Climacturia: what treatment options do we offer to those with and without concomitant erectile dysfunction?


Journal

International journal of impotence research
ISSN: 1476-5489
Titre abrégé: Int J Impot Res
Pays: England
ID NLM: 9007383

Informations de publication

Date de publication:
Nov 2023
Historique:
received: 30 11 2022
accepted: 26 04 2023
revised: 18 04 2023
medline: 6 11 2023
pubmed: 10 5 2023
entrez: 10 5 2023
Statut: ppublish

Résumé

Radical prostatectomy for prostate cancer carries many sequelae, including climacturia, which is not commonly discussed and often under-recognized. To better understand treatment options for incontinence and climacturia, as well as those at time of penile implantation surgery, we completed a comprehensive literature review to identify nonoperative and operative treatments for patients with climacturia alone and those with concomitant climacturia and erectile dysfunction. Nonoperative interventions include behavioral modifications, physical therapy, and tension loops. Operative interventions include the artificial urinary sphincter, male urethral slings, Mini-Jupette sling, and a periurethral prosthesis. We also explore options that can be offered to patients who are also in need of penile prosthesis for concomitant erectile dysfunction. Contemporary work suggests that synchronous implantation of certain devices to treat both climacturia and erectile dysfunction can be done with proven safety and efficacy.

Identifiants

pubmed: 37161059
doi: 10.1038/s41443-023-00714-4
pii: 10.1038/s41443-023-00714-4
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

634-638

Informations de copyright

© 2023. The Author(s), under exclusive licence to Springer Nature Limited.

Références

Rawla P. Epidemiology of prostate cancer. World J Oncol. 2019;10:63–89.
pubmed: 31068988 pmcid: 6497009 doi: 10.14740/wjon1191
Schaeffer EM, Srinivas S, Adra N, An Y, Barocas D, Bitting R, et al. NCCN guidelines® insights: prostate cancer, version 1.2023: featured updates to the NCCN guidelines. J Natl Compr Cancer Netw. 2022;20:1288–98.
Bill-Axelson A, Holmberg L, Ruutu M, Häggman M, Andersson SO, Bratell S, et al. Radical prostatectomy versus watchful waiting in early prostate cancer. N Engl J Med. 2005;352:1977–84.
pubmed: 15888698 doi: 10.1056/NEJMoa043739
Christine B, Bella AJ. MP48-04 climacturia: an under-addressed sequela of radical prostatectomy, but treatment is only a sling away. J Urol. 2016;195:e636.
doi: 10.1016/j.juro.2016.02.344
El-Khatib FM, Towe M, Choi J, Yafi FA. Management of climacturia during inflatable penile prosthesis surgery. Curr Urol Rep. 2019;20:16.
pubmed: 30806828 doi: 10.1007/s11934-019-0879-3
Powers SA, Odom MR, Pak ES, Moomaw MA, Ashcraft KA, Koontz BF, et al. Prostate-confined radiation decreased pelvic ganglia neuronal survival and outgrowth. J Sex Med. 2019;16:27–41.
pubmed: 30621923 doi: 10.1016/j.jsxm.2018.11.010
O’Neil Brock B, Presson A, Gannon J, Stephenson Robert A, Lowrance W, Dechet Christopher B, et al. Climacturia after definitive treatment of prostate cancer. J Urol. 2014;191:159–63.
pubmed: 24050893 doi: 10.1016/j.juro.2013.06.122
Choi Judy M, Nelson Christian J, Stasi J, Mulhall JP. Orgasm associated incontinence (climacturia) following radical pelvic surgery: rates of occurrence and predictors. J Urol. 2007;177:2223–6.
pubmed: 17509325 doi: 10.1016/j.juro.2007.01.150
Mulhall JP. Penile length changes after radical prostatectomy. BJU Int. 2005;96:472–4.
pubmed: 16104892 doi: 10.1111/j.1464-410X.2005.05666.x
Barnas JL, Pierpaoli S, Ladd P, Valenzuela R, Aviv N, Parker M, et al. The prevalence and nature of orgasmic dysfunction after radical prostatectomy. BJU Int. 2004;94:603–5.
pubmed: 15329121 doi: 10.1111/j.1464-410X.2004.05009.x
Barnas J, Parker M, Guhring P, Mulhall JP. The utility of tamsulosin in the management of orgasm-associated pain: a pilot analysis. Eur Urol. 2005;47:361–5.
pubmed: 15716202 doi: 10.1016/j.eururo.2004.10.020
Nilsson AE, Carlsson S, Johansson E, Jonsson MN, Adding C, Nyberg T. et al. Orgasm-associated urinary incontinence and sexual life after radical prostatectomy. J Sex Med. 2011;8:2632–9.
pubmed: 21699660 doi: 10.1111/j.1743-6109.2011.02347.x
Lee J, Hersey K, Lee Charlotte T, Fleshner N. Climacturia following radical prostatectomy: prevalence and risk factors. J Urol. 2006;176:2562–5.
pubmed: 17085160 doi: 10.1016/j.juro.2006.07.158
Fode M, Serefoglu EC, Albersen M, Sønksen J. Sexuality following radical prostatectomy: is restoration of erectile function enough? Sex Med Rev. 2017;5:110–9.
pubmed: 27566909 doi: 10.1016/j.sxmr.2016.07.005
Geraerts I, Van Poppel H, Devoogdt N, De Groef A, Fieuws S, Van Kampen M. Pelvic floor muscle training for erectile dysfunction and climacturia 1 year after nerve sparing radical prostatectomy: a randomized controlled trial. Int J Impot Res. 2016;28:9–13.
pubmed: 26538105 doi: 10.1038/ijir.2015.24
Sighinolfi MC, Rivalta M, Mofferdin A, Micali S, De Stefani S, Bianchi G. Potential effectiveness of pelvic floor rehabilitation treatment for postradical prostatectomy incontinence, climacturia, and erectile dysfunction: a case series. J Sex Med. 2009;6:3496–9.
pubmed: 20092471 doi: 10.1111/j.1743-6109.2009.01493.x
Mehta A, Deveci S, Mulhall JP. Efficacy of a penile variable tension loop for improving climacturia after radical prostatectomy. BJU Int. 2013;111:500–4.
pubmed: 22672308 doi: 10.1111/j.1464-410X.2012.11269.x
Lai HH, Hsu EI, Teh BS, Butler EB, Boone TB. 13 years of experience with artificial urinary sphincter implantation at Baylor College of Medicine. J Urol. 2007;177:1021–5.
pubmed: 17296403 doi: 10.1016/j.juro.2006.10.062
Ostrowski I, Blewniewski M, Neugart F, von Heyden B, Selvaggio O, Iori F, et al. Multicentre experience with ZSI 375 artificial urinary sphincter for the treatment of stress urinary incontinence in men. Urologia 2017;84:148–52.
pubmed: 28574143 doi: 10.5301/uj.5000246
Jain R, Mitchell S, Laze J, Lepor H. The effect of surgical intervention for stress urinary incontinence (UI) on post‐prostatectomy UI during sexual activity. BJU Int. 2012;109:1208–12.
pubmed: 21895932 doi: 10.1111/j.1464-410X.2011.10506.x
Rolle L, Ceruti C, Sedigh O, Timpano M, Destefanis P, Lillaz B, et al. Surgical implantation of artificial urinary device and penile prosthesis through trans-scrotal incision for postprostatectomy urinary incontinence and erectile dysfunction: synchronous or delayed procedure? Urology. 2012;80:1046–50.
pubmed: 22999451 doi: 10.1016/j.urology.2012.08.003
Segal RL, Cabrini MR, Harris ED, Mostwin JL, Bivalacqua TJ, Burnett AL. Combined inflatable penile prosthesis-artificial urinary sphincter implantation: no increased risk of adverse events compared to single or staged device implantation. J Urol. 2013;190:2183–8.
pubmed: 23831315 doi: 10.1016/j.juro.2013.06.084
Patel N, Golan R, Halpern Joshua A, Sun T, Asafu-Adjei AD, Chughtai B, et al. A contemporary analysis of dual inflatable penile prosthesis and artificial urinary sphincter outcomes. J Urol. 2019;201:141–6.
pubmed: 30059687 doi: 10.1016/j.juro.2018.07.046
Comiter CV, Dobberfuhl AD. The artificial urinary sphincter and male sling for postprostatectomy incontinence: Which patient should get which procedure? Investig Clin Urol. 2016;57:3–13.
pubmed: 26966721 pmcid: 4778750 doi: 10.4111/icu.2016.57.1.3
Christine B, Wilson Steven K, Shamloul R, Bella Anthony J. Simultaneous placement of an inflatable penile prosthesis and AdVance male sling for erectile dysfunction and incontinence: Robust efficacy and safety data at 2 year follow-up. J Urol. 2010;183:e490.
doi: 10.1016/j.juro.2010.02.823
Yafi FA, Andrianne R, Alzweri L, Brady J, Butcher M, Chevalier D, et al. Andrianne mini-jupette graft at the time of inflatable penile prosthesis placement for the management of post-prostatectomy climacturia and minimal urinary incontinence. J Sex Med. 2018;15:789–96.
pubmed: 29523479 doi: 10.1016/j.jsxm.2018.01.015
Brady J, Choi E, Foley B, Wilson S, Yafi F. Using mini-jupette slings to treat post radical prostatectomy urinary incontinence: Foreplay incontinence, climacturia, and stress incontinence. J Sex Med. 2022;19:S208–9.
doi: 10.1016/j.jsxm.2022.03.474
Torrey R, Rajeshuni N, Ruel N, Muldrew S, Chan K. Radiation history affects continence outcomes after advance transobturator sling placement in patients with post-prostatectomy incontinence. Urology. 2013;82:713–7.
pubmed: 23831073 doi: 10.1016/j.urology.2013.03.075
Castle Erik P, Andrews Paul E, Itano N, Novicki Donald E, Swanson Scott K, Ferrigni Robert G. The male sling for post-prostatectomy incontinence: mean followup of 18 months. J Urol. 2005;173:1657–60.
pubmed: 15821530 doi: 10.1097/01.ju.0000154782.86431.41
Guimarães M, Oliveira R, Pinto R, Soares A, Maia E, Botelho F, et al. Intermediate-term results, up to 4 years, of a bone-anchored male perineal sling for treating male stress urinary incontinence after prostate surgery. BJU Int. 2009;103:500–4.
pubmed: 18782301 doi: 10.1111/j.1464-410X.2008.08067.x
Levine LA, Becher E, Bella A, Brant W, Kohler T, Martinez-Salamanca JI, et al. Penile prosthesis surgery: current recommendations from the international consultation on sexual medicine. J Sex Med. 2016;13:489–518.
pubmed: 27045255 doi: 10.1016/j.jsxm.2016.01.017
McKibben MJ, Shakir N, Fuchs JS, Scott JM, Morey AF. Erosion rates of 3.5-cm artificial urinary sphincter cuffs are similar to larger cuffs. BJU Int. 2019;123:335–41.
pubmed: 30007096 doi: 10.1111/bju.14483
Simhan J, Morey Allen F, Singla N, Tausch Timothy J, Scott JF, Lemack Gary E, et al. 3.5 cm artificial urinary sphincter cuff erosion occurs predominantly in irradiated patients. J Urol. 2015;193:593–7.
pubmed: 25106901 doi: 10.1016/j.juro.2014.07.115
Cordon BH, Singla N, Singla AK. Artificial urinary sphincters for male stress urinary incontinence: current perspectives. Med Devices (Auckl). 2016;9:175–83.
pubmed: 27445509
Kretschmer A, Buchner A, Grabbert M, Stief CG, Pavlicek M, Bauer RM. Risk factors for artificial urinary sphincter failure. World J Urol. 2016;34:595–602.
pubmed: 26253655 doi: 10.1007/s00345-015-1662-9
Clemens JQ, Schuster TG, Konnak JW, McGuire EJ, Faerber GJ. Revision rate after artificial urinary sphincter implantation for incontinence after radical prostatectomy: actuarial analysis. J Urol. 2001;166:1372–5.
pubmed: 11547077 doi: 10.1016/S0022-5347(05)65772-2
Comiter CV. Surgery Insight: surgical management of postprostatectomy incontinence—the artificial urinary sphincter and male sling. Nat Clin Pract Urol. 2007;4:615–24.
pubmed: 17982438 doi: 10.1038/ncpuro0935
Kim SP, Sarmast Z, Daignault S, Faerber GJ, McGuire EJ, Latini JM. Long-term durability and functional outcomes among patients with artificial urinary sphincters: a 10-year retrospective review from the University of Michigan. J Urol. 2008;179:1912–6.
pubmed: 18353376 doi: 10.1016/j.juro.2008.01.048
Giammò A, Ammirati E, Tullio A, Bodo G, Manassero A, Gontero P, et al. Implant of ATOMS® system for the treatment of postoperative male stress urinary incontinence: results of a single centre. Int Braz J Urol. 2019;45:127–36.
pubmed: 30521175 pmcid: 6442148 doi: 10.1590/s1677-5538.ibju.2018.0171
Bauer W, Karik M, Schramek P. The self‐anchoring transobturator male sling to treat stress urinary incontinence in men: a new sling, a surgical approach and anatomical findings in a cadaveric study. BJU Int. 2005;95:1364–6.
pubmed: 15892832 doi: 10.1111/j.1464-410X.2005.05530.x
Hübner WA, Schlarp OM. Treatment of incontinence after prostatectomy using a new minimally invasive device: adjustable continence therapy. BJU Int. 2005;96:587–94.
pubmed: 16104915 doi: 10.1111/j.1464-410X.2005.05689.x
Lebret T, Cour F, Benchetrit J, Grise P, Bernstein J, Delaporte V, et al. Treatment of postprostatectomy stress urinary incontinence using a minimally invasive adjustable continence balloon device, ProACT: results of a preliminary, multicenter, pilot study. Urology. 2008;71:256–60.
pubmed: 18308096 doi: 10.1016/j.urology.2007.08.062
Trigo-Rocha F, Gomes CM, Pompeo ACL, Lucon AM, Arap S. Prospective study evaluating efficacy and safety of adjustable continence therapy (ProACT) for post radical prostatectomy urinary incontinence. Urology. 2006;67:965–9.
pubmed: 16698356 doi: 10.1016/j.urology.2005.11.011
Staerman F, G-Llorens C, Leon P, Leclerc Y. ZSI 375 artificial urinary sphincter for male urinary incontinence: a preliminary study. BJU Int. 2013;111:E202–6.
pubmed: 22937774 doi: 10.1111/j.1464-410X.2012.11468.x
Basiri A, Dadpour M. A case report of the preferred indication for the Zephyr (ZSI 375) artificial urinary sphincter. Urol Case Rep. 2022;43:102058.
pubmed: 35321262 pmcid: 8935498 doi: 10.1016/j.eucr.2022.102058
Llorens C, Pottek T. Urinary artificial sphincter ZSI 375 for treatment of stress urinary incontinence in men: 5 and 7 years follow-up report. Urologia. 2017;84:263–6.
pubmed: 28525665 doi: 10.5301/uj.5000243

Auteurs

Lauren Chew (L)

Department of Urology, Fox Chase Cancer Center, Philadelphia, PA, USA.

Chrystal Chang (C)

Department of Urology, Fox Chase Cancer Center, Philadelphia, PA, USA.

Jay Simhan (J)

Department of Urology, Fox Chase Cancer Center, Philadelphia, PA, USA. jsimhan@gmail.com.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH