Incidental Detection of Dual Spinal Meningiomas on 68 Ga-DOTATATE PET/CT Masquerading as Metastatic Disease in a Patient With Pulmonary Carcinoid Tumor.


Journal

Clinical nuclear medicine
ISSN: 1536-0229
Titre abrégé: Clin Nucl Med
Pays: United States
ID NLM: 7611109

Informations de publication

Date de publication:
01 Jul 2023
Historique:
medline: 7 6 2023
pubmed: 11 5 2023
entrez: 11 5 2023
Statut: ppublish

Résumé

Simultaneous occurrence of multiple meningiomas of the spine appearing at different neuroaxial levels is extremely rare event. We present the scintigraphic findings of incidentally detected multiple meningiomas of the spine on 68 Ga-DOTATATE PET/CT during the evaluation of a patient with pulmonary carcinoid tumor. These scintigraphic findings could result in a "false-positive" interpretation by exhibiting highly increased uptake similar to that of metastases of neuroendocrine neoplasm. Nuclear medicine physicians should be aware of this potential pitfall in somatostatin receptor imaging to prevent misinterpretation.

Identifiants

pubmed: 37167240
doi: 10.1097/RLU.0000000000004681
pii: 00003072-202307000-00030
doi:

Substances chimiques

copper dotatate CU-64 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e334-e337

Informations de copyright

Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflicts of interest and sources of funding: none declared.

Références

Watts J, Box G, Galvin A, et al. Magnetic resonance imaging of meningiomas: a pictorial review. Insights Imaging . 2014;5:113–122.
Subramaniam RM, Bradshaw ML, Lewis K, et al. ACR practice parameter for the performance of gallium-68 DOTATATE PET/CT for neuroendocrine tumors. Clin Nucl Med . 2018;43:899–908.
Prasad V, Steffen IG, Pavel M, et al. Somatostatin receptor PET/CT in restaging of typical and atypical lung carcinoids. EJNMMI Res . 2015;5:53.
Palmisciano P, Watanabe G, Conching A, et al. The role of [ 68 Ga]Ga-DOTA-SSTR PET radiotracers in brain tumors: a systematic review of the literature and ongoing clinical trials. Cancer . 2022;14:2925.
Afshar-Oromieh A, Giesel FL, Linhart HG, et al. Detection of cranial meningiomas: comparison of 68 Ga-DOTATOC PET/CT and contrast-enhanced MRI. Eur J Nucl Med Mol Imaging . 2012;39:1409–1415.
Koech F, Orege J, Ndiangui F, et al. Multiple intracranial meningiomas: a review of the literature and a case report. Case Rep Surg . 2013;2013:131962.
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Solero CL, Fornari M, Giombini S, et al. Spinal meningiomas: review of 174 operated cases. Neurosurgery . 1989;25:153–160.
Jain SK, Sundar IV, Sharma V, et al. Multiple spinal and cranial meningiomas: a case report and review of literature. Asian J Neurosurg . 2015;10:132–134.
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Patronas NJ, Brown F, Duda EE. Multiple meningiomas in the spinal canal. Surg Neurol . 1980;13:78–80.
Chaparro MJ, Young RF, Smith M, et al. Multiple spinal meningiomas: a case of 47 distinct lesions in the absence of neurofibromatosis or identified chromosomal abnormality. Neurosurgery . 1993;32:298–302.
Silva JA, Holanda MM, Araújo AF, et al. Multiple meningiomas within the spinal canal: case report with 23 tumors. Arq Neuropsiquiatr . 2005;63:166–170.

Auteurs

Nir Hod (N)

From the Institute of Nuclear Medicine and Molecular Imaging, Soroka University Medical Center (Affiliated to Ben Gurion University of the Negev, Faculty of Health Sciences), Beer-Sheva, Israel.

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