Alternative splicing of
Journal
Science immunology
ISSN: 2470-9468
Titre abrégé: Sci Immunol
Pays: United States
ID NLM: 101688624
Informations de publication
Date de publication:
28 04 2023
28 04 2023
Historique:
medline:
1
5
2023
pubmed:
28
4
2023
entrez:
28
4
2023
Statut:
ppublish
Résumé
Granzyme A from killer lymphocytes cleaves gasdermin B (GSDMB) and triggers pyroptosis in targeted human tumor cells, eliciting antitumor immunity. However, GSDMB has a controversial role in pyroptosis and has been linked to both anti- and protumor functions. Here, we found that
Identifiants
pubmed: 37115914
doi: 10.1126/sciimmunol.adg3196
pmc: PMC10338320
mid: NIHMS1914945
doi:
Substances chimiques
Protein Isoforms
0
Types de publication
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
eadg3196Subventions
Organisme : NCI NIH HHS
ID : P30 CA016672
Pays : United States
Organisme : Howard Hughes Medical Institute
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA240955
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI139914
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM133658
Pays : United States
Organisme : NIBIB NIH HHS
ID : R01 EB030015
Pays : United States
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