Resectability in bronchogenic carcinoma: A single‑center experience.
lobectomy
lung cancer
pneumonectomy
tumor resection
Journal
Oncology letters
ISSN: 1792-1082
Titre abrégé: Oncol Lett
Pays: Greece
ID NLM: 101531236
Informations de publication
Date de publication:
Jun 2023
Jun 2023
Historique:
received:
28
09
2022
accepted:
09
02
2023
medline:
8
5
2023
pubmed:
8
5
2023
entrez:
8
5
2023
Statut:
epublish
Résumé
Bronchogenic carcinoma comprises >90% of primary lung tumors. The present study aimed to estimate the profile of patients with bronchogenic carcinoma and assess the cancer resectability in newly diagnosed patients. This is a single-center retrospective review conducted over a period of 5 years. A total of 800 patients with bronchogenic carcinoma were included. The diagnoses were mostly proven with either cytological examination or histopathological diagnosis. Sputum analysis, cytological examination of pleural effusion and bronchoscopic examination were performed. Lymph node biopsy, minimally invasive procedures (mediastinoscopy and video-assisted thoracoscopic surgery), tru-cut biopsy or fine-needle aspiration was used to obtain the samples for diagnosis. The masses were removed by lobectomy and pneumonectomy. The age range was between 22 and 87 years, with a mean age of 62.95 years. Males represented the predominant sex. Most of the patients were smokers or ex-smokers. The most common symptom was a cough, followed by dyspnea. Chest radiography revealed abnormal findings in 699 patients. A bronchoscopic evaluation was performed for the majority of patients (n=633). Endobronchial masses and other suggestive malignancy findings were present in 473 patients (83.1%) of the 569 who underwent fiberoptic bronchoscopy. Cytological and/or histopathological samples of 581 patients (91.8%) were positive. Small cell lung cancer (SCLC) occurred in 38 patients (4.75%) and non-SCLC was detected in 762 patients (95.25%). Lobectomy was the main surgical procedure, followed by pneumonectomy. A total of 5 patients developed postoperative complications without any mortality. In conclusion, bronchogenic carcinoma is rapidly increasing without a predilection for sex in the Iraqi population. Advanced preoperative staging and investigation tools are required to determine the rate of resectability.
Identifiants
pubmed: 37153056
doi: 10.3892/ol.2023.13805
pii: OL-25-6-13805
pmc: PMC10157354
doi:
Types de publication
Journal Article
Langues
eng
Pagination
219Informations de copyright
Copyright: © Marie et al.
Déclaration de conflit d'intérêts
The authors declare that they have no competing interests.
Références
Chest. 2003 Jan;123(1 Suppl):115S-128S
pubmed: 12527571
JAMA. 1984 Jan 13;251(2):260-4
pubmed: 6361296
Am Fam Physician. 2007 Mar 1;75(5):683-8
pubmed: 17375514
Thorax. 2001 Sep;56 Suppl 2:ii38-44
pubmed: 11514705
Clin Chest Med. 1993 Mar;14(1):87-98
pubmed: 8462250
Thorax. 2006 Aug;61(8):710-5
pubmed: 16601091
CA Cancer J Clin. 2011 Mar-Apr;61(2):69-90
pubmed: 21296855
J Thorac Cardiovasc Surg. 2008 Feb;135(2):247-54
pubmed: 18242243
Ann Thorac Surg. 1988 Oct;46(4):472-4
pubmed: 3052336
J Bronchology Interv Pulmonol. 2018 Jul;25(3):239-244
pubmed: 27261933
Ann Surg Oncol. 2010 Jun;17(6):1471-4
pubmed: 20180029
J Thorac Cardiovasc Surg. 1993 Nov;106(5):868-74
pubmed: 8231209
Onkologie. 2001 Apr;24(2):151-4
pubmed: 11441295
Chest. 1980 Mar;77(3):337-42
pubmed: 7357934
Clin Chest Med. 2018 Mar;39(1):181-193
pubmed: 29433714
Eur Respir Rev. 2016 Jun;25(140):189-98
pubmed: 27246596
Eur Respir J. 1999 Aug;14(2):419-22
pubmed: 10515423
Lung Cancer. 2019 Aug;134:52-58
pubmed: 31319995