Salivary Antioxidant Profile in Patients with Systemic Sclerosis and Periodontitis.


Journal

Mediators of inflammation
ISSN: 1466-1861
Titre abrégé: Mediators Inflamm
Pays: United States
ID NLM: 9209001

Informations de publication

Date de publication:
2023
Historique:
received: 21 09 2022
revised: 26 10 2022
accepted: 24 11 2022
medline: 5 5 2023
pubmed: 4 5 2023
entrez: 4 5 2023
Statut: epublish

Résumé

The aim of the present study was to compare periodontal status and antioxidant profile in unstimulated saliva of systemic sclerosis (SSc) patients with periodontitis and systemically healthy periodontitis patients. Twenty patients with established diagnoses of systemic sclerosis and periodontitis (SSc group) and 20 systemically healthy individuals with periodontitis (P group) were enrolled in the study. Clinical periodontal parameters (clinical attachment level (CAL), gingival recession (GR), periodontal probing depth (PPD), and gingival index (GI)) and concentration of uric acid (UA), superoxide dismutase (SOD), and glutathione peroxidase (GPX) in unstimulated saliva samples were assessed. There were significantly higher mean values of CAL (4.8 ± 0.21 mm versus 3.18 ± 0.17 mm; The results may indicate higher periodontal destruction and antioxidant perturbations in unstimulated saliva of SSc patients with periodontitis compared to systemically healthy periodontitis patients.

Identifiants

pubmed: 37138665
doi: 10.1155/2023/7886272
pmc: PMC10151151
doi:

Substances chimiques

Superoxide Dismutase EC 1.15.1.1
Uric Acid 268B43MJ25
Oxidoreductases EC 1.-

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

7886272

Informations de copyright

Copyright © 2023 Stefan I. Sredojevic et al.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Stefan I Sredojevic (SI)

Department of Periodontology, School of Dental Medicine, University of Belgrade, Dr Subotica 4, Belgrade, Serbia.

Slavica Pavlov Dolijanovic (SP)

Institute of Rheumatology, School of Medicine, University of Belgrade, Resavska 69, Belgrade, Serbia.

Ivan Dozic (I)

General and Oral Biochemistry, School of Dental Medicine, University of Belgrade, Dr Subotica 4, Belgrade, Serbia.

Jovana Kuzmanovic Pficer (JK)

Biomedical Statistics and Informatics, School of Dental Medicine, University of Belgrade, Dr Subotica 4, Belgrade, Serbia.

Zoran Aleksic (Z)

Department of Periodontology, School of Dental Medicine, University of Belgrade, Dr Subotica 4, Belgrade, Serbia.

Natasa S Nikolic-Jakoba (NS)

Department of Periodontology, School of Dental Medicine, University of Belgrade, Dr Subotica 4, Belgrade, Serbia.

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