Convergence of scaffold-guided bone regeneration principles and microvascular tissue transfer surgery.


Journal

Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440

Informations de publication

Date de publication:
05 05 2023
Historique:
medline: 8 5 2023
pubmed: 5 5 2023
entrez: 5 5 2023
Statut: ppublish

Résumé

A preclinical evaluation using a regenerative medicine methodology comprising an additively manufactured medical-grade ε-polycaprolactone β-tricalcium phosphate (mPCL-TCP) scaffold with a corticoperiosteal flap was undertaken in eight sheep with a tibial critical-size segmental bone defect (9.5 cm

Identifiants

pubmed: 37146134
doi: 10.1126/sciadv.add6071
pmc: PMC10162672
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eadd6071

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Auteurs

David S Sparks (DS)

Centre for Biomedical Technologies, School of Mechanical, Medical, and Process Engineering, Faculty of Engineering, Queensland University of Technology, Brisbane, QLD, Australia.
Department of Plastic and Reconstructive Surgery, Princess Alexandra Hospital, Woolloongabba, QLD, Australia.
Southside Clinical Division, School of Medicine, University of Queensland, Woolloongabba, QLD, Australia.

Flavia M Savi (FM)

Centre for Biomedical Technologies, School of Mechanical, Medical, and Process Engineering, Faculty of Engineering, Queensland University of Technology, Brisbane, QLD, Australia.
ARC Training Centre for Multiscale 3D Imaging, Modelling, and Manufacturing, Queensland University of Technology, Brisbane, QLD, Australia.

Constantin E Dlaska (CE)

Centre for Biomedical Technologies, School of Mechanical, Medical, and Process Engineering, Faculty of Engineering, Queensland University of Technology, Brisbane, QLD, Australia.

Siamak Saifzadeh (S)

Centre for Biomedical Technologies, School of Mechanical, Medical, and Process Engineering, Faculty of Engineering, Queensland University of Technology, Brisbane, QLD, Australia.
ARC Training Centre for Multiscale 3D Imaging, Modelling, and Manufacturing, Queensland University of Technology, Brisbane, QLD, Australia.
Medical Engineering Research Facility, Queensland University of Technology, Chermside, QLD, Australia.

Gary Brierly (G)

Centre for Biomedical Technologies, School of Mechanical, Medical, and Process Engineering, Faculty of Engineering, Queensland University of Technology, Brisbane, QLD, Australia.

Edward Ren (E)

Centre for Biomedical Technologies, School of Mechanical, Medical, and Process Engineering, Faculty of Engineering, Queensland University of Technology, Brisbane, QLD, Australia.

Amaia Cipitria (A)

Department of Biomaterials, Max Planck Institute of Colloids and Interfaces, Potsdam, Germany.
Biodonostia Health Research Institute, San Sebastian, Spain.
IKERBASQUE, Basque Foundation for Science, Bilbao, Spain.

Johannes C Reichert (JC)

Department of Orthopaedics and Orthopaedic Surgery, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, Greifswald, Germany.

Marie-Luise Wille (ML)

Centre for Biomedical Technologies, School of Mechanical, Medical, and Process Engineering, Faculty of Engineering, Queensland University of Technology, Brisbane, QLD, Australia.
ARC Training Centre for Multiscale 3D Imaging, Modelling, and Manufacturing, Queensland University of Technology, Brisbane, QLD, Australia.

Michael A Schuetz (MA)

Centre for Biomedical Technologies, School of Mechanical, Medical, and Process Engineering, Faculty of Engineering, Queensland University of Technology, Brisbane, QLD, Australia.
ARC Training Centre for Multiscale 3D Imaging, Modelling, and Manufacturing, Queensland University of Technology, Brisbane, QLD, Australia.
Jamieson Trauma Institute, Royal Brisbane Hospital, Herston, QLD, Australia.

Nicola Ward (N)

Department of Orthopaedics, Princess Alexandra Hospital, Woolloongabba, QLD, Australia.

Michael Wagels (M)

Department of Plastic and Reconstructive Surgery, Princess Alexandra Hospital, Woolloongabba, QLD, Australia.
Southside Clinical Division, School of Medicine, University of Queensland, Woolloongabba, QLD, Australia.
Australian Centre for Complex Integrated Surgical Solutions (ACCISS), Princess Alexandra Hospital, Woolloongabba, QLD, Australia.

Dietmar W Hutmacher (DW)

Centre for Biomedical Technologies, School of Mechanical, Medical, and Process Engineering, Faculty of Engineering, Queensland University of Technology, Brisbane, QLD, Australia.
ARC Training Centre for Multiscale 3D Imaging, Modelling, and Manufacturing, Queensland University of Technology, Brisbane, QLD, Australia.
ARC Training Centre for Additive Biomanufacturing, Queensland University of Technology, Kelvin Grove, QLD, Australia.

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Classifications MeSH