In-Class Cross-Reactivity among Hospitalized Patients with Hypersensitivity Reactions to Fluoroquinolones.


Journal

Antimicrobial agents and chemotherapy
ISSN: 1098-6596
Titre abrégé: Antimicrob Agents Chemother
Pays: United States
ID NLM: 0315061

Informations de publication

Date de publication:
15 06 2023
Historique:
medline: 19 6 2023
pubmed: 8 5 2023
entrez: 8 5 2023
Statut: ppublish

Résumé

Results from this large, multicenter study suggest that patients with a confirmed ciprofloxacin, moxifloxacin, or levofloxacin hypersensitivity reaction are likely to tolerate other fluoroquinolones. Avoiding different fluoroquinolones in patients labeled with a ciprofloxacin, moxifloxacin, or levofloxacin allergy may not always be mandatory. This was a study of patients with a ciprofloxacin, moxifloxacin, or levofloxacin hypersensitivity reaction and a documented electronic medical record administration of a different fluoroquinolone. Numerically, the most common reaction risk occurred with a challenge to moxifloxacin (2/19; 9.5%), followed by ciprofloxacin (6/89; 6.3%), and levofloxacin (1/44; 2.2%).

Identifiants

pubmed: 37154772
doi: 10.1128/aac.00374-23
pmc: PMC10269124
doi:

Substances chimiques

Fluoroquinolones 0
Moxifloxacin U188XYD42P
Levofloxacin 6GNT3Y5LMF
Anti-Bacterial Agents 0
Ciprofloxacin 5E8K9I0O4U
Quinolines 0
Aza Compounds 0
Ofloxacin A4P49JAZ9H

Types de publication

Multicenter Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0037423

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Références

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pubmed: 36026700

Auteurs

Sunish Shah (S)

Antimicrobial Management Program, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

Lloyd G Clarke (LG)

Antimicrobial Management Program, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

Kathleen K Adams (KK)

University of Connecticut School of Pharmacy, Storrs Mansfield, Connecticut, USA.

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Classifications MeSH