The role of comprehensive two-dimensional gas chromatography in mineral oil determination.

Comprehensive two-dimensional gas chromatography (GC × GC) Food Hyphenated chromatographic techniques Mineral oil aromatic hydrocarbons (MOAH) Mineral oil saturated hydrocarbons (MOSH)

Journal

Analytical and bioanalytical chemistry

ISSN: 1618-2650

Titre abrégé: Anal Bioanal Chem

Pays: Germany

ID NLM: 101134327

Informations de publication

Date de publication:
Sep 2023

Historique:

received: 26 03 2023

accepted: 25 04 2023

revised: 24 04 2023

medline: 6 5 2023

pubmed: 6 5 2023

entrez: 5 5 2023

Statut: ppublish

Résumé

Mineral oil hydrocarbons (MOH) contain a wide structural diversity of molecules, for which the reference method of analysis is the online coupled liquid chromatography-gas chromatography with flame ionization detection (LC-GC-FID). These compounds are very heterogeneous from a toxicological viewpoint, and an accurate risk assessment when dealing with a MOH contamination can only be performed if sufficient information is available on the types of structures present (i.e., number of carbons, degree of alkylation, number of aromatic rings). Unfortunately, the separation performances of the current LC-GC-FID method are insufficient for such characterization, not even mentioning the possible coelution of interfering compounds which additionally hinder MOH determination. Comprehensive two-dimensional gas chromatography (GC × GC), while mostly used for confirmation purposes in the past, starts to prove its relevance for overcoming the weaknesses of the LC-GC method and reaching even better the analytical requirements defined in the latest EFSA opinion. The present paper therefore aims at highlighting how GC × GC has contributed to the understanding of the MOH topic, how it has developed to meet the requirements of MOH determination, and how it could play a role in the field for overcoming many of the current analytical and toxicological challenges related to the topic.

Identifiants

DOI: 10.1007/s00216-023-04718-3 PMID: 37147559

pubmed: 37147559

doi: 10.1007/s00216-023-04718-3

pii: 10.1007/s00216-023-04718-3

doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

Pagination

5067-5082

Subventions

Organisme : Fonds pour la Formation à la Recherche dans l'Industrie et dans l'Agriculture

ID : T.0187.23

Informations de copyright

Références

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