Lutein-loaded chitosan/alginate-coated Fe

Alginate Box-Behnken design Breast cancer Chitosan Lutein Magnetic nanoparticles

Journal

International journal of biological macromolecules
ISSN: 1879-0003
Titre abrégé: Int J Biol Macromol
Pays: Netherlands
ID NLM: 7909578

Informations de publication

Date de publication:
01 Jul 2023
Historique:
received: 10 01 2023
revised: 07 03 2023
accepted: 26 04 2023
medline: 19 6 2023
pubmed: 4 5 2023
entrez: 3 5 2023
Statut: ppublish

Résumé

Magnetic drug targeting can be a strategy for effectively delivering phytochemicals in cancer treatment. Here, we demonstrate the benefit of magnetic targeting with superparamagnetic iron oxide nanoparticles for cytotoxicity enhancement of lutein (LUT) against breast cancer cells. Fabrication of LUT-loaded chitosan/alginate iron oxide nanoparticles (LUT-CS/Alg-Fe

Identifiants

pubmed: 37137353
pii: S0141-8130(23)01567-2
doi: 10.1016/j.ijbiomac.2023.124673
pii:
doi:

Substances chimiques

Alginates 0
Lutein X72A60C9MT
Chitosan 9012-76-4

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

124673

Informations de copyright

Copyright © 2023 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Bryan Paul Bulatao (BP)

Center of Excellence in Natural Products for Ageing and Chronic Diseases, Chulalongkorn University, Bangkok 10330, Thailand; Pharmaceutical Sciences and Technology Program, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand. Electronic address: bibulatao@up.edu.ph.

Nonthaneth Nalinratana (N)

Center of Excellence in Natural Products for Ageing and Chronic Diseases, Chulalongkorn University, Bangkok 10330, Thailand; Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand. Electronic address: nonthaneth.n@chula.ac.th.

Pongsakorn Jantaratana (P)

Department of Physics, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand. Electronic address: fscipsj@ku.ac.th.

Opa Vajragupta (O)

Center of Excellence in Natural Products for Ageing and Chronic Diseases, Chulalongkorn University, Bangkok 10330, Thailand; Molecular Probes for Imaging Research Network, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand. Electronic address: opa.v@chula.ac.th.

Pranee Rojsitthisak (P)

Center of Excellence in Natural Products for Ageing and Chronic Diseases, Chulalongkorn University, Bangkok 10330, Thailand; Metallurgy and Materials Science Research Institute, Chulalongkorn University, Bangkok 10330, Thailand. Electronic address: pranee.l@chula.ac.th.

Pornchai Rojsitthisak (P)

Center of Excellence in Natural Products for Ageing and Chronic Diseases, Chulalongkorn University, Bangkok 10330, Thailand; Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand. Electronic address: pornchai.r@chula.ac.th.

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Classifications MeSH