[Vasoprotective effect of effective lipid-lowering therapy in patients with

To study the vasoprotective effects of atorvastatin depending on the achievement of the target level of low-density lipoprotein cholesterol (LDL-C) in patients with Included were 112 When examining the carotid arteries in the HET group, the intima-media thickness (IMT) decreased by 10.7-13.1%, the b index - by 14.9-26.3% after 24-48 weeks. In the RET group, the IMT regression was 10.4-13.3%; b index - 23.9% by the 48th week. In the IET group, the b index decreased by the 48th week by 14.3%. According to applanation tonometry in the HET group, the central pressure did not change. In the RET group, systolic pressure in the aorta increased by 10-15.7% after 24-48 weeks, pulse pressure - by 33.9% by the end of observation. With IET, the increase was 8.6-6.8 and 19.8-25.9%, respectively. The odds ratio of developing endpoints in the RET group was 4.7 (95% CI 1.2-26.4; The most pronounced vasoprotective effect and a decrease in cardiovascular risk are associated with the achievement of the target LDL-C throughout the entire treatment period. Цель. Изучить вазопротективные эффекты аторвастатина в зависимости от достижения целевого уровня холестерина липопротеидов низкой плотности (ХС ЛНП) у больных с инфарктом миокарда с подъемом сегмента