Updates on preimplantation embryo research.
Development
cell biology
cytoskeleton
Journal
Fertility and sterility
ISSN: 1556-5653
Titre abrégé: Fertil Steril
Pays: United States
ID NLM: 0372772
Informations de publication
Date de publication:
09 2023
09 2023
Historique:
received:
16
01
2023
revised:
27
04
2023
accepted:
28
04
2023
medline:
28
8
2023
pubmed:
8
5
2023
entrez:
7
5
2023
Statut:
ppublish
Résumé
Preimplantation development is the only stage of human development that can be studied outside the body in real time, as human embryos can be produced by in vitro fertilization and cultured in the laboratory as self-contained structures until the blastocyst stage. Here, we focus some of the key cellular and morphogenetic processes by which the 1-cell embryo is transformed gradually into a blastocyst ready for implantation. Although most of our knowledge about the dynamic series of events patterning preimplantation human development derives from work in mouse embryos, we discuss key differences that could exist with humans. Furthermore, we highlight how new approaches may enable to reveal many of the unknown processes driving human preimplantation development, particularly using noninvasive imaging and genetic technologies.
Identifiants
pubmed: 37150393
pii: S0015-0282(23)00336-9
doi: 10.1016/j.fertnstert.2023.04.039
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
467-472Informations de copyright
Copyright © 2023 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.