023
pubmed:
28
4
2023
entrez:
28
4
2023
Statut:
ppublish
Résumé
Low birth weight (LBW), advanced glycation end-products (AGE), and ankle-brachial index (ABI) have all been independently associated with risk of cardiovascular disease. Evidence is lacking on the effect of LBW on adult AGE, a marker of glucose metabolism, and ABI, a marker of peripheral atherosclerosis. The objective was to study these associations in a population-based cohort. Data from the Malmö Offspring Study, Sweden, were used for 2012 participants (958 men, 1054 women) born between 1973 and 2000, linked to the Medical Birth Register. General linear regression analysis (with β coefficients and 95% confidence intervals) was applied for associations between birth weight and skin auto-fluorescence (sf)AGE as well as mean ABI (right/left), before and after adjusting for gestational age, sex, glucose, lipids, smoking, BMI and SBP. The mean (SD) age of men was 29.3 (7.3) and of women 28.6 (7.3) years. There was an average 0.054 decrease in sfAGE value per 1 kg increase in birth weight (adjusted for gestational age and sex). Similarly, 1 kg increase in birth weight (adjusted for gestational age and confounders) was associated with an average 0.016 decrease in mean ABI. Birth weight, adjusted for gestational age and other confounding variables, is inversely associated with ABI in young adulthood, an age range when ABI may represent hemodynamic changes more than atherosclerosis, but for sfAGE, the association was attenuated upon further adjustment. These risk markers may, therefore, represent mediating pathways for early life factors affecting cardiovascular risk later in life.
Sections du résumé
BACKGROUND
Low birth weight (LBW), advanced glycation end-products (AGE), and ankle-brachial index (ABI) have all been independently associated with risk of cardiovascular disease. Evidence is lacking on the effect of LBW on adult AGE, a marker of glucose metabolism, and ABI, a marker of peripheral atherosclerosis. The objective was to study these associations in a population-based cohort.
METHODS
Data from the Malmö Offspring Study, Sweden, were used for 2012 participants (958 men, 1054 women) born between 1973 and 2000, linked to the Medical Birth Register. General linear regression analysis (with β coefficients and 95% confidence intervals) was applied for associations between birth weight and skin auto-fluorescence (sf)AGE as well as mean ABI (right/left), before and after adjusting for gestational age, sex, glucose, lipids, smoking, BMI and SBP.
RESULTS
The mean (SD) age of men was 29.3 (7.3) and of women 28.6 (7.3) years. There was an average 0.054 decrease in sfAGE value per 1 kg increase in birth weight (adjusted for gestational age and sex). Similarly, 1 kg increase in birth weight (adjusted for gestational age and confounders) was associated with an average 0.016 decrease in mean ABI.
CONCLUSION
Birth weight, adjusted for gestational age and other confounding variables, is inversely associated with ABI in young adulthood, an age range when ABI may represent hemodynamic changes more than atherosclerosis, but for sfAGE, the association was attenuated upon further adjustment. These risk markers may, therefore, represent mediating pathways for early life factors affecting cardiovascular risk later in life.
Identifiants
pubmed: 37115823
doi: 10.1097/HJH.0000000000003449
pii: 00004872-202307000-00015
doi:
Substances chimiques
Glycation End Products, Advanced
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1184-1190Informations de copyright
Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.
Références
Roth GA, Mensah GA, Johnson CO, Addolorato G, Ammirati E, Baddour LM, et al. GBD-NHLBI-JACC Global Burden of Cardiovascular Diseases Writing Group. Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019: update from the GBD 2019 Study. J Am Coll Cardiol 2020; 76 (25):2982–3021.
Knop MR, Geng TT, Gorny AW, Ding R, Li C, Ley SH, et al. Birth weight and risk of type 2 diabetes mellitus, cardiovascular disease, and hypertension in adults: a meta-analysis of 7 646 267 participants from 135 studies. J Am Heart Assoc 2018; 7 (23):e008870.
Mohseni R, Mohammed SH, Safabakhsh M, Mohseni F, Monfared ZS, Seyyedi J, et al. Birth weight and risk of cardiovascular disease incidence in adulthood: A dose-response meta-analysis. Curr Atherosclerosis Rep 2020; 22 (3):1–3.
Lacagnina S. The developmental origins of health and disease (DOHaD). Am J Lifestyle Med 2020; 14:47–50.
Brodszki J, Länne T, Marsál K, Ley D. Impaired vascular growth in late adolescence after intrauterine growth restriction. Circulation 2005; 111 (20):2623–2628.
Van Waateringe RP, Fokkens BT, Slagter SN, van der Klauw MM, van Vliet-Ostaptchouk JV, Graaff R, et al. Skin autofluorescence predicts incident type 2 diabetes, cardiovascular disease, and mortality in the general population. Diabetologia 2019; 62:269–280.
Paolillo FR, Mattos VS, Borghi-Silva A, Bagnato VS, de Castro Neto JC. Advanced glycation endproducts as biomarkers for risk of diabetes and cardiovascular diseases by skin autofluorescence: a noninvasive optical screening. Photobiomodul Photomed Laser Surg 2019; 37:168–174.
de Vos LC, Mulder DJ, Smit AJ, Dullaart RP, Kleefstra N, Lijfering WM, et al. Skin autofluorescence is associated with 5-year mortality and cardiovascular events in patients with peripheral artery disease. ATVB 2014; 34:933–938.
Boersma HE, van Waateringe RP, van der Klauw MM, Graaff R, Paterson AD, Smit AJ, Wolffenbuttel BHR. Skin autofluorescence predicts new cardiovascular disease and mortality in people with type 2 diabetes. BMC End Dis 2021; 21:14.
Arshi B, Chen J, Ikram MA, Zillikens MC, Kavousi M. Advanced glycation end-products, cardiac function and heart failure in the general population: The Rotterdam Study. Diabetologia 2022; 66:472–481.
Casey S, Lanting S, Oldmeadow C, Chuter V. The reliability of the ankle brachial index: a systematic review. J Foot Ankle Res 2019; 12:39.
Visonà A, De Paoli A, Fedeli U, Tonello D, Zalunardo B, Zanatta N, et al. Abnormal ankle-brachial index (ABI) predicts primary and secondary cardiovascular risk and cancer mortality. Eur J Intern Med 2020; 77:79–85.
Gu X, Man C, Zhang H, Fan Y. High ankle-brachial index and risk of cardiovascular or all-cause mortality: a meta-analysis. Atherosclerosis 2019; 282:29–36.
Alves-Cabratosa L, Comas-Cufí M, Ponjoan A, Garcia-Gil M, Martí-Lluch R, Blanch J, et al. Levels of ankle-brachial index and the risk of diabetes mellitus complications. BMJ Open Diab Res Care 2020; 8:e000977.
Xaplanteris P, Vlachopoulos C, Terentes-Printzios D, Abdelrasoul M, Ioakeimidis N, Dima I, et al. Are intermediate ankle-brachial index values important in hypertension? Insights from a large cohort of never-treated hypertensives. Artery Res 2014; 8:158.
Brunkwall L, Jönsson D, Ericson U, Hellstrand S, Kennbäck C, Östling G, et al. The Malmö Offspring Study (MOS): design, methods and first results. Eur J Epidemiol 2021; 36:103–116.
Odlind V, Haglund B, Pakkanen M, Otterblad Olausson P. Deliveries, mothers and newborn infants in Sweden, 1973–2000. Trends in obstetrics as reported to the Swedish Medical Birth Register. Acta Obstet Gynecol Scand 2003; 82:516–528.
Hedblad B, Nilsson P, Janzon L, Berglund G. Relation between insulin resistance and carotid intima-media thickness and stenosis in non-diabetic subjects. Results from a cross-sectional study in Malmö, Sweden. Diabet Med 2000; 17:299–307.
Manjer J, Carlsson S, Elmståhl S, Gullberg B, Janzon L, Lindström M, et al. The Malmö Diet and Cancer Study: representativity, cancer incidence and mortality in participants and non-participants. Eur J Cancer Prev 2001; 10:489–499.
Sperling J, Nilsson PM. Does early life programming influence arterial stiffness and central hemodynamics in adulthood? J Hypertens 2020; 38:481–488.
Jujić A, Östling G, Persson M, Engström G, Nilsson PM, Melander O S Magnusson##M. Skin autofluorescence as a measure of advanced glycation end product levels is associated with carotid atherosclerotic plaque burden in an elderly population. Diab Vasc Dis Res 2019; 16:466–473.
Khalid M, Petroianu G, Adem A. Advanced glycation end products and diabetes mellitus: mechanisms and perspectives. Biomolecules 2022; 12:542.
Xia Q, Cai H, Xiang YB, Zhou P, Li H, Yang G, et al. Prospective cohort studies of birth weight and risk of obesity, diabetes, and hypertension in adulthood among the Chinese population. J Diabetes 2019; 11:55–64.
Gluckman PD, Hanson MA, Cooper C, Thornburg KL. Effect of in utero and early-life conditions on adult health and disease. N Engl J Med 2008; 359:61–73.
Rønn PF, Jørgensen ME, Smith LS, Bjerregaard P, Dahl-Petersen IK, Larsen CVL, et al. Associations between birth weight and glucose intolerance in adulthood among Greenlandic Inuit. Diabetes Res Clin Pract 2019; 150:129–137.
van Eupen MG, Schram MT, van Sloten TT, Scheijen J, Sep SJ, van der Kallen CJ, et al. Skin autofluorescence and pentosidine are associated with aortic stiffening: The Maastricht Study. Hypertension 2016; 68:956–963.
Pan J, Bao X, Gonçalves I, Jujić A, Engström G. Skin autofluorescence, a measure of tissue accumulation of advanced glycation end products, is associated with subclinical atherosclerosis in coronary and carotid arteries. Atherosclerosis 2022; 345:26–32.
Almengló C, Rodriguez-Ruiz E, Alvarez E, López-Lago A, González-Juanatey JR, Garcia-Allut JL. Minimal invasive fluorescence methods to quantify advanced glycation end products (AGEs) in skin and plasma of humans. Methods 2022; 203:103–107.
Qu B, Liu Q, Li J. Systematic review of association between low ankle-brachial index and all-cause cardiovascular, or non-cardiovascular mortality. Cell Biochem Biophys 2015; 73:571–575.
Liew G, Wang JJ, Duncan BB, Klein R, Sharrett AR, Brancati F, et al. Atherosclerosis Risk in Communities Study. Low birthweight is associated with narrower arterioles in adults. Hypertens 2008; 51:933–938.
Rosenbaum D, Kachenoura N, Koch E, Paques M, Cluzel P, Redheuil A, et al. Relationships between retinal arteriole anatomy and aortic geometry and function and peripheral resistance in hypertensives. Hypertens Res 2016; 39:536–542.
Martyn CN, Gale CR, Jespersen S, Sherriff SB. Impaired fetal growth and atherosclerosis of carotid and peripheral arteries. Lancet 1998; 352 (9123):173–178.
Chiavaroli V, D’Adamo E, Giannini C, de Giorgis T, De Marco S, Chiarelli F, Mohn A. Serum levels of receptors for advanced glycation end products in normal-weight and obese children born small and large for gestational age. Diabetes Care 2012; 35:1361–1363.