Light-Driven Photoconversion of Squaramides with Implications in Anion Transport.


Journal

Organic letters
ISSN: 1523-7052
Titre abrégé: Org Lett
Pays: United States
ID NLM: 100890393

Informations de publication

Date de publication:
19 May 2023
Historique:
medline: 9 5 2023
pubmed: 9 5 2023
entrez: 9 5 2023
Statut: ppublish

Résumé

Simple, clean and fast photoconversion of aniline-derived squaramides was achieved by flashlight illumination. UV irradiation enabled the photochemical squaramide ring-opening to generate 1,2-bisketenes, which DMSO trapped as the nucleophilic oxidant. The only photoproducts isolated were 3,4-arylamino maleic anhydrides, which present conformational preferences very different from those of their parent squaramides. Similar photoconversion was achieved in MeOH. The UV-mediated time-dependent anion transport inhibition was demonstrated, establishing a new approach for modulating the transport abilities of AD-squaramides.

Identifiants

pubmed: 37158572
doi: 10.1021/acs.orglett.3c00993
pmc: PMC10204084
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3423-3428

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Auteurs

Manel Vega (M)

Department of Chemistry, Universitat de les Illes Balears, Palma 07122, Spain.

Luis Martínez-Crespo (L)

Department of Chemistry, Universitat de les Illes Balears, Palma 07122, Spain.

Miguel Barceló-Oliver (M)

Department of Chemistry, Universitat de les Illes Balears, Palma 07122, Spain.

Carmen Rotger (C)

Department of Chemistry, Universitat de les Illes Balears, Palma 07122, Spain.

Antonio Costa (A)

Department of Chemistry, Universitat de les Illes Balears, Palma 07122, Spain.

Classifications MeSH