Evaluation of the Quality of Codonopsis Radix in Different Growth Years by the AHP-CRITIC Method.


Journal

Chemistry & biodiversity
ISSN: 1612-1880
Titre abrégé: Chem Biodivers
Pays: Switzerland
ID NLM: 101197449

Informations de publication

Date de publication:
Jun 2023
Historique:
received: 26 11 2022
accepted: 27 04 2023
medline: 26 6 2023
pubmed: 2 5 2023
entrez: 1 5 2023
Statut: ppublish

Résumé

The quality of traditional Chinese medicines (TCM) has a significant correlation with the source and growth years. However, there is no research on the relationship between the growth period and the quality of Codonopsis Radix (CR). This work aims to evaluate the quality of CR in different growth years (2-5 years). First, the content of 6 efficacy-related and 28 nutrient-related components in different growth years of CR was analyzed. The results showed that with the increase in growth years of CR, the content of some components increased, while some decreased. Then, the AHP-CRITIC method was performed to score the CR in different growth years, the results showed that the comprehensive score of CR increased with the increase of growth years, and the 5-year-CR had the highest score. Finally, in vitro activity assays were designed to verify the evaluation results. The results demonstrated that with the increase of growth years, the spleen lymphocyte proliferation activity and DPPH free radical scavenging activity of CR were enhanced, which proved that the AHP-CRITIC method is reasonable to evaluate the quality of CR in different growth years. The aforementioned findings demonstrated that CR quality improved with longer planting years.

Identifiants

pubmed: 37127546
doi: 10.1002/cbdv.202201108
doi:

Substances chimiques

Drugs, Chinese Herbal 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e202201108

Subventions

Organisme : major science and technology project of Gansu Province
ID : 21ZD4FA013
Organisme : People's Livelihood Special Project from Technical Innovation Guide Plan of Gansu Province
ID : 20CX4FK014
Organisme : Special Project of Science and Technology Commissioner of Gansu Province
ID : 22CX8GA009
Organisme : Talent Innovation and Entrepreneurship Project of Lanzhou
ID : 2017-RC-115
Organisme : Talent Innovation and Entrepreneurship Project of Lanzhou
ID : 2020-RC-41

Informations de copyright

© 2023 Wiley-VHCA AG, Zurich, Switzerland.

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Auteurs

Yanping Wang (Y)

School of Pharmacy, State Key Laboratory of Functional Organic Molecular Chemistry, Institute of Codonopsis Radix, Lanzhou University, 199 Dong-gang Road West, Lanzhou, 730000, P. R. China.

Zixia Wang (Z)

School of Pharmacy, State Key Laboratory of Functional Organic Molecular Chemistry, Institute of Codonopsis Radix, Lanzhou University, 199 Dong-gang Road West, Lanzhou, 730000, P. R. China.

Jingjing Zhang (J)

School of Pharmacy, State Key Laboratory of Functional Organic Molecular Chemistry, Institute of Codonopsis Radix, Lanzhou University, 199 Dong-gang Road West, Lanzhou, 730000, P. R. China.

Huaqiao Yu (H)

School of Pharmacy, State Key Laboratory of Functional Organic Molecular Chemistry, Institute of Codonopsis Radix, Lanzhou University, 199 Dong-gang Road West, Lanzhou, 730000, P. R. China.

Yan Chen (Y)

School of Pharmacy, State Key Laboratory of Functional Organic Molecular Chemistry, Institute of Codonopsis Radix, Lanzhou University, 199 Dong-gang Road West, Lanzhou, 730000, P. R. China.

Yingrui Gao (Y)

School of Pharmacy, State Key Laboratory of Functional Organic Molecular Chemistry, Institute of Codonopsis Radix, Lanzhou University, 199 Dong-gang Road West, Lanzhou, 730000, P. R. China.

Xiaodong Li (X)

Codonopsis Radix Research Institute, Gansu Province, Lanzhou, Gansu, 730000, P. R. China.

Wen Li (W)

School of Pharmacy, State Key Laboratory of Functional Organic Molecular Chemistry, Institute of Codonopsis Radix, Lanzhou University, 199 Dong-gang Road West, Lanzhou, 730000, P. R. China.
Codonopsis Radix Research Institute, Gansu Province, Lanzhou, Gansu, 730000, P. R. China.
Codonopsis Radix Industrial Technology Engineering Research Center, Gansu Province, Lanzhou, Gansu, 730000, P. R. China.

Fangdi Hu (F)

School of Pharmacy, State Key Laboratory of Functional Organic Molecular Chemistry, Institute of Codonopsis Radix, Lanzhou University, 199 Dong-gang Road West, Lanzhou, 730000, P. R. China.
Codonopsis Radix Research Institute, Gansu Province, Lanzhou, Gansu, 730000, P. R. China.
Codonopsis Radix Industrial Technology Engineering Research Center, Gansu Province, Lanzhou, Gansu, 730000, P. R. China.

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