Impact of childhood leukemia on siblings: their long-term perception of family functioning and its relationship with their psychosocial characteristics using structural equation modeling.
Childhood leukemia
Family functioning
Long-term follow-up
Siblings
Survivors
Journal
Journal of cancer survivorship : research and practice
ISSN: 1932-2267
Titre abrégé: J Cancer Surviv
Pays: United States
ID NLM: 101307557
Informations de publication
Date de publication:
10 May 2023
10 May 2023
Historique:
received:
06
02
2023
accepted:
14
04
2023
medline:
10
5
2023
pubmed:
10
5
2023
entrez:
10
5
2023
Statut:
aheadofprint
Résumé
In the context of pediatric cancer, siblings' adaptation and needs have been previously investigated; however, research on the long-term consequences on siblings, especially on their family environment, is scarce. We aimed to (1) assess the family functioning (FF) perceived by siblings of childhood leukemia survivors long after diagnosis and (2) explore characteristics likely associated and investigate associations with psycho-behavioral and social factors. Childhood leukemia survivors' siblings older than 11 years were recruited through the LEA cohort, a French long-term follow-up program, and completed the family assessment device (FAD). Logistic regression analysis was used to determine factors likely associated with unhealthy functioning in families as perceived by siblings. Structural equation modeling (SEM) was used to examine relationships that predict siblings' perception of FF. We included 605 siblings (mean follow-up time from diagnosis 14.1 ± 6.8 years), of whom 175 (28.9%) perceived unhealthy functioning. SEM showed that older siblings were more likely to perceive problematic functioning (β = 0.095, p = 0.014). Sex and leukemia burden had indirect effects on FF through mediators. Family financial situation at diagnosis was not associated with the risk of reporting unhealthy functioning. Our study contributed to identifying siblings at risk of facing family issues and reinforced the need to provide more consideration and suitable resources to avoid late consequences. Often considered as the "forgotten children", future research should focus on developing targeted interventions to facilitate family communication and improve siblings' social support. Overall, results regarding FF perceived by siblings are reassuring and provide new enlightening elements that allow for better support to all families.
Identifiants
pubmed: 37162684
doi: 10.1007/s11764-023-01385-2
pii: 10.1007/s11764-023-01385-2
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Assistance Publique - Hôpitaux de Marseille
ID : Valo_APHM_2021
Organisme : Assistance Publique - Hôpitaux de Marseille
ID : AORC_APHM_2014
Organisme : Institut National Du Cancer
ID : INCA2016-117
Organisme : French National Clinical Research Program
ID : PHRC-I_ 2016
Informations de copyright
© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
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