Effects of the probiotic
Lactiplantibacillus plantarum IMC 510®
clinical trial
gut microbiota
obesity
probiotic supplementation
Journal
Frontiers in nutrition
ISSN: 2296-861X
Titre abrégé: Front Nutr
Pays: Switzerland
ID NLM: 101642264
Informations de publication
Date de publication:
2023
2023
Historique:
received:
11
01
2023
accepted:
23
03
2023
medline:
1
5
2023
pubmed:
1
5
2023
entrez:
1
5
2023
Statut:
epublish
Résumé
In recent decades, obesity prevalence has reached epidemic proportions and considering the pivotal role of gut microbiota (GM) in the regulation of energy balance, alternative non-pharmacological approaches involving probiotics' administration have been proposed. The aim of the present study was to evaluate the effect of Forty overweight/obese subjects were randomly assigned to daily consume the probiotic Compared to placebo, probiotic supplementation determined a significant decrease in body weight, BMI, waist circumference, waist-to-height ratio, and blood glucose. Moreover, probiotic administration produced a significant decrease of the genera Thanks to its effect in increasing some beneficial gut bacteria and lowering effects on waist circumference, fasting glucose levels and gastrointestinal symptoms of obese subjects,
Sections du résumé
Background and aim
UNASSIGNED
In recent decades, obesity prevalence has reached epidemic proportions and considering the pivotal role of gut microbiota (GM) in the regulation of energy balance, alternative non-pharmacological approaches involving probiotics' administration have been proposed. The aim of the present study was to evaluate the effect of
Methods
UNASSIGNED
Forty overweight/obese subjects were randomly assigned to daily consume the probiotic
Results
UNASSIGNED
Compared to placebo, probiotic supplementation determined a significant decrease in body weight, BMI, waist circumference, waist-to-height ratio, and blood glucose. Moreover, probiotic administration produced a significant decrease of the genera
Conclusion
UNASSIGNED
Thanks to its effect in increasing some beneficial gut bacteria and lowering effects on waist circumference, fasting glucose levels and gastrointestinal symptoms of obese subjects,
Identifiants
pubmed: 37125045
doi: 10.3389/fnut.2023.1142527
pmc: PMC10130646
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1142527Informations de copyright
Copyright © 2023 Pagliai, Coman, Baldi, Dinu, Nannini, Russo, Curini, Colombini, Lotti, Pallecchi, Di Gloria, Bartolucci, Ramazzotti, Verdenelli, Sofi and Amedei.
Déclaration de conflit d'intérêts
MMC and MCV were employed by Synbiotec S.r.l. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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