Polydopamine conjugated SiO

cytotoxicity drug transporters malignant melanoma polydopamine silicon oxide nanoparticles

Journal

Therapeutic delivery
ISSN: 2041-6008
Titre abrégé: Ther Deliv
Pays: England
ID NLM: 101538870

Informations de publication

Date de publication:
02 2023
Historique:
medline: 12 5 2023
pubmed: 9 5 2023
entrez: 9 5 2023
Statut: ppublish

Résumé

Silica nanoparticles (SiO Tiny particles can be small enough to enter cells. This is why they may be useful in the treatment of cancer. We made particles in a way that is friendly for human cells, then we analyzed their effects on cancer cells. Our tests showed that these particles could be useful for treatment because they do not worsen cancer cells. This is important because sometimes after treatment, cancer cells can become more dangerous. This way, even if the drug did not work, the cancer will not worsen.

Autres résumés

Type: plain-language-summary (eng)
Tiny particles can be small enough to enter cells. This is why they may be useful in the treatment of cancer. We made particles in a way that is friendly for human cells, then we analyzed their effects on cancer cells. Our tests showed that these particles could be useful for treatment because they do not worsen cancer cells. This is important because sometimes after treatment, cancer cells can become more dangerous. This way, even if the drug did not work, the cancer will not worsen.

Identifiants

pubmed: 37158273
doi: 10.4155/tde-2023-0010
doi:

Substances chimiques

polydopamine 0
Drug Carriers 0
Silicon Dioxide 7631-86-9

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

157-173

Auteurs

Ioana Mădălina Buhazi (IM)

Electron Microscopy Center "C. Crăciun", Biology & Geology Faculty, Babeș-Bolyai University, Cluj-Napoca, 5-7 Clinicilor str., 400006, Romania.

Ioana-Georgeta Grosu (IG)

Molecular & Biomolecular Physics Department, National Institute for R&D for Isotopic & Molecular Technologies (INCDTIM), Cluj-Napoca, 67-103 Donath str., 400293, Romania.

Xenia Filip (X)

Molecular & Biomolecular Physics Department, National Institute for R&D for Isotopic & Molecular Technologies (INCDTIM), Cluj-Napoca, 67-103 Donath str., 400293, Romania.

Anca Petran (A)

Physics of Nanostructured Systems, National Institute for R&D for Isotopic & Molecular Technologies (INCDTIM), Cluj-Napoca, 67-103 Donath str., 400293, Romania.

Septimiu Cassian Tripon (SC)

Electron Microscopy Center "C. Crăciun", Biology & Geology Faculty, Babeș-Bolyai University, Cluj-Napoca, 5-7 Clinicilor str., 400006, Romania.
LIME-CETATEA, National Institute for R&D for Isotopic & Molecular Technologies (INCDTIM), Cluj-Napoca, 67-103 Donath str., 400293, Romania.

Călin Gabriel Floare (CG)

Molecular & Biomolecular Physics Department, National Institute for R&D for Isotopic & Molecular Technologies (INCDTIM), Cluj-Napoca, 67-103 Donath str., 400293, Romania.

Maria Suciu (M)

Electron Microscopy Center "C. Crăciun", Biology & Geology Faculty, Babeș-Bolyai University, Cluj-Napoca, 5-7 Clinicilor str., 400006, Romania.
LIME-CETATEA, National Institute for R&D for Isotopic & Molecular Technologies (INCDTIM), Cluj-Napoca, 67-103 Donath str., 400293, Romania.

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Classifications MeSH