A high fat diet fosters elevated bisretinoids.

Animals Mice Diet, High-Fat / adverse effects Leptin / genetics Mice, Inbred C57BL Mice, Obese Obesity / metabolism Retinol-Binding Proteins / metabolism Vitamin A / metabolism Photoreceptor Cells / cytology Cell Survival Retinoids / metabolism
diet-induced obesity phosphatidylethanolamine retina retinol-binding protein 4 vitamin A

Journal

The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R

Informations de publication

Date de publication:
06 2023
Historique:
received: 26 01 2023
revised: 28 04 2023
accepted: 29 04 2023
medline: 28 6 2023
pubmed: 6 5 2023
entrez: 5 5 2023
Statut: ppublish

Résumé

High dietary fat intake is associated with metabolic dysregulation, but little is known regarding the effects of a high fat diet (HFD) on photoreceptor cell functioning. We explored the intersection of an HFD and the visual cycle adducts that form in photoreceptor cells by nonenzymatic reactions. In black C57BL/6J mice and albino C57BL/6J

Identifiants

DOI: 10.1016/j.jbc.2023.104784 PMID: 37146972 PMC: PMC10236470
pubmed: 37146972
pii: S0021-9258(23)01812-4
doi: 10.1016/j.jbc.2023.104784
pmc: PMC10236470
pii:
doi:

Substances chimiques

Leptin 0
Retinol-Binding Proteins 0
Vitamin A 11103-57-4
Rbp4 protein, mouse 0
Retinoids 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

104784

Subventions

Organisme : NEI NIH HHS
ID : P30 EY019007
Pays : United States
Organisme : NEI NIH HHS
ID : R01 EY012951
Pays : United States
Organisme : NIH HHS
ID : S10 OD028637
Pays : United States

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflicts of interest The authors declare that there are no conflicts of interest related to the contents of this article.

Auteurs

Hye Jin Kim (HJ)

Departments of Ophthalmology, Columbia University Medical Center, New York New York, USA.

Jin Zhao (J)

Departments of Ophthalmology, Columbia University Medical Center, New York New York, USA.

Jose L Walewski (JL)

Departments of Medicine, Columbia University Medical Center, New York New York, USA.

Janet R Sparrow (JR)

Departments of Ophthalmology, Columbia University Medical Center, New York New York, USA; Departments of Pathology and Cell Biology, Columbia University Medical Center, New York New York, USA. Electronic address: jrs88@columbia.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › A high fat diet fosters elevated bisretinoids.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › A high fat diet fosters elevated bisretinoids.
questionsmedicales.fr › Phénomènes physiologiques › Alimentation et nutrition › Phénomènes physiologiques nutritionnels › Régime alimentaire › Alimentation riche en graisse › A high fat diet fosters elevated bisretinoids.
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Adipokines › Leptine › A high fat diet fosters elevated bisretinoids.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › A high fat diet fosters elevated bisretinoids.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souches mutantes de souris › Souris obèse › A high fat diet fosters elevated bisretinoids.
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Obésité › A high fat diet fosters elevated bisretinoids.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de transport › Protéines de liaison au rétinol › A high fat diet fosters elevated bisretinoids.
questionsmedicales.fr › Facteurs biologiques › Pigments biologiques › Caroténoïdes › Rétinoïdes › Rétinol › A high fat diet fosters elevated bisretinoids.
questionsmedicales.fr › Cellules › Neurones › Neurones afférents › Cellules réceptrices sensorielles › Cellules photoréceptrices › A high fat diet fosters elevated bisretinoids.
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Survie cellulaire › A high fat diet fosters elevated bisretinoids.
questionsmedicales.fr › Facteurs biologiques › Pigments biologiques › Caroténoïdes › Rétinoïdes › A high fat diet fosters elevated bisretinoids.