Post-discharge health assessment in survivors of coronavirus disease: a time-point analysis of a prospective cohort study.
Coronavirus
Covid-19
Psychiatric
Pulmonary function
Quality of life
SARS-CoV-2
Journal
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
ISSN: 1573-2649
Titre abrégé: Qual Life Res
Pays: Netherlands
ID NLM: 9210257
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
accepted:
30
03
2023
medline:
2
8
2023
pubmed:
7
5
2023
entrez:
7
5
2023
Statut:
ppublish
Résumé
The objective of this study was to quantitatively evaluate psychological and quality of life-related complications at three months following discharge in hospitalized coronavirus disease 2019 (COVID-19) patients during the pandemic in Iran. In this time-point analysis of prospective cohort study data, adult patients hospitalized with symptoms suggestive of COVID-19 were enrolled. Patients were stratified in analyses based on severity. The primary outcomes consisted of psychological problems and pulmonary function tests (PFTs) in the three months following discharge, with Health-related quality of life (HRQoL) as the secondary outcome. Exploratory predictors were determined for both primary and secondary outcomes. 283 out of 900 (30%) eligible patients were accessible for the follow-up assessment and included in the study. The mean age was 53.65 ± 13.43 years, with 68% experiencing a severe disease course. At the time of the final follow-up, participants still reported persistent symptoms, among which fatigue, shortness of breath, and cough were the most common. Based on the regression-adjusted analysis, lower levels of forced expiratory volume in one second (FEV1) to forced vital capacity (FVC) ratio was associated with higher levels of depression (standardized β = - 0.161 (SE = 0.042), P = 0.017) and stress levels (standardized β =- 0.110 (SE = 0.047), P = 0.015). Furthermore, higher levels of anti-SARS-CoV-2 immunoglobulin-M (IgM) were associated with significantly lower levels of depression (standardized β = - 0.139 (SE = 0.135), P = 0.031). There is an association between lung damage during COVID-19 and the reduction of pulmonary function for up to three months from acute infection in hospitalized patients. Varying degrees of anxiety, depression, stress, and low HRQoL frequently occur in patients with COVID-19. More severe lung damage and lower COVID-19 antibodies were associated with lower levels of psychological health.
Identifiants
pubmed: 37149817
doi: 10.1007/s11136-023-03415-z
pii: 10.1007/s11136-023-03415-z
pmc: PMC10163985
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2681-2693Subventions
Organisme : Isfahan University of Medical Sciences
ID : IR.MUI.MED.REC.1399.517
Informations de copyright
© 2023. The Author(s), under exclusive licence to Springer Nature Switzerland AG.
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